Search Results - "He, Wenni"

Antibacterial polyene-polyol macrolides and cyclic peptides from the marine-derived Streptomyces sp. MS110128 by Jiang, Lan, Huang, Pei, Ren, Biao, Song, Zhijun, Zhu, Guoliang, He, Wenni, Zhang, Jingyu, Oyeleye, Ayokunmi, Dai, Huanqin, Zhang, Lixin, Liu, Xueting

“…Marine microbes provide an important resource to discover new chemical compounds with biological activities beneficial to drug discovery. In our study, two new…”
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New butyrolactone derivatives from the endophytic Fungus Talaromyces sp. CPCC 400783 of Reynoutria japonica Houtt by Zhang, Ran, He, Wenni, Wang, Yujia, Zhao, JianYuan, Zhou, Rui, Li, Li, He, Yize, Cen, Shan, Yu, Liyan

“…Six new butyrolactone derivatives ( 1, 2a/2b, 3a/3b and 4 ), together with another two known derivatives ( 5 and 6 ) were isolated from the endophytic fungus…”
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Abyssomicins from the South China Sea Deep-Sea Sediment Verrucosispora sp.: Natural Thioether Michael Addition Adducts as Antitubercular Prodrugs by Wang, Qian, Song, Fuhang, Xiao, Xue, Huang, Pei, Li, Li, Monte, Aaron, Abdel-Mageed, Wael M., Wang, Jian, Guo, Hui, He, Wenni, Xie, Feng, Dai, Huanqin, Liu, Miaomiao, Chen, Caixia, Xu, Hao, Liu, Mei, Piggott, Andrew M., Liu, Xueting, Capon, Robert J., Zhang, Lixin

“…From the deep: The title actinomycete yielded three new abyssomicins J–L. The dimeric thioether J (see scheme) represents a unique example of a masked Michael…”
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Mining and characterization of the PKS–NRPS hybrid for epicoccamide A: a mannosylated tetramate derivative from Epicoccum sp. CPCC 400996 by Zhang, Tao, Cai, Guowei, Rong, Xiaoting, Xu, Jingwen, Jiang, Bingya, Wang, Hao, Li, Xinxin, Wang, Lu, Zhang, Ran, He, Wenni, Yu, Liyan

“…Abstract Background Genomic analysis indicated that the genomes of ascomycetes might carry dozens of biosynthetic gene clusters (BGCs), yet many clusters have…”
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Brochoscopic Airway Clearance Therapy vs. Conventional Sputum Aspiration: The Future of Flexible Brochoscopes in Intensive Care Units? by Yao, Anjie, Liu, Zixuan, He, Wenni, Rao, Hanyu, Wang, Changhui, Xie, Shuanshuan

“…(1) Background: The aim of our study is to investigate the effectiveness of bronchoscopic airway clearance therapy (B-ACT) on severe pneumonia (SP) patients…”
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Genomic and Transcriptomic Approaches Provide a Predictive Framework for Sesquiterpenes Biosynthesis in Desarmillaria tabescens CPCC 401429 by Zhang, Tao, Feng, Jianjv, He, Wenni, Rong, Xiaoting, Lv, Hui, Li, Jun, Li, Xinxin, Wang, Hao, Wang, Lu, Zhang, Lixin, Yu, Liyan

“…Terpenoids constitute a structurally diverse class of secondary metabolites with wide applications in the pharmaceutical, fragrance and flavor industries. CPCC…”
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Exploring anti-TB leads from natural products library originated from marine microbes and medicinal plants by Liu, Xueting, Chen, Caixia, He, Wenni, Huang, Pei, Liu, Miaomiao, Wang, Qian, Guo, Hui, Bolla, Krishna, Lu, Yan, Song, Fuhang, Dai, Huanqin, Liu, Mei, Zhang, Lixin

“…Multidrug-resistant tuberculosis (MDR-TB) and TB–HIV co-infection have become a great threat to global health. However, the last truly novel drug that was…”
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Discovery of tanshinone derivatives with anti-MRSA activity via targeted bio-transformation by He, Wenni, Liu, Miaomiao, Huang, Pei, Abdel-Mageed, Wael M., Han, Jianying, Watrous, Jeramie D., Nguyen, Don D., Wang, Wenzhao, Song, Fuhang, Dai, Huanqin, Zhang, Jingyu, Quinn, Ronald J., Grkovi, Tanja, Luo, Houwei, Zhang, Lixin, Liu, Xueting

“…Two potent anti-MRSA tanshinone glycosides (1 and 2) were discovered by targeted microbial biotransformation, along with rapid identification via MS/MS…”
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Exploration of diverse secondary metabolites from Penicillium brasilianum by co-culturing with Armillaria mellea by Rong, Xiaoting, Zhang, Lihua, He, Wenni, Guo, Zhe, Lv, Hui, Bai, Jinglin, Yu, Liyan, Zhang, Lixin, Zhang, Tao

“…Bioinformatic analysis revealed that the genomes of ubiquitous Penicillium spp. might carry dozens of biosynthetic gene clusters (BGCs), yet many clusters have…”
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Subplenones A-J: Dimeric Xanthones with Antibacterial Activity from the Endophytic Fungus Subplenodomus sp. CPCC 401465 by Cai, Guowei, Hu, Xinxin, Zhang, Ran, Wang, JuXian, Fang, Xiaomei, Pang, Xu, Bai, Jinglin, Zhang, Tao, Zhang, Tao, Lv, Hui, You, Xuefu, He, Wenni, Yu, Liyan

