Search Results - "He, Manman"
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An enzyme-initiated DNAzyme motor for RNase H activity imaging in living cell
Published in Chemical communications (Cambridge, England) (14-01-2020)“…In this work, we have developed a novel DNAzyme motor initiated by endogenous enzyme for sensitive imaging of intracellular RNase H activity…”
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2
Purification and characterization of alginate lyase from Sphingomonas sp. ZH0
Published in Journal of bioscience and bioengineering (01-09-2018)“…Alginate lyases degrade alginate in a beta-elimination reaction to produce oligosaccharides. Thus, alginate lyases are widely used in the food/pharmaceutical…”
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3
A global screening identifies chromatin-enriched RNA-binding proteins and the transcriptional regulatory activity of QKI5 during monocytic differentiation
Published in Genome Biology (14-10-2021)“…Cellular RNA-binding proteins (RBPs) have multiple roles in post-transcriptional control, and some are shown to bind DNA. However, the global localization and…”
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Biomineralized synthesis of luminescent protease-(NH4)2Y3F11•H2O hybrid nanospheres and their applications as a stable and reusable enzyme reactor
Published in Collagen and Leather (01-12-2024)“…Proteases, such as trypsin, are essential for extracting collagen in various industrial applications. The potential applications of rare earth nanomaterials,…”
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A multi-objective ant colony optimization with decomposition for community detection in complex networks
Published in Transactions of the Institute of Measurement and Control (01-06-2019)“…Community detection in complex networks plays an important role in mining and analyzing the structure and function of networks. However, traditional algorithms…”
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6
Luminescent Biofunctional Collagen Mimetic Nanofibers
Published in ACS omega (08-10-2019)“…Collagen has long been one of the top targets for biomimetic design due to its superior structural and functional properties. Significant progress has been…”
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Deciphering the Functional Long Non‐Coding RNAs Derived from MicroRNA Loci
Published in Advanced science (01-11-2023)“…Albeit the majority of eukaryotic genomes can be pervasively transcribed to a diverse population of lncRNAs and various subtypes of lncRNA are discovered…”
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Aptamer-Functionalized DNA Origami for Targeted Codelivery of Antisense Oligonucleotides and Doxorubicin to Enhance Therapy in Drug-Resistant Cancer Cells
Published in ACS applied materials & interfaces (08-01-2020)“…Drug resistance is a major obstacle to the efficient therapy of drug-resistant cancer. To overcome this problem, we constructed a multifunctional DNA…”
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Biomineralized Metal–Organic Framework Nanoparticles Enable Enzymatic Rolling Circle Amplification in Living Cells for Ultrasensitive MicroRNA Imaging
Published in Analytical chemistry (Washington) (16-07-2019)“…The enzymatic amplification strategy in living cells faces challenges of highly efficient intracellular codelivery of amplification reagents including DNA…”
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Biomineralized metal-organic framework nanoparticles enable a primer exchange reaction-based DNA machine to work in living cells for imaging and gene therapy
Published in Chemical science (Cambridge) (21-07-2020)“…Sensitive tumor imaging and precise tumor therapy play critical roles in the cancer combat. Herein, we build a DNA machine based on a primer exchange reaction…”
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Erythrocyte-Membrane-Enveloped Biomineralized Metal–Organic Framework Nanoparticles Enable Intravenous Glucose-Responsive Insulin Delivery
Published in ACS applied materials & interfaces (05-05-2021)“…A “closed-loop” insulin delivery system that can mimic the dynamic and glucose-responsive insulin secretion as islet β-cells is desirable for the therapy of…”
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12
mRNA-Activated Multifunctional DNAzyme Nanotweezer for Intracellular mRNA Sensing and Gene Therapy
Published in ACS applied materials & interfaces (24-02-2021)“…Deoxyribozyme (DNAzyme) is regarded as a promising gene therapy drug. However, poor cellular uptake efficacy and low biological stability limit the utilization…”
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A microRNA-triggered self-powered DNAzyme walker operating in living cells
Published in Biosensors & bioelectronics (01-07-2019)“…DNA-based nanomachines have received increasing attention due to their great potential to mimic natural biological motors and create novel modes of motion…”
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Fabrication and characterization of BiOBr:Yb3+,Er3+/g-C3N4 p-n junction photocatalysts with enhanced visible-NIR-light-driven photoactivities
Published in Separation and purification technology (29-11-2018)“…•BYE/CN photocatalysts exhibit improved visible and NIR photoactivity.•The improved activity is due to the Er3+ up-conversion and formation of p-n…”
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Covalently-bonded single-site Ru-N2 knitted into covalent triazine frameworks for boosting photocatalytic CO2 reduction
Published in Applied catalysis. B, Environmental (01-03-2023)“…Harvesting solar energy to convert CO2 into chemicals via photocatalysis has received increasing attention, however, lack of precisely controlled and uniformly…”
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Bioethanol production from sodium hydroxide/hydrogen peroxide-pretreated water hyacinth via simultaneous saccharification and fermentation with a newly isolated thermotolerant Kluyveromyces marxianu strain
Published in Bioresource technology (01-10-2015)“…•H2O2/NaOH pretreatment of water hyacinth at mild conditions is effective.•A newly isolated K213 showed higher ethanol production from glucose at 42°C.•K213…”
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Experimental Study on Influence of Disc Number on Soil Failure State of Concrete Expanded-Plate Pile under Horizontal Force in Oceanographic Engineering
Published in Journal of coastal research (01-06-2020)“…Qian, Y.; He, M., and Wang, R., 2020. Experimental study on influence of disc number on soil failure state of concrete expanded-plate pile under horizontal…”
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METTL3 preferentially enhances non-m6A translation of epigenetic factors and promotes tumourigenesis
Published in Nature cell biology (01-08-2022)“…METTL3 encodes the predominant catalytic enzyme to promote m 6 A methylation in nucleus. Recently, accumulating evidence has shown the expression of METTL3 in…”
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A spatial-confinement hairpin cascade reaction-based DNA tetrahedral amplifier for mRNA imaging in live cells
Published in Talanta (Oxford) (15-01-2020)“…The three-dimensional (3D) DNA nanostructure has been got much attention due to its excellent biocompatibility, enhanced structural stability, highly…”
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A comprehensive RNA editome reveals that edited Azin1 partners with DDX1 to enable hematopoietic stem cell differentiation
Published in Blood (18-11-2021)“…Adenosine-to-inosine RNA editing and the catalyzing enzyme adenosine deaminase are both essential for hematopoietic development and differentiation. However,…”
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