Search Results - "He, Weijiang"
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H2O2‑Activatable and O2‑Evolving Nanoparticles for Highly Efficient and Selective Photodynamic Therapy against Hypoxic Tumor Cells
Published in Journal of the American Chemical Society (04-02-2015)“…The low selectivity of currently available photosensitizers, which causes the treatment-related toxicity and side effects on adjacent normal tissues, is a…”
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2
A dual-labeling probe to track functional mitochondria–lysosome interactions in live cells
Published in Nature communications (08-12-2020)“…Mitochondria–lysosome interactions are essential for maintaining intracellular homeostasis. Although various fluorescent probes have been developed to…”
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3
An Optical/Photoacoustic Dual-Modality Probe: Ratiometric in/ex Vivo Imaging for Stimulated H2S Upregulation in Mice
Published in Journal of the American Chemical Society (13-11-2019)“…Tracking signaling H2S in live mice demands responsive imaging with fine tissue imaging depth and low interferences from tissue scattering/autofluorescence and…”
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4
Golgi apparatus-targeted aggregation-induced emission luminogens for effective cancer photodynamic therapy
Published in Nature communications (21-04-2022)“…Golgi apparatus (GA) oxidative stress induced by in situ reactive oxygen species (ROS) could severely damage the morphology and function of GA, which may open…”
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Simultaneous Zn2+ tracking in multiple organelles using super-resolution morphology-correlated organelle identification in living cells
Published in Nature communications (04-01-2021)“…Zn 2+ plays important roles in metabolism and signaling regulation. Subcellular Zn 2+ compartmentalization is essential for organelle functions and cell…”
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A Ratiometric Fluorescent Probe for Rapid Detection of Hydrogen Sulfide in Mitochondria
Published in Angewandte Chemie International Edition (04-02-2013)“…Quick: An exogenously induced quick increase of the H2S concentration (80 s) in MCF‐7 cells can be visualized by ratiometric imaging using a new probe (CouMC)…”
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7
Rational construction of a reversible arylazo-based NIR probe for cycling hypoxia imaging in vivo
Published in Nature communications (13-05-2021)“…Reversible NIR luminescent probes with negligible photocytotoxicity are required for long-term tracking of cycling hypoxia in vivo. However, almost all of the…”
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8
Rational Design of a Dual Chemosensor for Cyanide Anion Sensing Based on Dicyanovinyl-Substituted Benzofurazan
Published in Journal of organic chemistry (16-12-2011)“…A dicyanovinyl-substituted benzofurazan derivative (C1) was prepared as an efficient ratiometric chemosensor for cyanide anion detection in aqueous…”
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9
A coordinate-based meta-analysis of the n-back working memory paradigm using activation likelihood estimation
Published in Brain and cognition (01-06-2019)“…•Data was pooled from 96 studies of n-back (120 experiments and 2846 subjects).•The results showed consistent activation of the frontal-parietal cortices and…”
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Visible Light Excitable Zn2+ Fluorescent Sensor Derived from an Intramolecular Charge Transfer Fluorophore and Its in Vitro and in Vivo Application
Published in Journal of the American Chemical Society (04-02-2009)“…The UV- and sensor-induced interferences to living systems pose a barrier for in vivo Zn2+ imaging. In this work, an intramolecular charge transfer (ICT)…”
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An H₂O₂-responsive nanocarrier for dual-release of platinum anticancer drugs and O₂: controlled release and enhanced cytotoxicity against cisplatin resistant cancer cells
Published in Chemical communications (Cambridge, England) (04-09-2014)“…Synergistic release of platinum anticancer drugs and O2 can be achieved in an H2O2-responsive nanocarrier incorporated with catalase. Such a system combines…”
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12
Nanoscale monitoring of mitochondria and lysosome interactions for drug screening and discovery
Published in Nano research (01-05-2019)“…Technology advances in genomics, proteomics, and metabolomics largely expanded the pool of potential therapeutic targets. Compared with the in vitro setting,…”
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13
Piezochromic luminescence behaviors of two new benzothiazole-enamido boron difluoride complexes: intra- and inter-molecular effects induced by hydrostatic compression
Published in Chemical communications (Cambridge, England) (01-05-2015)“…Two new propeller-shaped benzothiazole-enamide boron difluoride complexes exhibiting piezochromic luminescence upon mechanical grinding or hydrostatic…”
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14
Noncovalent Interactions between a Trinuclear Monofunctional Platinum Complex and Human Serum Albumin
Published in Inorganic chemistry (19-12-2011)“…Interactions between platinum complexes and human serum albumin (HSA) play crucial roles in the metabolism, distribution, and efficacy of platinum-based…”
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15
A Near-Infrared Fluorescent and Photoacoustic Probe for Visualizing Biothiols Dynamics in Tumor and Liver
Published in Molecules (Basel, Switzerland) (27-02-2023)“…Biothiols, including glutathione (GSH), homocysteine (Hcy) and cysteine (Cys), play crucial roles in various physiological processes. Though an array of…”
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16
A highly sensitive ratiometric fluorescent probe for Cd2+ detection in aqueous solution and living cells
Published in Chemical communications (Cambridge, England) (01-01-2010)“…A ratiometric fluorescent Cd(2+) sensor DBITA which featured the Cd(2+)-induced red-shift of emission (53 nm) and picomolar sensitivity in both aqueous media…”
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Manipulating the Subcellular Localization and Anticancer Effects of Benzophenothiaziniums by Minor Alterations of N-Alkylation
Published in Molecules (Basel, Switzerland) (01-02-2023)“…Cationic, water-soluble benzophenothiaziniums have been recognized as effective type I photosensitizers (PSs) against hypoxic tumor cells. However, the study…”
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18
A new ratiometric and colorimetric chemosensor for cyanide anion based on coumarin-hemicyanine hybrid
Published in Organic & biomolecular chemistry (14-07-2012)“…A hybrid coumarin-hemicyanine dye, Cou-BT, was developed as a new ratiometric and colorimetric sensor for cyanide with a sensing mechanism via nucleophilic…”
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19
High solid-state luminescence in propeller-shaped AIE-active pyridine-ketoiminate-boron complexes
Published in Organic & biomolecular chemistry (28-05-2015)“…Two pyridine-ketoiminate-based organoboron complexes (2 and 3) were developed. 2 and 3 showed very weak emission in low-viscosity organic solvents because of…”
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An Endoplasmic Reticulum-Targeted Ratiometric Fluorescent Molecule Reveals Zn2+ Micro-Dynamics During Drug-Induced Organelle Ionic Disorder
Published in Frontiers in pharmacology (06-06-2022)“…The endoplasmic reticulum (ER) is the main storage site of Zn 2+ , and Zn 2+ plays an important role in regulating ER homeostasis. Therefore, we designed and…”
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