Search Results - "Headley, Kathryn M."
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Chemical screen for epigenetic barriers to single allele activation of Oct4
Published in Stem cell research (01-07-2019)“…Here we utilized the chromatin in vivo assay (CiA) mouse platform to directly examine the epigenetic barriers impeding the activation of the CiA:Oct4 allele in…”
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Marker-free quantification of repair pathway utilization at Cas9-induced double-strand breaks
Published in Nucleic acids research (21-05-2021)“…Abstract Genome integrity and genome engineering require efficient repair of DNA double-strand breaks (DSBs) by non-homologous end joining (NHEJ), homologous…”
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Abstract 3234: Covalent capture of protein binding partners using an azide-tagged, photo-reactive stapled alpha helical p53 peptide
Published in Cancer research (Chicago, Ill.) (01-10-2014)“…Abstract Mutations in the DNA binding region of tumor suppressor p53 render it transcriptionally inactive (dominant negative) but can also manifest in…”
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Abstract 2223: Identification of novel protein modulators of p53 family function using photochemical crosslinking of stapled peptides
Published in Cancer research (Chicago, Ill.) (15-04-2013)“…Abstract Considered to be the “guardian of the genome,” the tumor suppressor p53 works to counteract genetic mutation through cell cycle arrest, DNA repair or…”
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