Search Results - "He, Kejun"
-
1
LinDA: linear models for differential abundance analysis of microbiome compositional data
Published in Genome Biology (14-04-2022)“…Differential abundance analysis is at the core of statistical analysis of microbiome data. The compositional nature of microbiome sequencing data makes false…”
Get full text
Journal Article -
2
A peptide encoded by circular form of LINC-PINT suppresses oncogenic transcriptional elongation in glioblastoma
Published in Nature communications (26-10-2018)“…Circular RNAs (circRNAs) are a large class of transcripts in the mammalian genome. Although the translation of circRNAs was reported, additional coding…”
Get full text
Journal Article -
3
Principal Component Analysis of Two-dimensional Functional Data with Serial Correlation
Published in Journal of agricultural, biological, and environmental statistics (01-09-2024)“…In this paper, we propose a novel model to analyze serially correlated two-dimensional functional data observed sparsely and irregularly on a domain which may…”
Get full text
Journal Article -
4
Circular EZH2-encoded EZH2-92aa mediates immune evasion in glioblastoma via inhibition of surface NKG2D ligands
Published in Nature communications (15-08-2022)“…Glioblastoma (GBM) is a highly aggressive primary brain tumour and is resistant to nearly all available treatments, including natural killer (NK) cell…”
Get full text
Journal Article -
5
Spline estimation of functional principal components via manifold conjugate gradient algorithm
Published in Statistics and computing (01-12-2022)“…Functional principal component analysis has become the most important dimension reduction technique in functional data analysis. Based on B-spline…”
Get full text
Journal Article -
6
Co-variability of the summer NDVIs on the eastern Tibetan Plateau and in the Lake Baikal region: Associated climate factors and atmospheric circulation
Published in PloS one (28-10-2020)“…The Tibetan Plateau and Siberia are both crucial regions in which the vegetation dynamics are sensitive to climate change. The variabilities in the normalized…”
Get full text
Journal Article -
7
The causal effects between selenium levels and the brain cortical structure: A two‐sample Mendelian randomization study
Published in Brain and behavior (01-12-2023)“…Extensive research has demonstrated the critical role of selenium (Se) and selenoproteins in brain function and cognition. However, the impact of Se on brain…”
Get full text
Journal Article -
8
A varying-coefficient regression approach to modeling the effects of wind speed on the dispersion of pollutants
Published in Environmental and ecological statistics (01-06-2022)“…The real-world monitoring system of air pollution ordinarily collects data about pollutant concentration levels at pollution sources and monitors stations in a…”
Get full text
Journal Article -
9
A tripole pattern of summer surface air temperature anomalies over northern Eurasia and its precursory signals in the tropical Atlantic and northern Asian land
Published in International journal of climatology (01-05-2021)“…This study investigates the variability of summer surface air temperature (SAT) over northern Eurasia and its precursory signals in the tropical Atlantic and…”
Get full text
Journal Article -
10
Precursory Signals (SST and Soil Moisture) of Summer Surface Temperature Anomalies over the Tibetan Plateau
Published in Atmosphere (01-01-2021)“…Understanding the variability of surface air temperature (SAT) over the Tibetan Plateau (TP) and its precursory signals is of great benefit to climate change…”
Get full text
Journal Article -
11
Aggrephagy-related gene signature correlates with survival and tumor-associated macrophages in glioma: Insights from single-cell and bulk RNA sequencing
Published in Mathematical biosciences and engineering : MBE (2024)“…Aggrephagy is a lysosome-dependent process that degrades misfolded protein condensates to maintain cancer cell homeostasis. Despite its importance in cellular…”
Get full text
Journal Article -
12
The gut microbiota and metabolite profiles are altered in patients with spinal cord injury
Published in Molecular brain (20-02-2023)“…Metabolites secreted by the gut microbiota may play an essential role in microbiota-gut-central nervous system crosstalk. In this study, we explored the…”
Get full text
Journal Article -
13
Successfully treated with siltuximab and prednisone in a 7-year-old girl with DOCK8 -deficiency presenting as recurrent wart-like lesions: a case report
Published in Frontiers in immunology (09-07-2024)“…Dedicator of cytokinesis 8 (DOCK8) deficiency represents a primary immunodeficiency with a wide range of clinical symptoms, including recurrent infections,…”
Get full text
Journal Article -
14
A Unified Bayesian Framework for Bi-overlapping-Clustering Multi-omics Data via Sparse Matrix Factorization
Published in Statistics in biosciences (01-12-2023)“…The advances of modern sequencing techniques have generated an unprecedented amount of multi-omics data which provide great opportunities to quantitatively…”
Get full text
Journal Article -
15
Operative treatment of cystic prolactinomas: a retrospective study
Published in BMC endocrine disorders (04-05-2023)“…The optimal therapeutic approach for cystic prolactinomas remains unclear. This study aimed to evaluate the remission rates of prolactinoma patients after…”
Get full text
Journal Article -
16
Tensor Linear Regression: Degeneracy and Solution
Published in IEEE access (2021)“…Tensor regression is an important and useful tool for analyzing multidimensional array data. To deal with high dimensionality, CANDECOMP/PARAFAC (CP) low-rank…”
Get full text
Journal Article -
17
U–Pb and Hf isotopic study of detrital zircons from the meta-sedimentary rocks in central Jiangxi Province, South China: Implications for the Neoproterozoic tectonic evolution of South China Block
Published in Journal of Asian earth sciences (30-04-2011)“…► Zhoutan Group deposited in the Neoproterozoic rather than Mesoproterozoic. ► Sediments may be derived both from the Yangtze Block and the Cathaysia Block. ►…”
Get full text
Journal Article -
18
Assessing the Multivariate Relationship between the Human Infant Intestinal Exfoliated Cell Transcriptome (Exfoliome) and Microbiome in Response to Diet
Published in Microorganisms (Basel) (18-12-2020)“…Gut microbiota and the host exist in a mutualistic relationship, with the functional composition of the microbiota strongly influencing the health and…”
Get full text
Journal Article -
19
Challenges and opportunities for managing pediatric central nervous system tumors in China
Published in Pediatric investigation (01-09-2020)“…Central nervous system (CNS) tumors represent the most deadly cancer in pediatric age group. In China, thousands of children are diagnosed with CNS tumors…”
Get full text
Journal Article -
20
Powerful Spatial Multiple Testing via Borrowing Neighboring Information
Published in Statistica Sinica (2026)Get full text
Journal Article