Search Results - "Healy, Jasmine"

Contribution of polymorphisms in IKZF1 gene to childhood acute leukemia: a meta-analysis of 33 case-control studies by Dai, Yue-e, Tang, Linjun, Healy, Jasmine, Sinnett, Daniel

“…Two common polymorphisms in the IKZF1 gene (rs4132601 and rs11978267 variants) have been reported to be associated with childhood acute leukemia (AL) risk,…”
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Replication analysis confirms the association of ARID5B with childhood B-cell acute lymphoblastic leukemia by HEALY, Jasmine, RICHER, Chantal, BOURGEY, Mathieu, KRITIKOU, Ekaterini A, SINNETT, Daniel

“…Although childhood acute lymphoblastic leukemia is the most common pediatric cancer, its etiology remains poorly understood. In an attempt to replicate the…”
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CLIC5: a novel ETV6 target gene in childhood acute lymphoblastic leukemia by Neveu, Benjamin, Spinella, Jean-François, Richer, Chantal, Lagacé, Karine, Cassart, Pauline, Lajoie, Mathieu, Jananji, Silvana, Drouin, Simon, Healy, Jasmine, Hickson, Gilles R X, Sinnett, Daniel

“…The most common rearrangement in childhood precursor B-cell acute lymphoblastic leukemia is the t(12;21)(p13;q22) translocation resulting in the ETV6-AML1…”
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Whole-exome sequencing reveals a rapid change in the frequency of rare functional variants in a founding population of humans by Casals, Ferran, Hodgkinson, Alan, Hussin, Julie, Idaghdour, Youssef, Bruat, Vanessa, de Maillard, Thibault, Grenier, Jean-Christophe, Grenier, Jean-Cristophe, Gbeha, Elias, Hamdan, Fadi F, Girard, Simon, Spinella, Jean-François, Larivière, Mathieu, Saillour, Virginie, Healy, Jasmine, Fernández, Isabel, Sinnett, Daniel, Michaud, Jacques L, Rouleau, Guy A, Haddad, Elie, Le Deist, Françoise, Awadalla, Philip

“…Whole-exome or gene targeted resequencing in hundreds to thousands of individuals has shown that the majority of genetic variants are at low frequency in human…”
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Association between CEBPE Variant and Childhood Acute Leukemia Risk: Evidence from a Meta-Analysis of 22 Studies by Sun, Jian, Zheng, Jinyu, Tang, Linjun, Healy, Jasmine, Sinnett, Daniel, Dai, Yue-e

“…The CCAAT/enhancer binding proteins (CEBPs) have been involved in the etiology of acute leukemia (AL) and investigated in numerous genetic association studies,…”
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Mutational dynamics of early and late relapsed childhood ALL: rapid clonal expansion and long-term dormancy by Spinella, Jean-François, Richer, Chantal, Cassart, Pauline, Ouimet, Manon, Healy, Jasmine, Sinnett, Daniel

“…Childhood acute lymphoblastic leukemia (cALL) is the most frequent pediatric cancer. Refractory/relapsed cALL presents a survival rate of ∼45% and is still one…”
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Impact of promoter polymorphisms in key regulators of the intrinsic apoptosis pathway on the outcome of childhood acute lymphoblastic leukemia by Sanchez, Rocio, St-Cyr, Janick, Lalonde, Marie-Eve, Healy, Jasmine, Richer, Chantal, Gagné, Vincent, Laverdière, Caroline, Silverman, Lewis B, Sallan, Stephen E, Neuberg, Donna, Kutok, Jeffery L, Kritikou, Ekaterini A, Krajinovic, Maja, Sinnett, Daniel

“…The introduction of multiagent treatment protocols has led to a remarkable increase in survival rates for children diagnosed with acute lymphoblastic leukemia,…”
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Patient mutations alter ATRX targeting to PML nuclear bodies by BERUBE, Nathalie G, HEALY, Jasmine, MEDINA, Chantal F, SHAOBO WU, HODGSON, Todd, JAGLA, Magdalena, PICKETTS, David J

“…ATRX is a SWI/SNF-like chromatin remodeling protein mutated in several X-linked mental retardation syndromes. Gene inactivation studies in mice demonstrate…”
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No evidence for association between TGFB1 promoter SNPs and the risk of childhood pre-B acute lymphoblastic leukemia among French Canadians by Healy, Jasmine, Roy-Gagnon, Marie-Helene, Sinnett, Daniel

