Search Results - "He, Jiaye"
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Image quality guided smart rotation improves coverage in microscopy
Published in Nature communications (09-01-2020)“…Fluorescence microscopy is an essential tool for biological discoveries. There is a constant demand for better spatial resolution across a larger field of…”
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A versatile cortical pattern-forming circuit based on Rho, F-actin, Ect2, and RGA-3/4
Published in The Journal of cell biology (01-08-2022)“…Many cells can generate complementary traveling waves of actin filaments (F-actin) and cytoskeletal regulators. This phenomenon, termed cortical excitability,…”
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KLC4 shapes axon arbors during development and mediates adult behavior
Published in eLife (12-10-2022)“…Development of elaborate and polarized neuronal morphology requires precisely regulated transport of cellular cargos by motor proteins such as kinesin-1…”
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Spatial transcriptomics reveals antiparasitic targets associated with essential behaviors in the human parasite Brugia malayi
Published in PLoS pathogens (01-04-2022)“…Lymphatic filariasis (LF) is a chronic debilitating neglected tropical disease (NTD) caused by mosquito-transmitted nematodes that afflicts over 60 million…”
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Efficient simulation of non-stationary non-homogeneous wind field: Fusion of multi-dimensional interpolation and NUFFT
Published in Journal of wind engineering and industrial aerodynamics (01-05-2023)“…The stochastic wave approach is a new realization of the spectral representation method and has been widely used for the simulation of stationary…”
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Efficacy of Voriconazole against Aspergillus fumigatus Infection Depends on Host Immune Function
Published in Antimicrobial agents and chemotherapy (27-01-2020)“…Antifungal therapy can fail in a remarkable number of patients with invasive fungal disease, resulting in significant morbidity worldwide. A major contributor…”
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Fast physic-informed mixer architecture for color Lensfree holographic reconstruction
Published in Optics and lasers in engineering (01-02-2024)“…•To improve reconstruction quality, we proposed an efficient complex-valued attention mixer (ECA-Mixer) architecture for fast and accurate physic-informed…”
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Self-inspired learning for denoising live-cell super-resolution microscopy
Published in Nature methods (01-10-2024)“…Every collected photon is precious in live-cell super-resolution (SR) microscopy. Here, we describe a data-efficient, deep learning-based denoising solution to…”
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Regenerative failure of intrahepatic biliary cells in Alagille syndrome rescued by elevated Jagged/Notch/Sox9 signaling
Published in Proceedings of the National Academy of Sciences - PNAS (13-12-2022)“…Despite the robust healing capacity of the liver, regenerative failure underlies numerous hepatic diseases, including the haploinsufficient disorder, Alagille…”
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Intrahepatic cholangiocyte regeneration from an Fgf‐dependent extrahepatic progenitor niche in a zebrafish model of Alagille Syndrome
Published in Hepatology (Baltimore, Md.) (01-03-2022)“…Background and Aims Alagille Syndrome (ALGS) is a congenital disorder caused by mutations in the Notch ligand gene JAGGED1, leading to neonatal loss of…”
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Label-free redox imaging of patient-derived organoids using selective plane illumination microscopy
Published in Biomedical optics express (01-05-2020)“…High-throughput drug screening of patient-derived organoids offers an attractive platform to determine cancer treatment efficacy. Here, selective plane…”
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