Search Results - "He, Wei‐wu"
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Elevation of TP53 Autoantibody Before CA125 in Preclinical Invasive Epithelial Ovarian Cancer
Published in Clinical cancer research (01-10-2017)“…The tumor-suppressor gene is mutated in >95% of high-grade serous ovarian cancers. Detecting an autologous antibody response to TP53 that might improve early…”
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TMEM163 Regulates ATP-Gated P2X Receptor and Behavior
Published in Cell reports (Cambridge) (02-06-2020)“…Fast purinergic signaling is mediated by ATP and ATP-gated ionotropic P2X receptors (P2XRs), and it is implicated in pain-related behaviors. The properties…”
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Application of Active and Kinase-Deficient Kinome Collection for Identification of Kinases Regulating Hedgehog Signaling
Published in Cell (02-05-2008)“…To allow genome-scale identification of genes that regulate cellular signaling, we cloned >90% of all human full-length protein kinase cDNAs and constructed…”
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Using protein microarray technology to screen anti-ERCC1 monoclonal antibodies for specificity and applications in pathology
Published in BMC biotechnology (21-11-2012)“…An antibody with cross-reactivity can create unexpected side effects or false diagnostic reports if used for clinical purposes. ERCC1 is being explored as a…”
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Expression and Characterization of Human Fragile X Mental Retardation Protein Isoforms and Interacting Proteins in Human Cells
Published in Proteomics insights (2019)“…Fragile X mental retardation protein is an mRNA-binding protein associated with phenotypic manifestations of fragile X syndrome, an X-linked disorder caused by…”
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Cloning, expression and chromosome locations of the human DNMT3 gene family
Published in Gene (05-08-1999)“…DNA methylation plays an important role in animal development and gene regulation. In mammals, several genes encoding DNA cytosine methyltransferases have been…”
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Tpl2/AP-1 Enhances Murine Gammaherpesvirus 68 Lytic Replication
Published in Journal of Virology (01-02-2010)“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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ICE-LAP3, a Novel Mammalian Homologue of the Caenorhabditis elegans Cell Death Protein Ced-3 Is Activated during Fas- and Tumor Necrosis Factor-induced Apoptosis (∗)
Published in The Journal of biological chemistry (19-01-1996)“…Members of the ICE/ced-3 gene family have been implicated as components of the cell death pathway. Based on similarities with the structural prototype…”
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ICE-LAP6, a Novel Member of the ICE/Ced-3 Gene Family, Is Activated by the Cytotoxic T Cell Protease Granzyme B
Published in The Journal of biological chemistry (12-07-1996)“…Members of the ICE/Ced-3 gene family are likely effector components of the cell death machinery. Here, we characterize a novel member of this family designated…”
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Prostate-specific and Androgen-dependent Expression of a Novel Homeobox Gene
Published in The Journal of biological chemistry (13-12-1996)“…A new member of the mouse NK family of homeobox genes that is related to Drosophila NK-3 has been identified. Expression of this gene, termed Nkx-3.1, is…”
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c-IAP1 Is Cleaved by Caspases to Produce a Proapoptotic C-terminal Fragment
Published in The Journal of biological chemistry (09-03-2001)“…Although human c-IAP1 and c-IAP2 have been reported to possess antiapoptotic activity against a variety of stimuli in several mammalian cell types, we observed…”
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A pathway sensor for genome-wide screens of intracellular proteolytic cleavage
Published in Genome biology (03-04-2008)“…Protein cleavage is a central event in many regulated biological processes. We describe a system for detecting intracellular proteolysis based on…”
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Glial‐derived nexin, a differentially expressed gene during neuronal differentiation, transforms HEK cells into neuron‐like cells
Published in International journal of developmental neuroscience (01-02-2005)“…Glial‐derived nexin (GDN) is a proteinase inhibitor secreted from glial cells and it can enhance neuronal function. However, its expression and function in…”
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Mullerian inhibiting substance messenger ribonucleic acid expression in granulosa and Sertoli cells coincides with their mitotic activity
Published in Endocrinology (Philadelphia) (01-08-1992)“…In males, Mullerian inhibiting substance (MIS) mRNA was first detected on the medial aspect of the urogenital ridge early on the morning of day 13 of gestation…”
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Reed-Sternberg cell genome expression supports a B-cell lineage
Published in Blood (15-07-1999)“…The malignant Reed-Sternberg cell of Hodgkin's disease, first described a century ago, has resisted in-depth analysis due to its extreme rarity in lymphomatous…”
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Ginkgo biloba extract (EGb 761) attenuates lung injury induced by intestinal ischemia/reperfusion in rats: Roles of oxidative stress and nitric oxide
Published in World journal of gastroenterology : WJG (2007)“…AIM: To investigate the effect of ginkgo biloba extract (EGb 761) on lung injury induced by intestinal ischemia/ reperfusion ( Ⅱ/R). METHODS: The rat model of…”
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AF1q, a differentially expressed gene during neuronal differentiation, transforms HEK cells into neuron-like cells
Published in Brain research. Molecular brain research. (24-11-2004)“…Three cell groups, neural stem/progenitor cells (NS/PCs) dissociated from the embryonic day 11 (E11) rodent cerebral cortex, expanded NS/PC cultures, and…”
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ARDD 2020: from aging mechanisms to interventions
Published in Aging (Albany, NY.) (30-12-2020)“…Aging is emerging as a druggable target with growing interest from academia, industry and investors. New technologies such as artificial intelligence and…”
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Abstract 561: Development of a highly specific Met antibody for screening Met overexpression in NSCLC
Published in Cancer research (Chicago, Ill.) (01-08-2015)“…Approximately 5%-22% of non-small cell lung cancer (NSCLC) patients with secondary resistance to EGFR TKIs had evidence of amplification of the Met oncogene…”
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Abstract 3216: Using protein microarray technology to develop mono-specific anti-ERCC1 mAbs for anatomic pathology applications
Published in Cancer research (Chicago, Ill.) (15-04-2013)“…Antibody with cross-reactivity can create unexpected side effects or false diagnostic reports if used for clinical purposes. ERCC1 is a predictive biomarker…”
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