Search Results - "He, Huiling"

Genetic Predisposition to Papillary Thyroid Carcinoma: Involvement of FOXE1, TSHR, and a Novel lincRNA Gene, PTCSC2 by He, Huiling, Li, Wei, Liyanarachchi, Sandya, Jendrzejewski, Jaroslaw, Srinivas, Mukund, Davuluri, Ramana V, Nagy, Rebecca, de la Chapelle, Albert

“…Context: By genome-wide association studies, the risk allele [A] of SNP rs965513 predisposes strongly to papillary thyroid carcinoma (PTC). It is located in a…”
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polymorphism rs944289 predisposes to papillary thyroid carcinoma through a large intergenic noncoding RNA gene of tumor suppressor type by Jendrzejewski, Jaroslaw, He, Huiling, Radomska, Hanna S, Li, Wei, Tomsic, Jerneja, Liyanarachchi, Sandya, Davuluri, Ramana V, Nagy, Rebecca, de la Chapelle, Albert

“…A genome-wide association study of papillary thyroid carcinoma (PTC) pinpointed two independent SNPs (rs944289 and rs965513) located in regions containing no…”
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HABP2 G534E Variant in Papillary Thyroid Carcinoma by Tomsic, Jerneja, Fultz, Rebecca, Liyanarachchi, Sandya, He, Huiling, Senter, Leigha, de la Chapelle, Albert

“…The main nonmedullary form of thyroid cancer is papillary thyroid carcinoma (PTC) that accounts for 80-90% of all thyroid malignancies. Only 3-10% of PTC…”
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A germline mutation in SRRM2, a splicing factor gene, is implicated in papillary thyroid carcinoma predisposition by Tomsic, Jerneja, He, Huiling, Akagi, Keiko, Liyanarachchi, Sandya, Pan, Qun, Bertani, Blake, Nagy, Rebecca, Symer, David E., Blencowe, Benjamin J., Chapelle, Albert de la

“…Papillary thyroid carcinoma (PTC) displays strong but so far largely uncharacterized heritability. Here we studied genetic predisposition in a family with six…”
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Assessing thyroid cancer risk using polygenic risk scores by Liyanarachchi, Sandya, Gudmundsson, Julius, Ferkingstad, Egil, He, Huiling, Jonasson, Jon G., Tragante, Vinicius, Asselbergs, Folkert W., Xu, Li, Kiemeney, Lambertus A., Netea-Maier, Romana T., Mayordomo, Jose I., Plantinga, Theo S., Hjartarson, Hannes, Hrafnkelsson, Jon, Sturgis, Erich M., Brock, Pamela, Nabhan, Fadi, Thorleifsson, Gudmar, Ringel, Matthew D., Stefansson, Kari, de la Chapelle, Albert

“…Genome-wide association studies (GWASs) have identified at least 10 single-nucleotide polymorphisms (SNPs) associated with papillary thyroid cancer (PTC) risk…”
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Combined analysis of single-cell and bulk RNA sequencing reveals the expression patterns of circadian rhythm disruption in the immune microenvironment of Alzheimer's disease by He, Huiling, Yang, Yingxia, Wang, Lingxing, Guo, Zeming, Ye, Lichao, Ou-Yang, Wanjiong, Yang, Meili

“…Circadian rhythm disruption (CRD) represents a critical contributor to the pathogenesis of Alzheimer's disease (AD). Nonetheless, how CRD functions within the…”
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Mutations in U4atac snRNA, a Component of the Minor Spliceosome, in the Developmental Disorder MOPD I by He, Huiling, Liyanarachchi, Sandya, Akagi, Keiko, Nagy, Rebecca, Li, Jingfeng, Dietrich, Rosemary C., Li, Wei, Sebastian, Nikhil, Wen, Bernard, Xin, Baozhong, Singh, Jarnail, Yan, Pearlly, Alder, Hansjuerg, Haan, Eric, Wieczorek, Dagmar, Albrecht, Beate, Puffenberger, Erik, Wang, Heng, Westman, Judith A., Padgett, Richard A., Symer, David E., de la Chapelle, Albert

“…Small nuclear RNAs (snRNAs) are essential factors in messenger RNA splicing. By means of homozygosity mapping and deep sequencing, we show that a gene encoding…”
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Multiple functional variants in long-range enhancer elements contribute to the risk of SNP rs965513 in thyroid cancer by He, Huiling, Li, Wei, Liyanarachchi, Sandya, Srinivas, Mukund, Wang, Yanqiang, Akagi, Keiko, Wang, Yao, Wu, Dayong, Wang, Qianben, Jin, Victor, Symer, David E., Shen, Rulong, Phay, John, Nagy, Rebecca, de la Chapelle, Albert

“…Significance Papillary thyroid carcinoma (PTC) displays a strong hereditary component that is, in part, due to the additive effects of numerous low-penetrance…”
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The Role of MicroRNA Genes in Papillary Thyroid Carcinoma by He, Huiling, Krystian Jazdzewski, Li, Wei, Liyanarachchi, Sandya, Rebecca Nagy, Volinia, Stefano, Calin, George A., Liu, Chang-gong, Kaarle Franssila, Suster, Saul, Kloos, Richard T., Croce, Carlo M., de la Chapelle, Albert

“…Apart from alterations in the RET/PTC-RAS-BRAF pathway, comparatively little is known about the genetics of papillary thyroid carcinoma (PTC). We show that…”
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The Role of NRG1 in the Predisposition to Papillary Thyroid Carcinoma by He, Huiling, Li, Wei, Liyanarachchi, Sandya, Wang, Yanqiang, Yu, Lianbo, Genutis, Luke K, Maharry, Sophia, Phay, John E, Shen, Rulong, Brock, Pamela, de la Chapelle, Albert

