Search Results - "Hazle, John"
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Past AAPM President: 2013
Published in Medical physics (Lancaster) (01-06-2023)Get full text
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The Skp2-SCF E3 Ligase Regulates Akt Ubiquitination, Glycolysis, Herceptin Sensitivity, and Tumorigenesis
Published in Cell (25-05-2012)“…Akt kinase plays a central role in cell growth, metabolism, and tumorigenesis. The TRAF6 E3 ligase orchestrates IGF-1-mediated Akt ubiquitination and…”
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Copper Sulfide Nanoparticles As a New Class of Photoacoustic Contrast Agent for Deep Tissue Imaging at 1064 nm
Published in ACS nano (28-08-2012)“…Photoacoustic tomography (PAT) is an emerging molecular imaging modality. Here, we demonstrate use of semiconductor copper sulfide nanoparticles (CuS NPs) for…”
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A radiomic‐ and dosiomic‐based machine learning regression model for pretreatment planning in 177 Lu‐DOTATATE therapy
Published in Medical physics (Lancaster) (01-11-2023)“…BACKGROUNDStandardized patient-specific pretreatment dosimetry planning is mandatory in the modern era of nuclear molecular radiotherapy, which may eventually…”
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A Machine-Learning Algorithm Toward Color Analysis for Chronic Liver Disease Classification, Employing Ultrasound Shear Wave Elastography
Published in Ultrasound in medicine & biology (01-09-2017)“…Abstract The purpose of the present study was to employ a computer-aided diagnosis system that classifies chronic liver disease (CLD) using ultrasound shear…”
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Temporal stability assessment in shear wave elasticity images validated by deep learning neural network for chronic liver disease fibrosis stage assessment
Published in Medical physics (Lancaster) (01-05-2019)“…Purpose To automatically detect and isolate areas of low and high stiffness temporal stability in shear wave elastography (SWE) image sequences and define…”
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Artificial intelligence-assisted mapping of proliferation centers allows the distinction of accelerated phase from large cell transformation in chronic lymphocytic leukemia
Published in Modern pathology (01-08-2022)“…Chronic lymphocytic leukemia/small lymphocytic lymphoma (CLL) is characterized morphologically by numerous small lymphocytes and pale nodules composed of…”
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Focal liver lesions segmentation and classification in nonenhanced T2‐weighted MRI
Published in Medical physics (Lancaster) (01-07-2017)“…Purpose To automatically segment and classify focal liver lesions (FLLs) on nonenhanced T2‐weighted magnetic resonance imaging (MRI) scans using a…”
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Deep learning networks on chronic liver disease assessment with fine-tuning of shear wave elastography image sequences
Published in Physics in medicine & biology (05-11-2020)“…Chronic liver disease (CLD) is currently one of the major causes of death worldwide. If not treated, it may lead to cirrhosis, hepatic carcinoma and death…”
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An improved region growing algorithm for phase correction in MRI
Published in Magnetic resonance in medicine (01-08-2016)“…Purpose To develop an improved region‐growing algorithm for phase correction in MRI. Methods Phase correction in MRI can sometimes be formulated as selecting a…”
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Robust phase unwrapping for MR temperature imaging using a magnitude-sorted list, multi-clustering algorithm
Published in Magnetic resonance in medicine (01-04-2015)“…Purpose Several methods in MRI use the phase information of the complex signal and require phase unwrapping (e.g., B0 field mapping, chemical shift imaging,…”
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A machine learning model to predict hepatocellular carcinoma response to transcatheter arterial chemoembolization
Published in Radiology. Artificial intelligence (01-09-2019)“…Some patients with hepatocellular carcinoma (HCC) are more likely to experience disease progression despite transcatheter arterial chemoembolization (TACE)…”
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A new automated quantification algorithm for the detection and evaluation of focal liver lesions with contrast‐enhanced ultrasound
Published in Medical physics (Lancaster) (01-07-2015)“…Purpose: Detect and classify focal liver lesions (FLLs) from contrast‐enhanced ultrasound (CEUS) imaging by means of an automated quantification algorithm…”
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Machine learning-based texture analysis for differentiation of radiologically indeterminate small adrenal tumors on adrenal protocol CT scans
Published in Abdominal radiology (New York) (01-10-2021)“…Goal To evaluate the ability of radiomic feature extraction and a machine learning algorithm to differentiate between benign and malignant indeterminate…”
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Theoretical model for laser ablation outcome predictions in brain: calibration and validation on clinical MR thermometry images
Published in International journal of hyperthermia (01-02-2018)“…Neurosurgical laser ablation is experiencing a renaissance. Computational tools for ablation planning aim to further improve the intervention. Here, global…”
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One-Pot, One-Step Synthesis of Drug-Loaded Magnetic Multimicelle Aggregates
Published in Bioconjugate chemistry (18-05-2022)“…Lipid-based formulations provide a nanotechnology platform that is widely used in a variety of biomedical applications because it has several advantageous…”
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A model combining pretreatment MRI radiomic features and tumor-infiltrating lymphocytes to predict response to neoadjuvant systemic therapy in triple-negative breast cancer
Published in European journal of radiology (01-04-2022)“…•Pretreatment MRI radiomic features can predict treatment response in breast cancer.•Combined MRI radiomic and TIL model improves accuracy of response…”
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Guiding the first biopsy in glioma patients using estimated Ki-67 maps derived from MRI: conventional versus advanced imaging
Published in Neuro-oncology (Charlottesville, Va.) (18-03-2019)“…Abstract Background Undersampling of gliomas at first biopsy is a major clinical problem, as accurate grading determines all subsequent treatment. We submit a…”
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Role of Wnt/β-catenin signaling in hepatocellular carcinoma, pathogenesis, and clinical significance
Published in Journal of hepatocellular carcinoma (01-01-2018)“…Hepatocellular carcinoma (HCC) is one of the most common primary hepatic malignancies and one of the fastest-growing causes of cancer-related mortality in the…”
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Institutional Strategies to Maintain and Grow Imaging Research During the COVID-19 Pandemic
Published in Academic radiology (01-04-2023)“…Understanding imaging research experiences, challenges, and strategies for academic radiology departments during and after COVID-19 is critical to prepare for…”
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