Search Results - "He, Jiaxue"
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HPV genotypic spectrum in Jilin province, China, where non-vaccine-covered HPV53 and 51 are prevalent, exhibits a bimodal age-specific pattern
Published in PloS one (24-03-2020)“…Human papillomavirus (HPV), the most common sexually transmitted disease, is involved in a series of other diseases. The persistent infection of high-risk HPVs…”
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Characteristics of Genomic Alterations in Pericardial Effusion of Advanced Non-small Cell Lung Cancer
Published in Frontiers in genetics (12-05-2022)“…The feasibility and value of pericardial effusion as a liquid biopsy sample for actionable alteration detection in patients with non-small cell lung cancer…”
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Combining Genetic Mutation and Expression Profiles Identifies Novel Prognostic Biomarkers of Lung Adenocarcinoma
Published in Clinical Medicine Insights. Oncology (2020)“…Motivation: Although several prognostic signatures for lung adenocarcinoma (LUAD) have been developed, they are mainly based on a single-omics data set. This…”
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Nicotinamide phosphoribosyltransferase (Nampt) affects the lineage fate determination of mesenchymal stem cells: A possible cause for reduced osteogenesis and increased adipogenesis in older individuals
Published in Journal of bone and mineral research (01-11-2011)“…Human aging is associated with a progressive decline in bone mass and an accumulation of marrow fat. We found that osteoblast differentiation was reduced and…”
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VFM: Identification of Bacteriophages From Metagenomic Bins and Contigs Based on Features Related to Gene and Genome Composition
Published in IEEE access (2019)“…As the main regulator of microbial community composition, bacteriophages exist widely on Earth. However, since they are hidden in metagenomes, most of them are…”
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Double-layer focal plane microscopy for high throughput DNA sequencing
Published in Optics express (23-05-2022)“…Throughput is one of the most important properties in DNA sequencing. We propose a novel double-layer focal plane microscopy that doubles the DNA sequencing…”
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Molecular profiles of different PD-L1 expression in patients with esophageal squamous cell carcinoma
Published in Cancer biology & therapy (31-12-2023)“…PD-1/PD-L1 inhibitors are approved treatments for patients with esophageal squamous cell carcinoma (ESCC). The present investigation aspired to explore the…”
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Digital PCR is a sensitive new technique for SARS-CoV-2 detection in clinical applications
Published in Clinica chimica acta (01-12-2020)“…•Digital PCR is a sensitive new technique for SARS-CoV-2 detection in clinical applications.•Digital PCR would substantially reduce the rates of false-negative…”
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Virsearcher: Identifying Bacteriophages from Metagenomes by Combining Convolutional Neural Network and Gene Information
Published in IEEE/ACM transactions on computational biology and bioinformatics (01-01-2023)“…Metagenome sequencing provides an unprecedented opportunity for the discovery of unknown microbes and viruses. A large number of phages and prokaryotes are…”
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Increased CD4+CXCR5+T follicular helper cells in diabetic nephropathy
Published in Autoimmunity (Chur, Switzerland) (01-09-2016)“…Background: T follicular helper (Tfh) cells are known to regulate humoral immune response. In this study we examined the correlation of different subsets of…”
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Nicotinamide phosphoribosyltransferase (Nampt) may serve as the marker for osteoblast differentiation of bone marrow-derived mesenchymal stem cells
Published in Experimental cell research (01-03-2017)“…Decreased bone volume and strength with aging and enhanced risk of fractures are in part due to reduced number of bone-forming mesenchymal stem cells (MSCs)…”
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Nampt expression increases during osteogenic differentiation of multi- and omnipotent progenitors
Published in Biochemical and biophysical research communications (26-04-2013)“…•Nampt was increasingly expressed during differentiation of osteoblast progenitors.•NAD concentration and Sirt1 activity increased with osteoblast…”
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TCP10L negatively regulates alpha-fetoprotein expression in hepatocellular carcinoma
Published in BMB reports (31-08-2020)“…Alpha-fetoprotein (AFP) is one of the most commonly used and reliable biomarkers for Hepatocellular carcinoma(HCC). However, the underlying mechanism of AFP…”
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TCP10L synergizes with MAD1 in transcriptional suppression and cell cycle arrest through mutual interaction
Published in BMB reports (30-06-2016)“…T-complex protein 10A homolog 2 (TCP10L) was previously demonstrated to be a potential tumor suppressor in human hepatocellular carcinoma (HCC). However,…”
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Aurora-A kinase-inactive mutants disrupt the interaction with Ajuba and cause defects in mitotic spindle formation and G2/M phase arrest in HeLa cells
Published in BMB reports (2014)“…Aurora-A is a centrosome-localized serine/threonine kinase that is overexpressed in multiple human cancers. We previously reported an intramolecular inhibitory…”
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