Search Results - "He, Xingyao"

Histone H3.3K27M Represses p16 to Accelerate Gliomagenesis in a Murine Model of DIPG by Cordero, Francisco J, Huang, Zhiqing, Grenier, Carole, He, Xingyao, Hu, Guo, McLendon, Roger E, Murphy, Susan K, Hashizume, Rintaro, Becher, Oren J

“…Diffuse intrinsic pontine glioma (DIPG) is a highly aggressive pediatric brainstem tumor genetically distinguished from adult GBM by the high prevalence of the…”
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Resetting the epigenetic balance of Polycomb and COMPASS function at enhancers for cancer therapy by Wang, Lu, Zhao, Zibo, Ozark, Patrick A., Fantini, Damiano, Marshall, Stacy A., Rendleman, Emily J., Cozzolino, Kira A., Louis, Nundia, He, Xingyao, Morgan, Marc A., Takahashi, Yoh-hei, Collings, Clayton K., Smith, Edwin R., Ntziachristos, Panagiotis, Savas, Jeffrey N., Zou, Lihua, Hashizume, Rintaro, Meeks, Joshua J., Shilatifard, Ali

“…The lysine methyltransferase KMT2C (also known as MLL3), a subunit of the COMPASS complex, implements monomethylation of Lys4 on histone H3 (H3K4) at gene…”
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New therapeutic approaches for brainstem tumors: a comparison of delivery routes using nanoliposomal irinotecan in an animal model by Louis, Nundia, Liu, Sharon, He, Xingyao, Drummond, Daryl C., Noble, Charles O., Goldman, Stewart, Mueller, Sabine, Bankiewicz, Krystof, Gupta, Nalin, Hashizume, Rintaro

“…Despite the advances in imaging, surgery and radiotherapy, the majority of patients with brainstem gliomas die within 2 years after initial diagnosis. Factors…”
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Inhibition of polo-like kinase 4 (PLK4): a new therapeutic option for rhabdoid tumors and pediatric medulloblastoma by Sredni, Simone Treiger, Bailey, Anders W, Suri, Amreena, Hashizume, Rintaro, He, Xingyao, Louis, Nundia, Gokirmak, Tufan, Piper, David R, Watterson, Daniel M, Tomita, Tadanori

“…Rhabdoid tumors (RT) are highly aggressive and vastly unresponsive embryonal tumors. They are the most common malignant CNS tumors in infants below 6 months of…”
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Simplified state-space model and validation of irrigation canal systems by Yanggui, Zou, Lihui, Cen, Dewei, Li, Xingyao, He

“…Saint-Venant equations are a set of quasi-linear partial differential equations that represent the canal hydraulics. It is difficult to adapt to control. In…”
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Visible-Light-Induced α‑Arylation of Ketones with (Hetero)aryl Halides by Liang, Chuyun, Wang, Shuzhong, Xue, Yunhao, He, Xingyao, Qin, Jialiang, Zhan, Ruoting, Liu, Bo, Huang, Huicai

“…An enamine-mediated photoredox catalyzed C­(sp2)–C­(sp3) cross-coupling of dual radical precursors for the arylation of ketone is presented in this Letter…”
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Radiosensitization by Histone H3 Demethylase Inhibition in Diffuse Intrinsic Pontine Glioma by Katagi, Hiroaki, Louis, Nundia, Unruh, Dusten, Sasaki, Takahiro, He, Xingyao, Zhang, Ali, Ma, Quanhong, Piunti, Andrea, Shimazu, Yosuke, Lamano, Jonathan B, Carcaboso, Angel M, Tian, Xiao, Seluanov, Andrei, Gorbunova, Vera, Laurie, Kathryn L, Kondo, Akihide, Wadhwani, Nitin R, Lulla, Rishi, Goldman, Stewart, Venneti, Sriram, Becher, Oren J, Zou, Lihua, Shilatifard, Ali, Hashizume, Rintaro

“…Radiotherapy (RT) has long been and remains the only treatment option for diffuse intrinsic pontine glioma (DIPG). However, all patients show evidence of…”
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Intranasal delivery of nanoliposomal SN-38 for treatment of diffuse midline glioma by Sasaki, Takahiro, Watanabe, Jun, He, Xingyao, Katagi, Hiroaki, Suri, Amreena, Ishi, Yukitomo, Abe, Kouki, Natsumeda, Manabu, Frey, William H, Zhang, Peng, Hashizume, Rintaro

“…Diffuse midline gliomas, including diffuse intrinsic pontine gliomas (DIPGs), are among the most malignant and devastating childhood brain cancers. Despite…”
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Therapeutic Targeting of EZH2 and BET BRD4 in Pediatric Rhabdoid Tumors by Ishi, Yukitomo, Zhang, Yongzhan, Zhang, Ali, Sasaki, Takahiro, Piunti, Andrea, Suri, Amreena, Watanabe, Jun, Abe, Kouki, He, Xingyao, Katagi, Hiroaki, Bhalla, Pankaj, Natsumeda, Manabu, Zou, Lihua, Shilatifard, Ali, Hashizume, Rintaro

“…Aberrant activity of the H3K27 modifiers EZH2 and BRD4 is an important oncogenic driver for atypical teratoid/rhabdoid tumor (AT/RT), and each is potentially a…”
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PDTM-36. NEW THERAPEUTIC APPROACH FOR BRAINSTEM GLIOMA: INTRANASAL DELIVERY OF NANOLIPOSOMAL SN-38 by He, Xingyao, Zhang, Peng, Louis, Nundia, Katagi, Hiroaki, Balyasnikova, Irina, Horbinski, Craig, Goldman, Stewart, Hashizume, Rintaro

