Search Results - "He, Xiangjun"
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Responses of AOA and AOB activity and DNA/cDNA community structure to allylthiourea exposure in the water level fluctuation zone soil
Published in Environmental science and pollution research international (01-05-2020)“…Ammonia oxidation is mainly performed by ammonia-oxidizing archaea (AOA) and ammonia-oxidizing bacteria (AOB). Allylthiourea (ATU) has been found to…”
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2
Calcium and TRPV4 promote metastasis by regulating cytoskeleton through the RhoA/ROCK1 pathway in endometrial cancer
Published in Cell death & disease (23-11-2020)“…Transient receptor potential vanilloid 4 (TRPV4) is a calcium-permeable cation channel that has been associated with several types of cancer. However, its…”
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3
Long-term effects of chronic exposure to electronic cigarette aerosol on the cardiovascular and pulmonary system in mice: A comparative study to cigarette smoke
Published in Environment international (01-03-2024)“…[Display omitted] Electronic cigarettes (e-cigarettes) have rapidly gained popularity as alternatives to traditional combustible cigarettes. However, their…”
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4
Direct activation of human and mouse Oct4 genes using engineered TALE and Cas9 transcription factors
Published in Nucleic acids research (01-04-2014)“…The newly developed transcription activator-like effector protein (TALE) and clustered regularly interspaced short palindromic repeats/Cas9 transcription…”
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5
Low-dose AAV-CRISPR-mediated liver-specific knock-in restored hemostasis in neonatal hemophilia B mice with subtle antibody response
Published in Nature communications (25-11-2022)“…AAV-delivered CRISPR/Cas9 (AAV-CRISPR) has shown promising potentials in preclinical models to efficiently insert therapeutic gene sequences in somatic…”
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6
Role of steroid receptor-associated and regulated protein in tumor progression and progesterone receptor signaling in endometrial cancer
Published in Chinese medical journal (05-11-2023)“…Steroid receptor-associated and regulated protein (SRARP) suppresses tumor progression and modulates steroid receptor signaling by interacting with estrogen…”
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7
Drought Monitoring from Fengyun Satellite Series: A Comparative Analysis with Meteorological-Drought Composite Index (MCI)
Published in Remote sensing (Basel, Switzerland) (01-11-2023)“…Drought is a complex natural hazard that affects various regions of the world, causing significant economic and environmental losses. Accurate and timely…”
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8
Pharmacokinetics and tissue distribution of bleomycin-induced idiopathic pulmonary fibrosis rats treated with cryptotanshinone
Published in Frontiers in pharmacology (09-03-2023)“…Cryptotanshinone(CTS), a compound derived from the root of , has been linked to various of diseases, particularly pulmonary fibrosis. In the current study, we…”
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Prediction models for postoperative pulmonary complications in intensive care unit patients after noncardiac thoracic surgery
Published in BMC pulmonary medicine (29-08-2024)“…Postoperative pulmonary complication (PPC) is a leading cause of mortality and poor outcomes in postoperative patients. No studies have enrolled intensive care…”
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10
Trypsin inhibitor LH011 inhibited DSS-induced mice colitis via alleviating inflammation and oxidative stress
Published in Frontiers in pharmacology (27-09-2022)“…Background: Ulcerative colitis (UC) is one type of inflammatory bowel disease, characterized by inflammation with infiltration and activation of macrophages in…”
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11
Coupling kinetic modeling with artificial neural networks to predict the kinetic parameters of pine needle pyrolysis
Published in Bioresources (01-11-2024)“…The pyrolysis behavior of biomass is critical for industrial process design, yet the complexity of pyrolysis models makes this task challenging. This paper…”
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12
microRNA-320a inhibits tumor invasion by targeting neuropilin 1 and is associated with liver metastasis in colorectal cancer
Published in Oncology reports (01-03-2012)“…MicroRNAs (miRNAs) have been implicated in regulating diverse cellular pathways. Although there is emerging evidence that various miRNAs function as oncogenes…”
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13
β-catenin mediates endodermal commitment of human ES cells via distinct transactivation functions
Published in Cell & bioscience (24-07-2024)“…β-catenin, acting as the core effector of canonical Wnt signaling pathway, plays a pivotal role in controlling lineage commitment and the formation of…”
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14
Testing multiplexed anti-ASFV CRISPR-Cas9 in reducing African swine fever virus
Published in Microbiology spectrum (02-07-2024)“…African swine fever (ASF) is a highly fatal viral disease that poses a significant threat to domestic pigs and wild boars globally. In our study, we aimed to…”
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15
New Turns for High Efficiency Knock-In of Large DNA in Human Pluripotent Stem Cells
Published in Stem cells international (01-01-2018)“…The groundbreaking CRISPR technology is revolutionizing biomedical research with its superior simplicity, high efficiency, and robust accuracy. Recent…”
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16
Homology-independent multiallelic disruption via CRISPR/Cas9-based knock-in yields distinct functional outcomes in human cells
Published in BMC biology (28-12-2018)“…Cultured human cells are pivotal models to study human gene functions, but introducing complete loss of function in diploid or aneuploid cells has been a…”
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17
Shortening of the 3' untranslated region: an important mechanism leading to overexpression of HMGA2 in serous ovarian cancer
Published in Chinese medical journal (2014)“…Background Oncofetal protein high-mobility-group AT-hook protein 2 (HMGA2) is reactivated in serous ovarian cancer (SOC) and its overexpression correlates with…”
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18
A novel tylophorine analog W-8 up-regulates forkhead boxP3 expression and ameliorates murine colitis
Published in Journal of leukocyte biology (01-01-2013)“…A novel tylophorine analog W‐8 enhanced Foxp3 expression through both transcriptional and epigenetic programs, and its ameliorated TNBS induced colitis…”
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19
The abundance and community structure of active ammonia-oxidizing archaea and ammonia-oxidizing bacteria shape their activities and contributions in coastal wetlands
Published in Water research (Oxford) (15-03-2020)“…Aerobic ammonia oxidation, an important part of the global nitrogen cycle, is thought to be jointly driven by ammonia-oxidizing bacteria (AOB) and…”
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20
Knock-in of large reporter genes in human cells via CRISPR/Cas9-induced homology-dependent and independent DNA repair
Published in Nucleic acids research (19-05-2016)“…CRISPR/Cas9-induced site-specific DNA double-strand breaks (DSBs) can be repaired by homology-directed repair (HDR) or non-homologous end joining (NHEJ)…”
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