Search Results - "He, Yingzi"

Wnt/β-catenin interacts with the FGF pathway to promote proliferation and regenerative cell proliferation in the zebrafish lateral line neuromast by Tang, Dongmei, He, Yingzi, Li, Wenyan, Li, Huawei

“…Wnt and FGF are highly conserved signaling pathways found in various organs and have been identified as important regulators of auditory organ development. In…”
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Inhibiting DNA methylation alleviates cisplatin-induced hearing loss by decreasing oxidative stress-induced mitochondria-dependent apoptosis via the LRP1–PI3K/AKT pathway by He, Yingzi, Zheng, Zhiwei, Liu, Chang, Li, Wen, Zhao, Liping, Nie, Guohui, Li, Huawei

“…Cisplatin-related ototoxicity is a critical side effect of chemotherapy and can lead to irreversible hearing loss. This study aimed to assess the potential…”
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The miR-182-5p/GPX4 Pathway Contributes to Sevoflurane-Induced Ototoxicity via Ferroptosis by Jin, Lin, Yu, Xiaopei, Zhou, Xuehua, Li, Gang, Li, Wen, He, Yingzi, Li, Huawei, Shen, Xia

“…Our study aimed to investigate the role of ferroptosis in sevoflurane-induced hearing impairment and explore the mechanism of the microRNA-182-5p…”
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A PRMT5 inhibitor protects against noise-induced hearing loss by alleviating ROS accumulation by Liu, Chang, Tang, Dongmei, Zheng, Zhiwei, Lu, Xiaoling, Li, Wen, Zhao, Liping, He, Yingzi, Li, Huawei

“…The aim of this study was to investigate the effect of LLY-283, a selective inhibitor of protein arginine methyltransferase 5 (PRMT5), on a noise-induced…”
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Autophagy: A Novel Horizon for Hair Cell Protection by Liu, Chang, Zheng, Zhiwei, Wang, Pengjun, He, Shuangba, He, Yingzi

“…As a general sensory disorder, hearing loss was a major concern worldwide. Autophagy is a common cellular reaction to stress that degrades cytoplasmic waste…”
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Clinical and genetic analysis of pseudohypoparathyroidism complicated by hypokalemia: a case report and review of the literature by Huang, Shaohan, He, Yingzi, Lin, Xihua, Sun, Shuiya, Zheng, Fenping

“…Pseudohypoparathyroidism (PHP) encompasses a highly heterogenous group of disorders, characterized by parathyroid hormone (PTH) resistance caused by mutations…”
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MiR-182-5p protects inner ear hair cells from cisplatin-induced apoptosis by inhibiting FOXO3a by Li, Yimeng, Li, Ao, Wu, Jingfang, He, Yingzi, Yu, Huiqian, Chai, Renjie, Li, Huawei

“…Cisplatin is widely used for chemotherapy of a variety of malignancies. However, the clinical application of cisplatin is hampered by the resultant…”
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Novel compounds protect auditory hair cells against gentamycin-induced apoptosis by maintaining the expression level of H3K4me2 by Li, Ao, You, Dan, Li, Wenyan, Cui, Yingjie, He, Yingzi, Li, Wen, Chen, Yan, Feng, Xiao, Sun, Shan, Chai, Renjie, Li, Huawei

“…Aminoglycoside-induced hair cell (HC) loss is a major cause of hearing impairment, and the effective prevention of HC loss remains an unmet medical need…”
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Lysine-specific demethylase 1 inhibitors protect cochlear spiral ganglion neurons against cisplatin-induced damage by Li, Ao, He, Yingzi, Sun, Shan, Cai, Chengfu, Li, Huawei

“…Cisplatin is a widely used chemotherapeutic drug, but one of its side effects is ototoxicity. Epigenetic-related drugs, such as lysine-specific demethylase 1…”
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Canagliflozin ameliorates the development of NAFLD by preventing NLRP3-mediated pyroptosis through FGF21-ERK1/2 pathway by Huang, Shaohan, Wu, Beibei, He, Yingzi, Qiu, Ruojun, Yang, Tian, Wang, Shuo, Lei, Yongzhen, Li, Hong, Zheng, Fenping