“…Abstract INTRODUCTION Children with diffuse intrinsic pontine gliomas (DIPGs) die within 2 years after initial diagnosis. The infiltrative nature and anatomic…”
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DIPG-33. NEW THERAPEUTIC APPROACH FOR BRAINSTEM GLIOMA: INTRANASAL DELIVERY OF NANOLIPOSOMAL SN-38 by He, Xingyao, Louis, Nundia, Katagi, Hiroaki, Zhang, Peng, Balyasnikova, Irina, Horbinski, Craig, Goldman, Stewart, Hashizume, Rintaro

“…Abstract INTRODUCTION Children with diffuse intrinsic pontine gliomas (DIPGs) die within 2 years after initial diagnosis. The infiltrative nature and anatomic…”
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SCDT-20. NEW THERAPEUTIC APPROACH FOR BRAINSTEM GLIOMA: INTRANASAL DELIVERY OF NANOLIPOSOMAL SN-38 by He, Xingyao, Louis, Nundia, Zhang, Peng, Balyasnikova, Irina, Horbinski, Craig, Goldman, Stewart, Hashizume, Rintaro

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PDTM-37. NEW THERAPEUTIC APPROACH FOR BRAINSTEM GLIOMA: INTRANASAL DELIVERY OF NANOLIPOSOMAL SN-38 by He, Xingyao, Louis, Nundia, Zhang, Peng, Balyasnikova, Irina, Horbinski, Craig, Goldman, Stewart, Hashizume, Rintaro

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Flexible grid-connection technique of Quasi-Z source photovoltaic power generation system based on direct power control by Yuxun Luo, Zhiyong Li, Xingyao He, Xuexiu Zeng

“…To make the Quasi-Z-source inverter applied in photovoltaic systems better, a flexible grid-connection method based on direct power control is proposed. The…”
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DIPG-36. NOVEL THERAPEUTIC APPROACHES USING NANOLIPOSMAL SN-38 FOR THE TREATMENT OF HUMAN BRAINSTEM GLIOMA by He, Xingyao, Louis, Nundia, Hashizume, Rintaro, Zhang, Peng, Balyasnikova, Irina, Horbinski, Craig, Goldman, Stewart

“…INTRODUCTION: Children with diffuse intrinsic pontine gliomas (DIPGs) die within 2 years after initial diagnosis. The infiltrative nature and anatomic location…”
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ATRT-02. THERAPEUTIC TARGETING OF EZH2 AND BET BRD4 IN AT/RT by Zhang, Ali, Piunti, Andrea, Ozark, Patrick, He, Xingyao, Katagi, Hiroaki, Sasaki, Takahiro, Laurie, Kathryn, Goldman, Stewart, Zou, Lihua, Shilatifard, Ali, Hashizume, Rintaro

“…Abstract Atypical teratoid/rhabdoid tumors (AT/RTs) are lethal childhood cancers and defined by inactivation of the SMARCB1 tumor suppressor gene encoding a…”
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DIPG-24. TARGETED INHIBITION OF JMJD3 AND BET BROMODOMAIN PROTEINS FOR THE TREATMENT OF DIFFUSE INTRINSIC PONTINE GLIOMAS by Katagi, Hiroaki, Louis, Nundia, He, Xingyao, Loughlin, Kathryn, Zhang, Ali, Ozark, Patrick, Horbinski, Craig, Lulla, Rishi, Saratsis, Amanda, Goldman, Stewart, David James, C, Shilatifard, Ali, Hashizume, Rintaro

“…Abstract Recent discovery of somatic histone gene mutations, resulting in replacement of lysine 27 by methionine (K27M) in the encoded histone H3.3 proteins,…”
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PDTM-44. RADIATION DNA DAMAGE REPAIR INHIBITION BY GSK-J4 INDUCED CHROMATIN COMPACTION IN DIPG by Louis, Nundia, He, Xingyao, Piunti, Andrea, Morgan, Marc, Unruh, Dusten, Saratsis, Amanda, Lulla, Rishi, Fangusaro, Jason R, Horbinski, Craig, Goldman, Stewart, James, C David, Shilatifard, Ali, Hashizume, Rintaro

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PDTM-42. TARGETED INHIBITION OF BET BROMODOMAIN AND JMJD3 PROTEINS FOR THE TREATMENT OF DIFFUSE INTRINSIC PONTINE GLIOMA by Katagi, Hiroaki, Zhang, Ali, T. Blyth, Gavin, D. Eckerdt, Frank, A. Ozark, Patrick, Zou, Lihua, He, Xingyao, E. Loughlin, Kathryn, Sasaki, Takahiro, Horbinski, Craig, R. Lulla, Rishi, M. Saratsis, Amanda, Goldman, Stewart, David James, C, Shilatifard, Ali, Hashizume, Rintaro

“…Abstract Recent discovery of somatic histone gene mutations, resulting in replacement of lysine 27 by methionine (K27M) in the encoded histone H3.3 proteins,…”
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PDTM-05. RADIATION DNA DAMAGE REPAIR INHIBITION BY GSK-J4 INDUCED CHROMATIN COMPACTION IN DIPG by Louis, Nundia, Zou, Lihua, Unruh, Dusten, A. Ozark, Patrick, Piunti, Andrea, Gorbunova, Vera, He, Xingyao, Katagi, Hiroaki, Gryzlo, Daniel, Zhang, Ali, M. Saratsis, Amanda, Laurie, Kathryn, Lulla, Rishi, Fangusaro, Jason, Horbinski, Craig, Goldman, Stewart, James, C David, Shilatifard, Ali, Hashizume, Rintaro

“…Abstract INTRODUCTION Focal radiation therapy has long been and remains the only treatment option for diffuse intrinsic pontine glioma (DIPG). However, all…”
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