Search Results - "Healy, Connor P."
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High-throughput enrichment and isolation of megakaryocyte progenitor cells from the mouse bone marrow
Published in Scientific reports (15-04-2021)“…Megakaryocytes are a rare population of cells that develop in the bone marrow and function to produce platelets that circulate throughout the body and form…”
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Lower frequencies of circulating suppressive regulatory T cells and higher frequencies of CD4+ naïve T cells at baseline are associated with severe immune-related adverse events in immune checkpoint inhibitor-treated melanoma
Published in Journal for immunotherapy of cancer (17-01-2024)“…BackgroundImmune-related adverse events (irAEs) are major barriers of clinical management and further development of immune checkpoint inhibitors (ICIs) for…”
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Biological Cells as Therapeutic Delivery Vehicles
Published in Trends in pharmacological sciences (Regular ed.) (01-02-2021)“…One of the significant challenges remaining in the field of drug delivery is insufficient targeting of diseased tissues or cells. While efforts to perform…”
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Abstract 2138: Immune features of irAEs and aPD1 response in urothelial cancer patients of the RADIOHEAD study, as detected in blood by mass cytometry immune profiling
Published in Cancer research (Chicago, Ill.) (04-04-2023)“…Checkpoint immunotherapies (CPI) have resulted in long lasting clinical responses; however, CPI treatment comes with the risk of immune-related adverse events…”
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