“…Recent studies have suggested that sodium-glucose co-transporter2 inhibitors go beyond their glycemic advantages to ameliorate the development of NAFLD…”
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Inhibition of H3K4me2 Demethylation Protects Auditory Hair Cells from Neomycin-Induced Apoptosis by He, Yingzi, Yu, Huiqian, Cai, Chengfu, Sun, Shan, Chai, Renjie, Li, Huawei

“…Aminoglycoside-induced hair cell loss is a major cause of hearing impairment in children and deserves more attention in medical research. Epigenetic mechanisms…”
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Inhibition of histone methyltransferase PRMT5 attenuates cisplatin-induced hearing loss through the PI3K/Akt-mediated mitochondrial apoptotic pathway by Zheng, Zhiwei, Nan, Benyu, Liu, Chang, Tang, Dongmei, Li, Wen, Zhao, Liping, Nie, Guohui, He, Yingzi

“…This study aimed to evaluate the therapeutic potential of inhibiting protein arginine methyltransferase 5 (PRMT5) in cisplatin-induced hearing loss. The…”
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Inhibition of H3K27me3 Histone Demethylase Activity Prevents the Proliferative Regeneration of Zebrafish Lateral Line Neuromasts by Bao, Beier, He, Yingzi, Tang, Dongmei, Li, Wenyan, Li, Huawei

“…The H3K27 demethylases are involved in a variety of biological processes, including cell differentiation, proliferation, and cell death by regulating…”
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Insm1a Is Required for Zebrafish Posterior Lateral Line Development by He, Yingzi, Lu, Xiaoling, Qian, Fuping, Liu, Dong, Chai, Renjie, Li, Huawei

“…Insulinoma-associated 1 (Insm1), a zinc-finger transcription factor, is widely expressed in the developing nervous system and plays important roles in cell…”
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Kif15 Is Required in the Development of Auditory System Using Zebrafish as a Model by Zheng, Shimei, Tang, Dongmei, Wang, Xin, Liu, Chang, Zuo, Na, Yan, Renchun, Wu, Cheng, Ma, Jun, Wang, Chuanxi, Xu, Hongfei, He, Yingzi, Liu, Dong, Liu, Shaofeng

“…Kif15, a kinesin family member, is powerful in the formation of bipolar spindles. There is emerging evidence indicating that Kif15 plays vital roles in…”
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Cingulin b Is Required for Zebrafish Lateral Line Development Through Regulation of Mitogen-Activated Protein Kinase and Cellular Senescence Signaling Pathways by Lu, Yitong, Tang, Dongmei, Zheng, Zhiwei, Wang, Xin, Zuo, Na, Yan, Renchun, Wu, Cheng, Ma, Jun, Wang, Chuanxi, Xu, Hongfei, He, Yingzi, Liu, Dong, Liu, Shaofeng

“…Cingulin, a cytoplasmic element of tight junctions (TJs), is involved in maintenance of the integrity of epithelial and endothelial cells. However, the role of…”
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Drag-tracking guidance for entry vehicles with finite time convergence by Yan, Han, He, Yingzi

“…A robust entry guidance law with finite time convergence is designed for drag-tracking in this paper. The bank angle is regarded as the control variable…”
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Study of reentry guidance based on analytical predictor-corrector for aerospace vehicle by Liu, Zhiyong, He, Yingzi

“…For the aerospace vehicle reentry problem, a guidance approach based on analytical predictor-corrector is proposed. In this approach, the guidance is divided…”
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Effect of histone deacetylase inhibitors trichostatin A and valproic acid on hair cell regeneration in zebrafish lateral line neuromasts by He, Yingzi, Cai, Chengfu, Tang, Dongmei, Sun, Shan, Li, Huawei

“…In humans, auditory hair cells are not replaced when injured. Thus, cochlear hair cell loss causes progressive and permanent hearing loss. Conversely,…”
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miR-199a Regulates the Tumor Suppressor Mitogen-Activated Protein Kinase Kinase Kinase 11 in Gastric Cancer by Song, Guang, Zeng, Huazong, Li, Jian, Xiao, Lifeng, He, Yingzi, Tang, Yinhua, Li, Yuru

“…Small noncoding microRNAs (miRNAs) have been shown to play an important role in tumor proliferation and metastasis. However, their function and mechanism in…”
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