Search Results - "Head, Steven R"
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long noncoding RNA THRIL regulates TNFα expression through its interaction with hnRNPL
Published in Proceedings of the National Academy of Sciences - PNAS (21-01-2014)“…Thousands of large intergenic noncoding RNAs (lincRNAs) have been identified in the mammalian genome, many of which have important roles in regulating a…”
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2
An Evolutionarily Conserved Long Noncoding RNA TUNA Controls Pluripotency and Neural Lineage Commitment
Published in Molecular cell (20-03-2014)“…Here, we generated a genome-scale shRNA library targeting long intergenic noncoding RNAs (lincRNAs) in the mouse. We performed an unbiased loss-of-function…”
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3
Library construction for next-generation sequencing: overviews and challenges
Published in BioTechniques (01-02-2014)“…High-throughput sequencing, also known as next-generation sequencing (NGS), has revolutionized genomic research. In recent years, NGS technology has steadily…”
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4
Directional RNA deep sequencing sheds new light on the transcriptional response of Anabaena sp. strain PCC 7120 to combined-nitrogen deprivation
Published in BMC genomics (28-06-2011)“…Cyanobacteria are potential sources of renewable chemicals and biofuels and serve as model organisms for bacterial photosynthesis, nitrogen fixation, and…”
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5
Technical Variations in Low-Input RNA-seq Methodologies
Published in Scientific reports (14-01-2014)“…Recent advances in RNA-seq methodologies from limiting amounts of mRNA have facilitated the characterization of rare cell-types in various biological systems…”
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6
Noncoding transcription within the Igh distal VH region at PAIR elements affects the 3D structure of the Igh locus in pro-B cells
Published in Proceedings of the National Academy of Sciences - PNAS (16-10-2012)“…Noncoding sense and antisense germ-line transcription within the Ig heavy chain locus precedes V(D)J recombination and has been proposed to be associated with…”
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7
Transfection of microRNA Mimics Should Be Used with Caution
Published in Frontiers in genetics (02-12-2015)“…Transient transfection of chemically synthesized microRNA (miRNA) mimics is being used extensively to study the functions and mechanisms of endogenous miRNAs…”
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8
Loss of GCNT2/I-branched glycans enhances melanoma growth and survival
Published in Nature communications (22-08-2018)“…Cancer cells often display altered cell-surface glycans compared to their nontransformed counterparts. However, functional contributions of glycans to cancer…”
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Increased sensitivity using real-time dPCR for detection of SARS-CoV-2
Published in BioTechniques (01-01-2021)“…A real-time dPCR system was developed to improve the sensitivity, specificity and quantification accuracy of end point dPCR. We compared three technologies –…”
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10
Differential Sensitivity of Target Genes to Translational Repression by miR-17~92
Published in PLoS genetics (27-02-2017)“…MicroRNAs (miRNAs) are thought to exert their functions by modulating the expression of hundreds of target genes and each to a small degree, but it remains…”
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11
Identification of Key Determinants of Staphylococcus aureus Vaginal Colonization
Published in mBio (24-12-2019)“…is an important pathogen responsible for nosocomial and community-acquired infections in humans, and methicillin-resistant (MRSA) infections have continued to…”
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12
Genome-wide identification of Bcl11b gene targets reveals role in brain-derived neurotrophic factor signaling
Published in PloS one (01-09-2011)“…B-cell leukemia/lymphoma 11B (Bcl11b) is a transcription factor showing predominant expression in the striatum. To date, there are no known gene targets of…”
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13
Quantitative bias in Illumina TruSeq and a novel post amplification barcoding strategy for multiplexed DNA and small RNA deep sequencing
Published in PloS one (28-10-2011)“…Here we demonstrate a method for unbiased multiplexed deep sequencing of RNA and DNA libraries using a novel, efficient and adaptable barcoding strategy called…”
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14
Defining the Pseudomonas aeruginosa SOS Response and Its Role in the Global Response to the Antibiotic Ciprofloxacin
Published in Journal of Bacteriology (01-10-2006)“…Article Usage Stats Services JB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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15
Seasonal dynamics of DNA and RNA viral bioaerosol communities in a daycare center
Published in Microbiome (01-04-2019)“…Viruses play an important role in ecosystems, including the built environment (BE). While numerous studies have characterized bacterial and fungal microbiomes…”
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16
Shared and Compartment‐Specific Processes in Nucleus Pulposus and Annulus Fibrosus During Intervertebral Disc Degeneration
Published in Advanced science (01-05-2024)“…Elucidating how cell populations promote onset and progression of intervertebral disc degeneration (IDD) has the potential to enable more precise therapeutic…”
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17
Kinetic analysis of a complete poxvirus transcriptome reveals an immediate-early class of genes
Published in Proceedings of the National Academy of Sciences - PNAS (12-02-2008)“…Vaccinia virus is the prototypic orthopoxvirus and was the vaccine used to eradicate smallpox, yet the expression profiles of many of its genes remain unknown…”
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18
A genome-wide survey of mutations in the Jurkat cell line
Published in BMC genomics (08-05-2018)“…The Jurkat cell line has an extensive history as a model of T cell signaling. But at the turn of the 21st century, some expression irregularities were…”
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Helicobacter pylori induces β3GnT5 in human gastric cell lines, modulating expression of the SabA ligand sialyl–Lewis x
Published in The Journal of clinical investigation (01-06-2008)“…Chronic Helicobacter pylori infection is recognized as a cause of gastric cancer. H. pylori adhesion to gastric cells is mediated by bacterial adhesins such as…”
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20
Evidence for disruption of sphingolipid metabolism in schizophrenia
Published in Journal of neuroscience research (01-01-2009)“…As the field of glycobiology grows, important roles for glycolipids and glycoproteins in neurological disorders are being increasingly appreciated. However,…”
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