Search Results - "Head, J. F."

Mitochondria organelle transplantation: introduction of normal epithelial mitochondria into human cancer cells inhibits proliferation and increases drug sensitivity by Elliott, R. L., Jiang, X. P., Head, J. F.

“…Mitochondrial dysfunction of cancer cells includes increased aerobic glycolysis, elevated levels of ROS, decreased apoptosis, and resistance to…”
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Expression of transferrin receptor and ferritin H-chain mRNA are associated with clinical and histopathological prognostic indicators in breast cancer by Yang, D C, Wang, F, Elliott, R L, Head, J F

“…It is well known that iron plays an essential role in many biochemical reactions and that rapidly growing cells require more iron for their growth and…”
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Melittin Binding Causes a Large Calcium-Dependent Conformational Change in Calmodulin by Kataoka, Mikio, Head, James F., Seaton, Barbara A., Engelman, Donald M.

“…The interaction between calmodulin and its target protein is a key step in many calcium-regulated cellular functions. Melittin binds tightly to calmodulin in…”
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Mutational and Crystallographic Analyses of Interfacial Residues in Annexin V Suggest Direct Interactions with Phospholipid Membrane Components by Campos, B, Mo, Y. D, Mealy, T. R, Li, C. W, Swairjo, M. A, Balch, C, Head, J. F, Retzinger, G, Dedman, J. R, Seaton, B. A

“…Annexin V belongs to a family of eukaryotic calcium-dependent membrane-binding proteins. The calcium-binding sites at the annexin−membrane interface have been…”
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The crystal structure of the photoprotein aequorin at 2.3 resolution by Head, James F, Inouye, Satoshi, Teranishi, Katsunori, Shimomura, Osamu

“…Aequorin is a calcium-sensitive photoprotein originally obtained from the jellyfish Aequorea aequorea. Because it has a high sensitivity to calcium ions and is…”
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Rat Annexin V Crystal Structure: Ca$^{2+}$-Induced Conformational Changes by Concha, N. O., Head, J. F., Kaetzel, M. A., Dedman, J. R., Seaton, B. A.

“…Annexins are a family of calcium- and phospholipid-binding proteins implicated in mediating membrane-related processes such as secretion, signal transduction,…”
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Inhibition of growth of human breast carcinoma cells by an antisense oligonucleotide targeted to the transferrin receptor gene by Yang, D C, Jiang, X P, Elliott, R L, Head, J F

“…Transferrin receptor expression is controlled by the amount of iron required by the cell to maintain its metabolism and therefore tumor cells in a highly…”
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Inhibitory effect of deferoxamine mesylate and low iron diet on the 13762NF rat mammary adenocarcinoma by Wang, F, Elliott, R L, Head, J F

“…The iron chelator deferoxamine mesylate has been shown to inhibit the growth of a variety of human malignant cell lines and the rat 13762NF mammary…”
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Accelerated partial breast irradiation: Initial experience with the Intrabeam System by Elliott, R.L, DeLand, M, Head, J.F, Elliott, M.C

“…Abstract Failure after breast conserving surgery (BCS) and total breast irradiation usually occurs at the site of the original tumor. This has caused an…”
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Calcium-induced increase in the radius of gyration and maximum dimension of calmodulin measured by small-angle x-ray scattering by Seaton, B. A, Head, J. F, Engelman, D. M, Richards, F. M

“…We have used solution small-angle X-ray scattering to characterize bovine brain calmodulin in the presence and absence of calcium. In the presence of calcium,…”
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The Structure and Function of Xenopus NO38-Core, a Histone Chaperone in the Nucleolus by Namboodiri, V.M.Haridasan, Akey, Ildikó V., Schmidt-Zachmann, Marion S., Head, James F., Akey, Christopher W.

“…Xenopus NO38 is an abundant nucleolar chaperone and a member of the nucleoplasmin (Np) family. Here, we report high-resolution crystal structures of the…”
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Annexin V forms calcium-dependent trimeric units on phospholipid vesicles by Concha, Nestor O., Head, James F., Kaetzel, Marcia A., Dedman, John R., Seaton, Barbara A.

“…The quaternary structure of annexin V, a calcium-dependent phospholipid binding protein, was investigated by chemical cross-linking. Calcium was found to…”
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The Crystal Structure of Nucleoplasmin-Core: Implications for Histone Binding and Nucleosome Assembly by Dutta, Shuchismita, Akey, Ildikó V., Dingwall, Colin, Hartman, Kari L., Laue, Tom, Nolte, Robert T., Head, James F., Akey, Christopher W.

“…The efficient assembly of histone complexes and nucleosomes requires the participation of molecular chaperones. Currently, there is a paucity of data on their…”
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Amino acid sequence of a low molecular weight, high affinity calcium-binding protein from the optic lobe of the squid Loligo pealei by Head, J F

“…The amino acid sequence was determined for squid calcium-binding protein (CaBP), a low molecular weight, high affinity calcium-binding protein from squid optic…”
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Identification of a calsequestrin-like protein from sea urchin eggs by Oberdorf, J A, Lebeche, D, Head, J F, Kaminer, B

“…Following studies on calcium transport by isolated smooth endoplasmic reticulum from unfertilized sea urchin eggs (Oberdorf, J. A., Head, J. F., and Kaminer,…”
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Crystal Structure of Trimeric Carbohydrate Recognition and Neck Domains of Surfactant Protein A by Head, James F., Mealy, Tanya R., McCormack, Francis X., Seaton, Barbara A.

“…Surfactant protein A (SP-A), one of four proteins associated with pulmonary surfactant, binds with high affinity to alveolar phospholipid membranes,…”
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Evaluation of lymphocyte immunity in breast cancer patients by HEAD, J. F, ELLIOTT, R. L, MCCOY, J. L

“…One hundred forty-two breast cancer patients were evaluated for three functional immunologic parameters: the ability of their lymphocytes to proliferate in…”
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The crystal structure of MarR, a regulator of multiple antibiotic resistance, at 2.3 Angstrom resolution by Alekshun, M N, Levy, S B, Mealy, T R, Seaton, BA, Head, J F

“…MarR is a regulator of multiple antibiotic resistance in Escherichia coli. It is the prototypical member of the MarR family of regulatory proteins found in…”
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Thermography. Its relation to pathologic characteristics, vascularity, proliferation rate, and survival of patients with invasive ductal carcinoma of the breast by Head, J F, Elliott, R L

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The Crystal Structure of Drosophila NLP-Core Provides Insight into Pentamer Formation and Histone Binding by Namboodiri, V.M.Haridasan, Dutta, Shuchismita, Akey, Ildikó V, Head, James F, Akey, Christopher W

“…The nucleoplasmin-like protein from Drosophila (dNLP) functions as a chaperone for core histones and may remodel chromatin in embryos. We now report the…”
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