“…Subplenones A-J ( - ), 10 new xanthone dimers, have been isolated and characterized from the endophytic fungus sp. CPCC 401465, which resides within the…”
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Verbalide A~F: new phthalide derivatives from the endophytic fungus Preussia sp. CPCC 400972 by Zhang, Ran, Wang, Yujia, Cai, Guowei, Wang, Juxian, Zhao, Jianyuan, Bai, Jinglin, Zhang, Tao, Cen, Shan, He, Wenni, Yu, Liyan

“…There are six new phthalide derivatives Verbalide A ~ F ( 1 – 6 ) together with another known derivative ( 7 ) isolated from the endophytic fungus Preussia sp…”
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Discovery and Activation of the Cryptic Cluster from Aspergillus sp. CPCC 400735 for Asperphenalenone Biosynthesis by Zhang, Tao, Pang, Xu, Zhao, Jianyuan, Guo, Zhe, He, Wenni, Cai, Guowei, Su, Jing, Cen, Shan, Yu, Liyan

“…Postgenomic analysis manifested that filamentous fungi contain numerous natural product biosynthetic gene clusters in their genome, yet most clusters remain…”
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New cryptotanshinone derivatives with anti-influenza A virus activities obtained via biotransformation by Mucor rouxii by He, Wenni, Li, Yao, Qin, Yuejie, Tong, Xiaomei, Song, Zhijun, Zhao, Yu, Wei, Ran, Li, Li, Dai, Huanqin, Wang, Wenzhao, Luo, Houwei, Ye, Xin, Zhang, Lixin, Liu, Xueting

“…This paper provides an efficient platform to diversify the structure and pharmaceutical potentials of known natural products. Seven metabolites were obtained…”
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Efficient biocatalysis of trillin through recombinant enzyme hydrolysis for clean diosgenin production by Liu, Wancang, Xiang, Haibo, Shiloach, Joseph, Zhang, Tao, He, Wenni, Pang, Xu, Su, Jing, Liu, Hongyu, Ma, Baiping, Yu, Liyan

“…[Display omitted] Diosgenin has been widely used as a precursor in the pharmaceutical industry. The conventional diosgenin production method, direct acid…”
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Caesanines A–D, New Cassane Diterpenes with Unprecedented N Bridge from Caesalpinia sappan by Zhang, Jingyu, Abdel-Mageed, Wael M, Liu, Miaomiao, Huang, Pei, He, Wenni, Li, Li, Song, Fuhang, Dai, Huanqin, Liu, Xueting, Liang, Jingyu, Zhang, Lixin

“…Serial antibacterial furanoditerpenes caesanines A–D (1–4), possessing a cassane-type diterpenoid skeleton with an unusual N bridge between C-19/C-20, were…”
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Genomic and Transcriptomic Approaches Provide a Predictive Framework for Sesquiterpenes Biosynthesis in IDesarmillaria tabescens/I CPCC 401429 by Zhang, Tao, Feng, Jianjv, He, Wenni, Rong, Xiaoting, Lv, Hui, Li, Jun, Li, Xinxin, Wang, Hao, Wang, Lu, Zhang, Lixin, Yu, Liyan

“…Terpenoids constitute a structurally diverse class of secondary metabolites with wide applications in the pharmaceutical, fragrance and flavor industries…”
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Bioassay-guided identification of bioactive molecules from traditional Chinese medicines by Han, Jianying, Zhang, Jingyu, He, Wenni, Huang, Pei, Oyeleye, Ayokunmi, Liu, Xueting, Zhang, Lixin

“…Traditional Chinese medicines (TCMs) serve as a major source of a variety of drug lead compounds. In the process of natural products development,…”
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Fungal biotransformation of tanshinone results in [4+2] cycloaddition with sorbicillinol: evidence for enzyme catalysis and increased antibacterial activity by He, Wenni, Liu, Miaomiao, Li, Xiaolin, Zhang, Xiaoping, Abdel-Mageed, Wael M., Li, Li, Wang, Wenzhao, Zhang, Jingyu, Han, Jianying, Dai, Huanqin, Quinn, Ronald J., Liu, Hung-wen, Luo, Houwei, Zhang, Lixin, Liu, Xueting

“…The biotransformation of tanshinone IIA to a new antibacterial agent tanshisorbicin ( 1 ) by the fungus Hypocrea sp. (AS 3.17108) is described. The structure…”
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Endophytic Streptomyces sp. Y3111 from traditional Chinese medicine produced antitubercular pluramycins by Liu, Miaomiao, Abdel-Mageed, Wael M, Ren, Biao, He, Wenni, Huang, Pei, Li, Xiaolin, Bolla, Krishna, Guo, Hui, Chen, Caixia, Song, Fuhang, Dai, Huanqin, Quinn, Ronald J, Grkovic, Tanja, Zhang, Xiaoping, Liu, Xueting, Zhang, Lixin

“…As part of a search for antitubercular substances from natural sources, we screened a library of endophytic microbes (50 strains and 300 crude extracts in…”
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Abyssomicins from the South China Sea Deep-Sea Sediment Verrucosispora sp.: Natural Thioether Michael Addition Adducts as Antitubercular Prodrugs by Wang, Qian, Song, Fuhang, Xiao, Xue, Huang, Pei, Li, Li, Monte, Aaron, Abdel-Mageed, Wael M., Wang, Jian, Guo, Hui, He, Wenni, Xie, Feng, Dai, Huanqin, Liu, Miaomiao, Chen, Caixia, Xu, Hao, Liu, Mei, Piggott, Andrew M., Liu, Xueting, Capon, Robert J., Zhang, Lixin

“…Aus der Tiefe: Aus dem Titelactinomyceten wurden die drei neue Abyssomicine J–L isoliert. Der dimere Thioether J (siehe Schema) ist ein einzigartiges Beispiel…”
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