Search Results - "Hazin, John"

Identification of artesunate as a specific activator of ferroptosis in pancreatic cancer cells by Eling, Nils, Reuter, Lukas, Hazin, John, Hamacher-Brady, Anne, Brady, Nathan R

“…Oncogenic KRas reprograms pancreatic ductal adenocarcinoma (PDAC) cells to states which are highly resistant to apoptosis. Thus, a major preclinical goal is to…”
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L1CAM: A major driver for tumor cell invasion and motility by Kiefel, Helena, Bondong, Sandra, Hazin, John, Ridinger, Johannes, Schirmer, Uwe, Riedle, Svenja, Altevogt, Peter

“…The L1 cell adhesion molecule (L1CAM) plays a major role in the development of the nervous system and in the malignancy of human tumors. In terms of biological…”
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Full-length L1CAM and not its Δ2Δ27 splice variant promotes metastasis through induction of gelatinase expression by Hauser, Stephanie, Bickel, Laura, Weinspach, Dirk, Gerg, Michael, Schäfer, Michael K, Pfeifer, Marco, Hazin, John, Schelter, Florian, Weidle, Ulrich H, Ramser, Juliane, Volkmann, Juliane, Meindl, Alfons, Schmitt, Manfred, Schrötzlmair, Florian, Altevogt, Peter, Krüger, Achim

“…Tumour-specific splicing is known to contribute to cancer progression. In the case of the L1 cell adhesion molecule (L1CAM), which is expressed in many human…”
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Linking L1CAM-mediated signaling to NF-κB activation by Kiefel, Helena, Pfeifer, Marco, Bondong, Sandra, Hazin, John, Altevogt, Peter

“…The cell adhesion molecule L1 (L1CAM) was originally identified as a neural adhesion molecule essential for neurite outgrowth and axon guidance. Many studies…”
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A novel method for measuring cellular antibody uptake using imaging flow cytometry reveals distinct uptake rates for two different monoclonal antibodies targeting L1 by Hazin, John, Moldenhauer, Gerhard, Altevogt, Peter, Brady, Nathan R.

“…Monoclonal antibodies (mAbs) have emerged as a promising tool for cancer therapy. Differing approaches utilize mAbs to either deliver a drug to the tumor cells…”
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L1-mediated colon cancer cell metastasis does not require changes in EMT and cancer stem cell markers by Gavert, Nancy, Vivanti, Alessia, Hazin, John, Brabletz, Thomas, Ben-Ze'ev, Avri

“…Aberrant activation of Wnt/β-catenin signaling is common in most sporadic and inherited colorectal cancer (CRC) cells leading to elevated β-catenin/TCF…”
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Full-Length L1CAM and Not Its [DELTA]2[DELTA]27 Splice Variant Promotes Metastasis through Induction of Gelatinase Expression by Hauser, Stephanie, Bickel, Laura, Weinspach, Dirk, Gerg, Michael, Schäfer, Michael K, Pfeifer, Marco, Hazin, John, Schelter, Florian, Weidle, Ulrich H, Ramser, Juliane, Volkmann, Juliane, Meindl, Alfons, Schmitt, Manfred, Schrötzlmair, Florian, Altevogt, Peter, Krüger, Achim

“…Tumour-specific splicing is known to contribute to cancer progression. In the case of the L1 cell adhesion molecule (L1CAM), which is expressed in many human…”
Get full text