Search Results - "He, Maotao"

Prenatal GABAB Receptor Agonist Administration Corrects the Inheritance of Autism-Like Core Behaviors in Offspring of Mice Prenatally Exposed to Valproic Acid by Jiang, Shucai, He, Maotao, Xiao, Lifei, Sun, Yu, Ding, Jiangwei, Li, Wenchao, Guo, Baorui, Wang, Lei, Wang, Yangyang, Gao, Caibin, Sun, Tao, Wang, Feng

“…This study was performed to evaluate the effects of prenatal baclofen (a GABAB receptor agonist) treatment on the inheritance of autism-like behaviors in…”
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Deletion of Mitochondrial Uncoupling Protein 2 Exacerbates Mitochondrial Damage in Mice Subjected to Cerebral Ischemia and Reperfusion Injury under both Normo- and Hyperglycemic Conditions by He, Maotao, Ma, Yanmei, Wang, Rui, Zhang, Jianzhong, Jing, Li, Li, P Andy

“…Deletion of mitochondrial uncoupling protein 2 (UCP2) has been shown to aggravate ischemic damage in the brain. However, the underlying mechanisms are not…”
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Repurposed genipin targeting UCP2 exhibits antitumor activity through inducing ferroptosis in glioblastoma by Dong, Hao, Sun, Kaixuan, Wang, Xuejie, Cui, Meimei, Ma, Yaping, Li, Kexin, Duan, Wanli, Zhang, Hongxing, Zhang, Liying, Sheng, Zhimei, He, Maotao, Zhang, Baogang

“…Uncoupling protein-2 (UCP2) controls the antioxidant response and redox homeostasis in cancer and is considered a potent molecular target for cancer treatment…”
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A plant-based mutant huntingtin model-driven discovery of impaired expression of GTPCH and DHFR by Hung, Chiu-Yueh, Zhu, Chuanshu, Kittur, Farooqahmed S., He, Maotao, Arning, Erland, Zhang, Jianhui, Johnson, Asia J., Jawa, Gurpreet S., Thomas, Michelle D., Ding, Tomas T., Xie, Jiahua

“…Pathophysiology associated with Huntington’s disease (HD) has been studied extensively in various cell and animal models since the 1993 discovery of the mutant…”
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The GABAB receptor agonist STX209 reverses the autism‑like behaviour in an animal model of autism induced by prenatal exposure to valproic acid by Jiang, Shucai, Xiao, Lifei, Sun, Yu, He, Maotao, Gao, Caibin, Zhu, Changliang, Chang, Haigang, Ding, Jiangwei, Li, Wenchao, Wang, Yangyang, Sun, Tao, Wang, Feng

“…Autism spectrum disorder (ASD) is a lifelong neurodevelopmental condition characterized by impaired social interaction, compromised communication, and…”
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Abstract 4595: HSK41959-2: An oral MTA-cooperative PRMT5 inhibitor for MTAP deleted cancer by Yan, Pangke, Wang, Ju, Qian, Meilin, Yu, Xiaojuan, Li, Yao, Zhang, Haoliang, Tao, Lihua, Kou, Rui, Hu, Teng, Tang, Pingming, Dong, Hongjiao, Wu, Aipin, He, Maotao

“…Methylthioadenosine phosphorylase (MTAP) homozygous deletion occurs in 10-15% of all human cancers. Loss of MTAP result in methylthioadenosine (MTA)…”
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A Novel Plant-Produced Asialo-rhuEPO Protects Brain from Ischemic Damage Without Erythropoietic Action by He, Maotao, Kittur, Farooqahmed S., Hung, Chiu-Yueh, Zhang, Jianhui, Jing, Li, Sane, David C., Li, P. Andy, Xie, Jiahua

“…Mammalian cell-produced recombinant human erythropoietin (rhuEPO M ) has been shown to be a multimodal neuroprotectant targeting an array of key pathological…”
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Abstract LB262: HSK38008: An oral AR-V7 degrader for metastatic castration-resistant prostate cancer by Wang, Ju, Qian, Meilin, Yan, Pangke, Li, Linli, Zhang, Chen, Yu, Yan, Tao, Lihua, Tang, Pingming, Liao, Yuting, Chen, Xiaogang, Cheng, Xinfan, Xu, Jinxiong, Wan, Xuemei, Deng, Luchan, Dong, Hongjiao, Zhang, Haixian, He, Maotao

“…The androgen deprivation therapy (ADT) alone and its combination with hormone therapy that block AR signaling (e.g., enzalutamide or abiraterone) are effective…”
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Deletion of mitochondrial uncoupling protein 2 exacerbates mitophagy and cell apoptosis after cerebral ischemia and reperfusion injury in mice by He, Maotao, Zhang, Ting, Fan, Yucheng, Ma, Yanmei, Zhang, Jianzhong, Jing, Li, Li, P. Andy

“…Objective: Uncoupling protein 2 (UCP2) is a member of inner mitochondrial membrane proteins and deletion of UCP2 exacerbates brain damage after cerebral…”
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