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Connections Between ETV6-Modulated Genes: Identification of Shared Features by Boily, Gino, Beaulieu, Patrick, Healy, Jasmine, Sinnett, Daniel

“…Gino Boily1, Patrick Beaulieu1, Jasmine Healy1 and Daniel Sinnett1,2 1Division of Hematology-Oncology, Charles-Bruneau Cancer Center, Research Center, CHU…”
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SNooPer: a machine learning-based method for somatic variant identification from low-pass next-generation sequencing by Spinella, Jean-François, Mehanna, Pamela, Vidal, Ramon, Saillour, Virginie, Cassart, Pauline, Richer, Chantal, Ouimet, Manon, Healy, Jasmine, Sinnett, Daniel

“…Next-generation sequencing (NGS) allows unbiased, in-depth interrogation of cancer genomes. Many somatic variant callers have been developed yet accurate…”
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Recurrent somatic BRAF insertion (p.V504_R506dup): a tumor marker and a potential therapeutic target in pilocytic astrocytoma by Khater, Fida, Langlois, Sylvie, Cassart, Pauline, Roy, Anne-Marie, Lajoie, Mathieu, Healy, Jasmine, Richer, Chantal, St-Onge, Pascal, Piché, Nelson, Perreault, Sebastien, Cellot, Sonia, Marzouki, Monia, Jabado, Nada, Sinnett, Daniel

“…Pilocytic astrocytoma (PA) is emerging as a tumor entity with dysregulated RAS/RAF/MEK/ERK signaling. In this study, we report the identification of a novel…”
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Genomic characterization of pediatric T-cell acute lymphoblastic leukemia reveals novel recurrent driver mutations by Spinella, Jean-François, Cassart, Pauline, Richer, Chantal, Saillour, Virginie, Ouimet, Manon, Langlois, Sylvie, St-Onge, Pascal, Sontag, Thomas, Healy, Jasmine, Minden, Mark D, Sinnett, Daniel

“…T-cell acute lymphoblastic leukemia (T-ALL) is an aggressive hematologic malignancy with variable prognosis. It represents 15% of diagnosed pediatric ALL cases…”
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Inherited genetic susceptibility to acute lymphoblastic leukemia in Down syndrome by Brown, Austin L., de Smith, Adam J., Gant, Vincent U., Yang, Wenjian, Scheurer, Michael E., Walsh, Kyle M., Chernus, Jonathan M., Kallsen, Noah A., Peyton, Shanna A., Davies, Gareth E., Ehli, Erik A., Winick, Naomi, Heerema, Nyla A., Carroll, Andrew J., Borowitz, Michael J., Wood, Brent L., Carroll, William L., Raetz, Elizabeth A., Feingold, Eleanor, Devidas, Meenakshi, Barcellos, Lisa F., Hansen, Helen M., Morimoto, Libby, Kang, Alice Y., Smirnov, Ivan, Healy, Jasmine, Laverdière, Caroline, Sinnett, Daniel, Taub, Jeffrey W., Birch, Jillian M., Thompson, Pamela, Spector, Logan G., Pombo-de-Oliveira, Maria S., DeWan, Andrew T., Mullighan, Charles G., Hunger, Stephen P., Pui, Ching-Hon, Loh, Mignon L., Zwick, Michael E., Metayer, Catherine, Ma, Xiaomei, Mueller, Beth A., Sherman, Stephanie L., Wiemels, Joseph L., Relling, Mary V., Yang, Jun J., Lupo, Philip J., Rabin, Karen R.

“…Children with Down syndrome (DS) have a 20-fold increased risk of acute lymphoblastic leukemia (ALL) and distinct somatic features, including CRLF2…”
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Variation in CDKN2A at 9p21.3 influences childhood acute lymphoblastic leukemia risk by Gast, Andreas, Kinsey, Sally E, Roman, Eve, Schrappe, Martin, Koeffler, H Phillip, Hosking, Fay J, Stanulla, Martin, Sinnett, Daniel, Harrison, Christine J, Vijayakrishnan, Jayaram, Dobbins, Sara E, Houlston, Richard S, Zimmermann, Martin, Erdelyi, Daniel J, Bartram, Claus R, Richards, Sue, Neira, Anna Gonzalez, Ogawa, Seishi, Healy, Jasmine, Hemminki, Kari, Papaemmanuil, Elli, Kawamata, Norihiko, Semsei, Ágnes F, Irving, Julie A E, Sherborne, Amy L, Kumar, Rajiv, Ma, Yussanne, Moorman, Anthony V, Greaves, Mel, Lightfoot, Tracey, Koehler, Rolf, Prasad, Rashmi B, Taylor, Malcolm, Szalai, Csaba, Sheridan, Eamonn, Allan, James M, Tomlinson, Ian P, Krajinovic, Maja

