Search Results - "Headon, Denis"

Hierarchical patterning modes orchestrate hair follicle morphogenesis by Glover, James D, Wells, Kirsty L, Matthäus, Franziska, Painter, Kevin J, Ho, William, Riddell, Jon, Johansson, Jeanette A, Ford, Matthew J, Jahoda, Colin A B, Klika, Vaclav, Mort, Richard L, Headon, Denis J

“…Two theories address the origin of repeating patterns, such as hair follicles, limb digits, and intestinal villi, during development. The Turing…”
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Morphological mutations: lessons from the cockscomb by Headon, Denis

“…  Mutation of gene regulatory sequences could, in principle, influence gene activity in only one or a few tissues, enabling new morphologies with beneficial…”
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Feather arrays are patterned by interacting signalling and cell density waves by Ho, William K W, Freem, Lucy, Zhao, Debiao, Painter, Kevin J, Woolley, Thomas E, Gaffney, Eamonn A, McGrew, Michael J, Tzika, Athanasia, Milinkovitch, Michel C, Schneider, Pascal, Drusko, Armin, Matthäus, Franziska, Glover, James D, Wells, Kirsty L, Johansson, Jeanette A, Davey, Megan G, Sang, Helen M, Clinton, Michael, Headon, Denis J

“…Feathers are arranged in a precise pattern in avian skin. They first arise during development in a row along the dorsal midline, with rows of new feather buds…”
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Systems for intricate patterning of the vertebrate anatomy by Painter, Kevin J, Ptashnyk, Mariya, Headon, Denis J

“…Periodic patterns form intricate arrays in the vertebrate anatomy, notably the hair and feather follicles of the skin, but also internally the villi of the gut…”
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A chemotaxis model of feather primordia pattern formation during avian development by Painter, Kevin J., Ho, William, Headon, Denis J.

“…•We develop an integrated cell/molecular based model for feather primordia formation during early chicken development.•Linear stability analysis is employed to…”
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Cryptic patterning of avian skin confers a developmental facility for loss of neck feathering by Mou, Chunyan, Pitel, Frederique, Gourichon, David, Vignoles, Florence, Tzika, Athanasia, Tato, Patricia, Yu, Le, Burt, Dave W, Bed'hom, Bertrand, Tixier-Boichard, Michele, Painter, Kevin J, Headon, Denis J

“…Vertebrate skin is characterized by its patterned array of appendages, whether feathers, hairs, or scales. In avian skin the distribution of feathers occurs on…”
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Genome-wide SNP scan of pooled DNA reveals nonsense mutation in FGF20 in the scaleless line of featherless chickens by Wells, Kirsty L, Hadad, Yair, Ben-Avraham, Danny, Hillel, Jossi, Cahaner, Avigdor, Headon, Denis J

“…Scaleless (sc/sc) chickens carry a single recessive mutation that causes a lack of almost all body feathers, as well as foot scales and spurs, due to a failure…”
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Rapid mechanosensitive migration and dispersal of newly divided mesenchymal cells aid their recruitment into dermal condensates by Riddell, Jon, Noureen, Shahzeb Raja, Sedda, Luigi, Glover, James D, Ho, William K. W, Bain, Connor A, Berbeglia, Arianna, Brown, Helen, Anderson, Calum, Chen, Yuhang, Crichton, Michael L, Yates, Christian A, Mort, Richard L, Headon, Denis J

“…Embryonic mesenchymal cells are dispersed within an extracellular matrix but can coalesce to form condensates with key developmental roles. Cells within…”
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Mutations in ACTRT1 and its enhancer RNA elements lead to aberrant activation of Hedgehog signaling in inherited and sporadic basal cell carcinomas by Bal, Elodie, Park, Hyun-Sook, Belaid-Choucair, Zakia, Kayserili, Hülya, Naville, Magali, Madrange, Marine, Chiticariu, Elena, Hadj-Rabia, Smail, Cagnard, Nicolas, Kuonen, Francois, Bachmann, Daniel, Huber, Marcel, Le Gall, Cindy, Côté, Francine, Hanein, Sylvain, Rosti, Rasim Özgür, Aslanger, Ayca Dilruba, Waisfisz, Quinten, Bodemer, Christine, Hermine, Olivier, Morice-Picard, Fanny, Labeille, Bruno, Caux, Frédéric, Mazereeuw-Hautier, Juliette, Philip, Nicole, Levy, Nicolas, Taieb, Alain, Avril, Marie-Françoise, Headon, Denis J, Gyapay, Gabor, Magnaldo, Thierry, Fraitag, Sylvie, Crollius, Hugues Roest, Vabres, Pierre, Hohl, Daniel, Munnich, Arnold, Smahi, Asma

“…Inactivating mutations in ACTRT1 or surrounding noncoding sequences transcribed into functional enhancer RNAs cause aberrant activation of Hedgehog signaling…”
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Hair Follicle Bulge Stem Cells Appear Dispensable for the Acute Phase of Wound Re‐epithelialization by Garcin, Clare L., Ansell, David M., Headon, Denis J., Paus, Ralf, Hardman, Matthew J.

