Search Results - "He, Liuer"
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Functions of N6-methyladenosine and its role in cancer
Published in Molecular cancer (04-12-2019)“…N6-methyladenosine (m6A) is methylation that occurs in the N6-position of adenosine, which is the most prevalent internal modification on eukaryotic mRNA…”
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Case report: MSI-H, EGFR mutation, and ground-glass nodules as diffuse pulmonary hematogenous metastases
Published in Frontiers in immunology (28-10-2024)“…Ground-glass nodules (GGNs) are generally considered an early stage of lung cancer. The imaging characteristics and curative efficacy of multiple GGNs as…”
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3
Characterization of Histone Deacetylase Mechanisms in Cancer Development
Published in Frontiers in oncology (29-07-2021)“…Over decades of studies, accumulating evidence has suggested that epigenetic dysregulation is a hallmark of tumours. Post-translational modifications of…”
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Efficient and Regioselective One-Pot Synthesis of 3-Substituted and 3,5-Disubstituted Isoxazoles
Published in Organic letters (03-09-2009)“…A series of 3-substituted and 3,5-disubstituted isoxazoles have been efficiently synthesized in moderate to excellent yields by the reaction of…”
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Efficient and Regioselective Synthesis of 5-Hydroxy-2-isoxazolines: Versatile Synthons for Isoxazoles, β-Lactams, and γ-Amino Alcohols
Published in Journal of organic chemistry (19-03-2010)“…An efficient and highly regioselective protocol was developed for the preparation of 5-hydroxy-2-isoxazolines, which have been proved to be versatile synthons…”
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Proteomic and metabolomic profiling of plasma predicts immune-related adverse events in older patients with advanced non-small cell lung cancer
Published in iScience (21-06-2024)“…The clinical success of immune checkpoint inhibitors is compromised by the fact of immune-related adverse events (irAEs), especially for older patients. To…”
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Metastasis ability, genomic profile, subtype characteristic and curative efficacy of multiple pulmonary hematogenous metastases in lung cancer
Published in Clinical and translational medicine (01-03-2024)“…The CROWN study (N = 76) found that loratinib improved the intracranial objective response rate (iORR) (64.9% vs. 17.9%, p < 0.001) compared to clotozantinib…”
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Concise Total Syntheses of (+)-Strictifolione and (6R)-6-[(4R,6R)-4,6-Dihydroxy-10-phenyldec-1-enyl]-5,6-dihydro-2H-pyran-2-one
Published in Journal of organic chemistry (03-12-2010)“…Concise and efficient asymmetric total syntheses of (+)-strictifolione 1 and (6R)-6-[(4R,6R)-4,6-dihydroxy-10-phenyldec-1-enyl]-5,6-dihydro-2H-pyran-2-one 2…”
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Ground-glass opacity showed response to immunotherapy in cancer patients
Published in Journal of clinical oncology (01-06-2022)“…e14605 Background: Ground glass opacities (GGO) are lesions with hazy density on CT. Immune checkpoint inhibitors (ICIs) achieved a significant improvement in…”
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A newly defined risk signature, consisting of three m6A RNA methylation regulators, predicts the prognosis of ovarian cancer
Published in Aging (Albany, NY.) (20-09-2020)“…N6-methyladenosine (m 6 A) RNA methylation, involved in cancer initiation and progression, is dynamically regulated by the m 6 A RNA methylation regulators…”
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A newly defined risk signature, consisting of three m 6 A RNA methylation regulators, predicts the prognosis of ovarian cancer
Published in Aging (Albany, NY.) (20-09-2020)“…N6-methyladenosine (m A) RNA methylation, involved in cancer initiation and progression, is dynamically regulated by the m A RNA methylation regulators…”
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Concise Total Syntheses of (+)-Strictifolione and (6 R )-6-[(4 R ,6 R )-4,6-Dihydroxy-10-phenyldec-1-enyl]-5,6-dihydro-2 H -pyran-2-one
Published in Journal of organic chemistry (03-12-2010)Get full text
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13
Facile total synthesis of the antimalarial nonenolide
Published in Tetrahedron: asymmetry (01-05-2008)“…The facile total synthesis of the antimalarial nonenolide 1 is reported. The convergent strategy features the use of reactions such as Sharpless asymmetric…”
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