Search Results - "Hazle, John D."
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The Skp2-SCF E3 Ligase Regulates Akt Ubiquitination, Glycolysis, Herceptin Sensitivity, and Tumorigenesis
Published in Cell (25-05-2012)“…Akt kinase plays a central role in cell growth, metabolism, and tumorigenesis. The TRAF6 E3 ligase orchestrates IGF-1-mediated Akt ubiquitination and…”
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A Machine-Learning Algorithm Toward Color Analysis for Chronic Liver Disease Classification, Employing Ultrasound Shear Wave Elastography
Published in Ultrasound in medicine & biology (01-09-2017)“…Abstract The purpose of the present study was to employ a computer-aided diagnosis system that classifies chronic liver disease (CLD) using ultrasound shear…”
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Temporal stability assessment in shear wave elasticity images validated by deep learning neural network for chronic liver disease fibrosis stage assessment
Published in Medical physics (Lancaster) (01-05-2019)“…Purpose To automatically detect and isolate areas of low and high stiffness temporal stability in shear wave elastography (SWE) image sequences and define…”
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Robust phase unwrapping for MR temperature imaging using a magnitude-sorted list, multi-clustering algorithm
Published in Magnetic resonance in medicine (01-04-2015)“…Purpose Several methods in MRI use the phase information of the complex signal and require phase unwrapping (e.g., B0 field mapping, chemical shift imaging,…”
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A machine learning model to predict hepatocellular carcinoma response to transcatheter arterial chemoembolization
Published in Radiology. Artificial intelligence (01-09-2019)“…Some patients with hepatocellular carcinoma (HCC) are more likely to experience disease progression despite transcatheter arterial chemoembolization (TACE)…”
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Intravoxel incoherent motion imaging kinetics during chemoradiotherapy for human papillomavirus-associated squamous cell carcinoma of the oropharynx: preliminary results from a prospective pilot study
Published in NMR in biomedicine (01-12-2015)“…This study aims to identify the temporal kinetics of intravoxel incoherent motion (IVIM) MRI in patients with human papillomavirus‐associated (HPV+)…”
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Feasibility of Automated Volumetric Assessment of Large Hepatocellular Carcinomas' Responses to Transarterial Chemoembolization
Published in Frontiers in oncology (07-05-2020)“…Hepatocellular carcinoma (HCC) is the most common liver malignancy and the leading cause of death in patients with cirrhosis. Various treatments for HCC are…”
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Past AAPM President: 2013
Published in Medical physics (Lancaster) (01-06-2023)Get full text
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Multimodality annotated hepatocellular carcinoma data set including pre- and post-TACE with imaging segmentation
Published in Scientific data (18-01-2023)“…Hepatocellular carcinoma (HCC) is the most common primary liver neoplasm, and its incidence has doubled over the past two decades owing to increasing risk…”
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10
The Skp2-SCF E3 Ligase Regulates Akt Ubiquitination, Glycolysis, Herceptin Sensitivity, and Tumorigenesis
Published in Cell (09-11-2012)Get full text
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11
Magnetic resonance imaging of swallowing-related structures in nasopharyngeal carcinoma patients receiving IMRT: Longitudinal dose–response characterization of quantitative signal kinetics
Published in Radiotherapy and oncology (01-02-2016)“…Abstract Background We aim to characterize serial (i.e., acute and late) MRI signal intensity (SI) changes in dysphagia-associated structures as a function of…”
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Technical Note: A Monte Carlo study of magnetic‐field‐induced radiation dose effects in mice
Published in Medical physics (Lancaster) (01-09-2015)“…Purpose: Magnetic fields are known to alter radiation dose deposition. Before patients receive treatment using an MRI‐linear accelerator (MRI‐Linac),…”
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13
MR temperature imaging of nanoshell mediated laser ablation
Published in International journal of hyperthermia (01-12-2011)“…Minimally invasive thermal therapy using high-power diode lasers is an active area of clinical research. Gold nanoshells (AuNS) can be tuned to absorb light in…”
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14
MR thermometry-based feedback control of laser interstitial thermal therapy at 980 nm
Published in Lasers in surgery and medicine (01-01-2004)“…Background and Objectives The goal of this study was to explore the feasibility of magnetic resonance thermal imaging (MRTI)‐based feedback control of…”
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IClinfMRI Software for Integrating Functional MRI Techniques in Presurgical Mapping and Clinical Studies
Published in Frontiers in neuroinformatics (09-03-2018)“…Task-evoked and resting-state (rs) functional magnetic resonance imaging (fMRI) techniques have been applied to the clinical management of neurological…”
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Laser-induced thermal response and characterization of nanoparticles for cancer treatment using magnetic resonance thermal imaging
Published in Medical physics (Lancaster) (01-07-2007)“…Spherical nanoparticles with a gold outer shell and silica core can be tuned to absorb near-infrared light of a specific wavelength. These nanoparticles have…”
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Fat-suppressed three-dimensional dual echo dixon technique for contrast agent enhanced MRI
Published in Journal of magnetic resonance imaging (01-01-2006)“…Purpose To develop a fast T1‐weighted, fat‐suppressed three‐dimensional dual echo Dixon technique and to demonstrate its use in contrast agent enhanced MRI…”
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Artificial intelligence-assisted mapping of proliferation centers allows the distinction of accelerated phase from large cell transformation in chronic lymphocytic leukemia
Published in Modern pathology (01-08-2022)“…Chronic lymphocytic leukemia/small lymphocytic lymphoma (CLL) is characterized morphologically by numerous small lymphocytes and pale nodules composed of…”
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Focal liver lesions segmentation and classification in nonenhanced T2‐weighted MRI
Published in Medical physics (Lancaster) (01-07-2017)“…Purpose To automatically segment and classify focal liver lesions (FLLs) on nonenhanced T2‐weighted magnetic resonance imaging (MRI) scans using a…”
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Deep learning networks on chronic liver disease assessment with fine-tuning of shear wave elastography image sequences
Published in Physics in medicine & biology (05-11-2020)“…Chronic liver disease (CLD) is currently one of the major causes of death worldwide. If not treated, it may lead to cirrhosis, hepatic carcinoma and death…”
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