“…The cutaneous healing response has evolved to occur rapidly, in order to minimize infection and to re‐establish epithelial homeostasis. Rapid healing is…”
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The developmental basis of fingerprint pattern formation and variation by Glover, James D., Sudderick, Zoe R., Shih, Barbara Bo-Ju, Batho-Samblas, Cameron, Charlton, Laura, Krause, Andrew L., Anderson, Calum, Riddell, Jon, Balic, Adam, Li, Jinxi, Klika, Václav, Woolley, Thomas E., Gaffney, Eamonn A., Corsinotti, Andrea, Anderson, Richard A., Johnston, Luke J., Brown, Sara J., Wang, Sijia, Chen, Yuhang, Crichton, Michael L., Headon, Denis J.

“…Fingerprints are complex and individually unique patterns in the skin. Established prenatally, the molecular and cellular mechanisms that guide fingerprint…”
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Isolating Patterns in Open Reaction–Diffusion Systems by Krause, Andrew L., Klika, Václav, Maini, Philip K., Headon, Denis, Gaffney, Eamonn A.

“…Realistic examples of reaction–diffusion phenomena governing spatial and spatiotemporal pattern formation are rarely isolated systems, either chemically or…”
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GWASs Identify Genetic Loci Associated with Human Scalp Hair Whorl Direction by Luo, Junyu, Huang, He, Qiao, Hui, Tan, Jingze, Chen, Wenyan, Zhang, Manfei, Ruiz-Linares, Andrés, Wang, Jiucun, Yang, Yajun, Jin, Li, Headon, Denis J., Wang, Sijia

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An Extended Epidermal Response Heals Cutaneous Wounds in the Absence of a Hair Follicle Stem Cell Contribution by Langton, Abigail K., Herrick, Sarah E., Headon, Denis J.

“…Hair follicles have been observed to provide a major cellular contribution to epidermal healing, with emigration of stem-derived cells from the follicles…”
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The Interfollicular Epidermis of Adult Mouse Tail Comprises Two Distinct Cell Lineages that Are Differentially Regulated by Wnt, Edaradd, and Lrig1 by Gomez, Céline, Chua, Wesley, Miremadi, Ahmad, Quist, Sven, Headon, Denis J., Watt, Fiona M.

“…Current models of how mouse tail interfollicular epidermis (IFE) is maintained overlook the coexistence of two distinct terminal differentiation programs:…”
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Enhanced Edar signalling has pleiotropic effects on craniofacial and cutaneous glands by Chang, Shie Hong, Jobling, Stephanie, Brennan, Keith, Headon, Denis J

“…The skin carries a number of appendages, including hair follicles and a range of glands, which develop under the influence of EDAR signalling. A gain of…”
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Limb development genes underlie variation in human fingerprint patterns by Li, Jinxi, Glover, James D., Zhang, Haiguo, Peng, Meifang, Tan, Jingze, Mallick, Chandana Basu, Hou, Dan, Yang, Yajun, Wu, Sijie, Liu, Yu, Peng, Qianqian, Zheng, Shijie C., Crosse, Edie I., Medvinsky, Alexander, Anderson, Richard A., Brown, Helen, Yuan, Ziyu, Zhou, Shen, Xu, Yanqing, Kemp, John P., Ho, Yvonne Y.W., Loesch, Danuta Z., Wang, Lizhong, Li, Yingxiang, Tang, Senwei, Wu, Xiaoli, Walters, Robin G., Lin, Kuang, Meng, Ruogu, Lv, Jun, Chernus, Jonathan M., Neiswanger, Katherine, Feingold, Eleanor, Evans, David M., Medland, Sarah E., Martin, Nicholas G., Weinberg, Seth M., Marazita, Mary L., Chen, Gang, Chen, Zhengming, Zhou, Yong, Cheeseman, Michael, Wang, Lan, Jin, Li, Headon, Denis J., Wang, Sijia

“…Fingerprints are of long-standing practical and cultural interest, but little is known about the mechanisms that underlie their variation. Using genome-wide…”
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Methods for the Administration of EDAR Pathway Modulators in Mice by Schuepbach-Mallepell, Sonia, Kowalczyk-Quintas, Christine, Dick, Angela, Eslami, Mahya, Vigolo, Michele, Headon, Denis J, Cheeseman, Michael, Schneider, Holm, Schneider, Pascal

“…Genetic deficiency of ectodysplasin A (EDA) causes X-linked hypohidrotic ectodermal dysplasia, a congenital condition characterized by the absence or abnormal…”
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Elevated EDAR signalling promotes mammary gland tumourigenesis with squamous metaplasia by Williams, Rebecca, Jobling, Stephanie, Sims, Andrew H., Mou, Chunyan, Wilkinson, Lorna, Collu, Giovanna M., Streuli, Charles H., Gilmore, Andrew P., Headon, Denis J., Brennan, Keith

“…Ectodysplasin A receptor (EDAR) is a death receptor in the Tumour Necrosis Factor Receptor (TNFR) superfamily with roles in the development of hair follicles,…”
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The Enrichment of Specific Hair Follicle-Associated Cell Populations in Plucked Hairs Offers an Opportunity to Study Gene Expression Underlying Hair Traits by Naboulsi, Rakan, Cieślak, Jakub, Headon, Denis, Jouni, Ahmad, Negro, Juan J, Andersson, Göran, Lindgren, Gabriella

“…Gene expression differences can assist in characterizing important underlying genetic mechanisms between different phenotypic traits. However, when…”
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