Search Results - "He, Hai Tao"
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Detecting nanodomains in living cell membrane by fluorescence correlation spectroscopy
Published in Annual review of physical chemistry (01-01-2011)“…Cell membranes actively participate in numerous cellular functions. Inasmuch as bioactivities of cell membranes are known to depend crucially on their lateral…”
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2
Dynamic molecular confinement in the plasma membrane by microdomains and the cytoskeleton meshwork
Published in The EMBO journal (26-07-2006)“…It is by now widely recognized that cell membranes show complex patterns of lateral organization. Two mechanisms involving either a lipid‐dependent…”
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3
Dynamics in the plasma membrane: how to combine fluidity and order
Published in The EMBO journal (09-08-2006)“…Cell membranes are fascinating supramolecular aggregates that not only form a barrier between compartments but also harbor many chemical reactions essential to…”
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4
Dysregulation of non-coding RNAs in gastric cancer
Published in World journal of gastroenterology : WJG (21-10-2015)“…Gastric cancer(GC) is one of the most common cancers in the world and a significant threat to the health of patients, especially those from China and Japan…”
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5
Palmitoylation is required for efficient Fas cell death signaling
Published in The EMBO journal (10-01-2007)“…Localization of the death receptor Fas to specialized membrane microdomains is crucial to Fas‐mediated cell death signaling. Here, we report that the…”
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6
Biomarker and competing endogenous RNA potential of tumor-specific long noncoding RNA in chromophobe renal cell carcinoma
Published in OncoTargets and therapy (01-01-2016)“…Accumulating evidence suggests long noncoding RNAs (lncRNAs) play important roles in the initiation and progression of cancers. However, their functions in…”
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Raft nanodomains contribute to Akt/PKB plasma membrane recruitment and activation
Published in Nature chemical biology (01-09-2008)“…Membrane rafts are thought to be sphingolipid- and cholesterol-dependent lateral assemblies involved in diverse cellular functions. Their biological roles and…”
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8
Phosphoinositides regulate the TCR/CD3 complex membrane dynamics and activation
Published in Scientific reports (21-03-2018)“…Phosphoinositides (PIs) play important roles in numerous membrane-based cellular activities. However, their involvement in the mechanism of T cell receptor…”
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T‐cell antigen receptor triggering and lipid rafts: a matter of space and time scales: Talking Point on the involvement of lipid rafts in T-cell activation
Published in EMBO reports (01-06-2008)“…T‐cell antigen receptor triggering mechanisms and lipid rafts are of broad interest, but are also controversial topics. Here, we review some recent progress in…”
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10
TCR and CD28 Concomitant Stimulation Elicits a Distinctive Calcium Response in Naive T Cells
Published in Frontiers in immunology (04-12-2018)“…T cell activation is initiated upon ligand engagement of the T cell receptor (TCR) and costimulatory receptors. The CD28 molecule acts as a major costimulatory…”
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An essential role for membrane rafts in the initiation of Fas/CD95-triggered cell death in mouse thymocytes
Published in EMBO reports (01-02-2002)“…Fas, a member of the tumor necrosis factor receptor family, can upon ligation by its ligand or agonistic antibodies trigger signaling cascades leading to cell…”
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12
TCR signal initiation machinery is pre-assembled and activated in a subset of membrane rafts
Published in The EMBO journal (15-04-2002)“…Recent studies suggest that rafts are involved in numerous cell functions, including membrane traffic and signaling. Here we demonstrate, using a…”
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13
Barcoding T cell calcium response diversity with methods for automated and accurate analysis of cell signals (MAAACS)
Published in PLoS computational biology (01-09-2013)“…We introduce a series of experimental procedures enabling sensitive calcium monitoring in T cell populations by confocal video-microscopy. Tracking and…”
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14
Probing the plasma membrane organization in living cells by spot variation fluorescence correlation spectroscopy
Published in Methods in enzymology (2013)“…While intrinsic Brownian agitation within a lipid bilayer does homogenize the molecular distribution, the extremely diverse composition of the plasma membrane,…”
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15
Engagement of T cell receptor triggers its recruitment to low-density detergent-insoluble membrane domains
Published in The EMBO journal (15-09-1998)“…T‐cell receptors (TCRs) upon binding to peptide–MHC ligands transduce signals in T lymphocytes. Tyrosine phosphorylations in the cytoplasmic domains of the CD3…”
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16
Membrane rafts and signaling by the multichain immune recognition receptors
Published in Current Opinion in Immunology (01-06-2000)“…The recent recognition of the presence of rafts in the plasma membrane and of their involvement in cell signaling has strongly stimulated the search for their…”
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Siah1 proteins enhance radiosensitivity of human breast cancer cells
Published in BMC cancer (03-08-2010)“…Siah proteins play an important role in cancer progression. We evaluated the effect of Siah1, its splice variants Siah1L and the Siah1 mutant with the RING…”
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Characterization of Brucella abortus lipopolysaccharide macrodomains as mega rafts
Published in Cellular microbiology (01-02-2006)“…Summary The lipopolysaccharides (LPS) of intracellular Proteobacteria such as Brucella, Chlamydia, Legionella and Rickettsia, have properties distinct from…”
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Glycosylation-Dependent IFN-γR Partitioning in Lipid and Actin Nanodomains Is Critical for JAK Activation
Published in Cell (11-08-2016)“…Understanding how membrane nanoscale organization controls transmembrane receptors signaling activity remains a challenge. We studied interferon-γ receptor…”
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Coronin‐1 expression in T lymphocytes: insights into protein function during T cell development and activation
Published in International immunology (01-02-2004)“…Coronin has been described as an actin‐binding protein of Dictyostelium discoideum, and it has been demonstrated to play a role in cell migration, cytokinesis…”
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