“…Abstract Context Previous genome-wide association studies have shown that single-nucleotide polymorphism (SNP) rs2439302 in chromosome 8p12 is significantly…”
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Transcriptome analysis discloses dysregulated genes in normal appearing tumor-adjacent thyroid tissues from patients with papillary thyroid carcinoma by He, Huiling, Liyanarachchi, Sandya, Li, Wei, Comiskey, Daniel F., Yan, Pearlly, Bundschuh, Ralf, Turkoglu, Altan M., Brock, Pamela, Ringel, Matthew D., de la Chapelle, Albert

“…Papillary thyroid carcinoma (PTC) is the most common type of thyroid cancer. The molecular characteristics of histologically normal appearing tissue adjacent…”
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Gene expression and functional evidence of epithelial-to-mesenchymal transition in papillary thyroid carcinoma invasion by Vasko, Vasily, Espinosa, Allan V, Scouten, William, He, Huiling, Auer, Herbert, Liyanarachchi, Sandya, Larin, Alexander, Savchenko, Victoria, Francis, Gary L, de la Chapelle, Albert, Saji, Motoyasu, Ringel, Matthew D

“…Papillary thyroid carcinomas (PTCs) that invade into local structures are associated with a poor prognosis, but the mechanisms for PTC invasion are…”
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Papillary Thyroid Carcinoma: Association Between Germline DNA Variant Markers and Clinical Parameters by Jendrzejewski, Jaroslaw, Liyanarachchi, Sandya, Nagy, Rebecca, Senter, Leigha, Wakely, Paul E, Thomas, Andrew, Nabhan, Fadi, He, Huiling, Li, Wei, Sworczak, Krzysztof, Ringel, Matthew D, Kirschner, Lawrence S, de la Chapelle, Albert

“…Papillary thyroid cancer (PTC) is reported to be highly heritable in epidemiological studies. Genome-wide association studies (GWAS) have uncovered several…”
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A Susceptibility Locus for Papillary Thyroid Carcinoma on Chromosome 8q24 by HUILING HE, NAGY, Rebecca, LIYANARACHCHI, Sandya, HONG JIAO, WEI LI, SUSTER, Saul, KERE, Juha, DE LA CHAPELLE, Albert

“…Papillary thyroid carcinoma (PTC) displays higher heritability than most other cancers. To search for genes predisposing to PTC, we performed a genome-wide…”
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CpxA/R‐Controlled Nitroreductase Expression as Target for Combinatorial Therapy against Uropathogens by Promoting Reactive Oxygen Species Generation by Ren, Hao, Zhong, Zixing, Zhou, Shuang, Wei, Yiyang, Liang, Yujiao, He, Huiling, Zheng, Zijian, Li, Mengyuan, He, Qian, Long, Tengfei, Lian, Xinlei, Liao, Xiaoping, Liu, Yahong, Sun, Jian

“…The antibiotic resistances emerged in uropathogens lead to accumulative treatment failure and recurrent episodes of urinary tract infection (UTI),…”
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Identification of a novel noncoding RNA gene, NAMA, that is downregulated in papillary thyroid carcinoma with BRAF mutation and associated with growth arrest by Yoon, Heejei, He, Huiling, Nagy, Rebecca, Davuluri, Ramana, Suster, Saul, Schoenberg, Daniel, Pellegata, Natalia, Chapelle, Albert de la

“…In search of tumor suppressor genes in papillary thyroid carcinoma (PTC), we previously used gene expression profiling to identify genes underexpressed in…”
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The impact of chronic intermittent hypoxia on the expression of intercellular cell adhesion molecule-1 and vascular endothelial growth factor in the ischemia-reperfusion rat model by Yang, Meili, Chen, Yafang, Wu, Zhengang, Zhang, Yaping, Cai, Ruowei, Ye, Lichao, Huang, Yinhui, Wang, Lingxing, He, Huiling

“…The aim of this study was to investigate the effect and mechanism of chronic intermittent hypoxia (CIH) on cerebral injury using the ischemia-reperfusion rat…”
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Microarray Analysis Uncovers the Induction of the Proapoptotic BH3-only Protein Bim in Multiple Models of Glucocorticoid-induced Apoptosis by Wang, Zhengqi, Malone, Michael H, He, Huiling, McColl, Karen S, Distelhorst, Clark W

“…Despite being one of the earliest recognized and most clinically relevant forms of apoptosis, little is known about the transcriptional events that mediate…”
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A novel essential splice site variant in SPTB in a large hereditary spherocytosis family by Nieminen, Taina T., Liyanarachchi, Sandya, Comiskey, Daniel F., Wang, Yanqiang, Li, Wei, Hendrickson, Isabella V., Brock, Pamela, Chapelle, Albert, He, Huiling

“…Background We studied a large family with 22 individuals affected with autosomal dominant hereditary spherocytosis (HS). Methods Genome‐wide linkage,…”
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Role of PTPRJ genotype in papillary thyroid carcinoma risk by Iuliano, Rodolfo, Palmieri, Dario, He, Huiling, Iervolino, Angela, Borbone, Eleonora, Pallante, Pierlorenzo, Cianflone, Alessandra, Nagy, Rebecca, Alder, Hansjuerg, Calin, George A, Trapasso, Francesco, Giordano, Carla, Croce, Carlo M, de la Chapelle, Albert, Fusco, Alfredo

“…The strong genetic predisposition to papillary thyroid carcinoma (PTC) might be due to a combination of low-penetrance susceptibility variants. Thus, the…”
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