“…Using data from a genome-wide association study of 907 individuals with childhood acute lymphoblastic leukemia (cases) and 2,398 controls and with validation…”
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A fork in the road: A mixed methods study exploring why older adults with acute myeloid leukemia choose different treatment paths by LeBlanc, Thomas William, Walter, Roland B., Hernandez, Loriana, Morgan, Lucy, Bell, Timothy, Panter, Charlotte, Peloquin, Francois, Healy, Jasmine, Gater, Adam, Welch, Verna, Amer, Karim, O'Hara, Louise, Hohman, Ryan, Brown, Andrew, Russell, Nigel, Merino, Diana M., Horikoshi, Neil, Maze, Dawn

“…Abstract only 7520 Background: Current treatment options for acute myeloid leukemia (AML) are diverse, including intensive chemotherapy (IC), low intensity…”
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A mixed methods study exploring the role of perceived side effects on treatment decision-making in older adults with acute myeloid leukemia (AML) by Maze, Dawn, Walter, Roland B., Merino, Diana M., Bell, Timothy J., O'Hara, Louise, Peloquin, Francois, Morgan, Lucy, Hernandez, Loriana, Healy, Jasmine, Panter, Charlotte, Welch, Verna L., Gater, Adam, Amer, Karim, Hohman, Ryan, Stein, Julia, Brown, Andrew, Russell, Nigel H., LeBlanc, Thomas William

“…Abstract only 7016 Background: AML patients may be treated with intensive chemotherapy (IC), or non-intensive chemotherapy (NIC) or they may receive best…”
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Whole-exome sequencing of a rare case of familial childhood acute lymphoblastic leukemia reveals putative predisposing mutations in Fanconi anemia genes by Spinella, Jean-François, Healy, Jasmine, Saillour, Virginie, Richer, Chantal, Cassart, Pauline, Ouimet, Manon, Sinnett, Daniel

“…Acute lymphoblastic leukemia (ALL) is the most common pediatric cancer. While the multi-step model of pediatric leukemogenesis suggests interplay between…”
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Heritable variation at the chromosome 21 gene ERG is associated with acute lymphoblastic leukemia risk in children with and without Down syndrome by de Smith, Adam J., Walsh, Kyle M., Morimoto, Libby M., Francis, Stephen S., Hansen, Helen M., Jeon, Soyoung, Gonseth, Semira, Chen, Minhui, Sun, Hanxiao, Luna-Fineman, Sandra, Antillón, Federico, Girón, Verónica, Kang, Alice Y., Smirnov, Ivan, Shao, Xiaorong, Whitehead, Todd P., Barcellos, Lisa F., Jolly, Kent W., Healy, Jasmine, Laverdière, Caroline, Sinnett, Daniel, Taub, Jeffrey W., Birch, Jillian M., Thompson, Pamela D., Pombo-de-Oliveira, Maria S., Spector, Logan G., DeWan, Andrew T., Mueller, Beth A., Chiang, Charleston, Metayer, Catherine, Ma, Xiaomei, Wiemels, Joseph L.

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Integration of High-Resolution Methylome and Transcriptome Analyses to Dissect Epigenomic Changes in Childhood Acute Lymphoblastic Leukemia by BUSCHE, Stephan, BING GE, PASTINEN, Tomi, VIDAL, Ramon, SPINELLA, Jean-François, SAILLOUR, Virginie, RICHER, Chantal, HEALY, Jasmine, CHEN, Shu-Huang, DROIT, Arnaud, SINNETT, Daniel

“…B-cell precursor acute lymphoblastic leukemia (pre-B ALL) is the most common pediatric cancer. Although the genetic determinants underlying disease onset…”
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