Search Results - "He, Qunye"
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Metal-organic frameworks for stimuli-responsive drug delivery
Published in Biomaterials (01-02-2020)“…Metal-organic framework (MOF), a novel hybrid porous material which is composited by metal ions and organic linkers, has drawn increasing attention and became…”
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Cancer protein biomarker discovery based on nucleic acid aptamers
Published in International journal of biological macromolecules (01-07-2019)“…Identification of biomarkers is essential for diagnosis, targeted therapy and prognosis evaluation of diseases, especially cancers. Currently, the number of…”
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Tumor microenvironment responsive drug delivery systems
Published in Asian journal of pharmceutical sciences (01-07-2020)“…Conventional tumor-targeted drug delivery systems (DDSs) face challenges, such as unsatisfied systemic circulation, low targeting efficiency, poor tumoral…”
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4
Dynamic DNA Assemblies in Biomedical Applications
Published in Advanced science (01-07-2020)“…Deoxyribonucleic acid (DNA) has been widely used to construct homogeneous structures with increasing complexity for biological and biomedical applications due…”
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The immunotoxin targeting PRLR increases tamoxifen sensitivity and enhances the efficacy of chemotherapy in breast cancer
Published in Journal of experimental & clinical cancer research (20-06-2024)“…Though tamoxifen achieves success in treating estrogen receptor α (ERα)-positive breast cancer, the followed development of tamoxifen resistance is a common…”
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Advances in aptamer screening technologies
Published in Talanta (Oxford) (01-08-2019)“…Systematic evolution of ligands by exponential enrichment (SELEX) is a well-established technology for the screening of aptamers binding to various targets…”
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Metal-organic frameworks for virus detection
Published in Biosensors & bioelectronics (01-12-2020)“…Virus severely endangers human life and health, and the detection of viruses is essential for the prevention and treatment of associated diseases…”
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Dynamic DNA Nanostructures for Cell Manipulation
Published in ACS biomaterials science & engineering (13-02-2023)“…Dynamic DNA nanostructures are DNA nanostructures with reconfigurable elements that can undergo structural transformations in response to specific stimuli…”
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Interfacing DNA with nanoparticles: Surface science and its applications in biosensing
Published in International journal of biological macromolecules (15-05-2020)“…The knowledge on the mechanisms of DNA interfacing with nanoparticles holds great potential for the design, assembly and usage of DNA in biological…”
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Aptamer–Pyropheophorbide a Conjugates with Tumor Spheroid Targeting and Penetration Abilities for Photodynamic Therapy
Published in Molecular pharmaceutics (03-08-2020)“…Pyropheophorbide a (Pyro) is a widely used photosensitizer for photodynamic therapy (PDT). However, poor water solubility, aggregation-induced fluorescence…”
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Supramolecular antibody-drug conjugates for combined antibody therapy and photothermal therapy targeting HER2-positive cancers
Published in International journal of biological macromolecules (01-10-2024)“…Antibody therapy of anti-HER2 monoclonal antibody (mAb) has been an important strategy in treating HER2-positive cancers. However, the efficacy is restricted…”
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Single-Cell Landscape and a Macrophage Subset Enhancing Brown Adipocyte Function in Diabetes
Published in Diabetes & metabolism journal (30-09-2024)“…Metabolic dysregulation is a hallmark of type 2 diabetes mellitus (T2DM), in which the abnormalities in brown adipose tissue (BAT) play important roles…”
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