Search Results - "Hazewinkel, Herman A. W."

The Dog as an Animal Model for Intervertebral Disc Degeneration? by BERGKNUT, Niklas, RUTGES, Joost P. H. J, GRINWIS, Guy C. M, CREEMERS, Laura B, MEIJ, Björn P, DHERT, Wouter J. A, KRANENBURG, Hendrik-Jan C, SMOLDERS, Lucas A, HAGMAN, Ragnvi, SMIDT, Hendrik-Jan, LAGERSTEDT, Anne-Sofie, PENNING, Louis C, VOORHOUT, George, HAZEWINKEL, Herman A. W

“…Prospective observational and analytic study. To investigate whether spontaneous intervertebral disc degeneration (IVDD) occurring in both chondrodystrophic…”
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Genome wide analysis indicates genes for basement membrane and cartilage matrix proteins as candidates for hip dysplasia in Labrador Retrievers by Lavrijsen, Ineke C M, Leegwater, Peter A J, Martin, Alan J, Harris, Stephen J, Tryfonidou, Marianna A, Heuven, Henri C M, Hazewinkel, Herman A W

“…Hip dysplasia, an abnormal laxity of the hip joint, is seen in humans as well as dogs and is one of the most common skeletal disorders in dogs. Canine hip…”
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The effect of weight loss on lameness in obese dogs with osteoarthritis by Marshall, William G., Hazewinkel, Herman A. W., Mullen, Dermot, De Meyer, Geert, Baert, Katrien, Carmichael, Stuart

“…This paper describes the effect of weight loss on lameness in obese dogs with osteoarthritis (OA). Fourteen obese client-owned dogs with clinical and…”
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Pedicle Screw-Rod Fixation of the Canine Lumbosacral Junction by Smolders, Lucas A., Voorhout, George, van de Ven, Renée, Bergknut, Niklas, Grinwis, Guy C. M., Hazewinkel, Herman A. W., Meij, Björn P.

“…Objective To assess pedicle screw‐rod fixation (PSRF) of the canine lumbosacral junction (LSJ) ex vivo and in vivo. Study Design Ex vivo cadaver study and in…”
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Biomechanical assessment of the effects of decompressive surgery in non-chondrodystrophic and chondrodystrophic canine multisegmented lumbar spines by Smolders, Lucas A., Kingma, Idsart, Bergknut, Niklas, van der Veen, Albert J., Dhert, Wouter J. A., Hazewinkel, Herman A. W., van Dieën, Jaap H., Meij, Björn P.

“…Purpose Dogs are often used as an animal model in spinal research, but consideration should be given to the breed used as chondrodystrophic (CD) dog breeds…”
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Incidence of intervertebral disk degeneration-related diseases and associated mortality rates in dogs by Bergknut, Niklas, Egenvall, Agneta, Hagman, Ragnvi, Gustås, Pia, Hazewinkel, Herman A W, Meij, Björn P, Lagerstedt, Anne-Sofie

“…To determine the incidence and distribution of intervertebral disk (IVD) degeneration-related diseases in a large population of dogs of various breeds, ages,…”
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Evidence of Cartilage Repair by Joint Distraction in a Canine Model of Osteoarthritis by Wiegant, Karen, Intema, Femke, Roermund, Peter M., Barten‐van Rijbroek, Angelique D., Doornebal, Arie, Hazewinkel, Herman A. W., Lafeber, Floris P. J. G., Mastbergen, Simon C.

“…Objective Knee osteoarthritis (OA) is a degenerative joint disorder characterized by cartilage, bone, and synovial tissue changes that lead to pain and…”
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A differential effect of bone morphogenetic protein-2 and vascular endothelial growth factor release timing on osteogenesis at ectopic and orthotopic sites in a large-animal model by Geuze, Ruth E, Theyse, Lars F H, Kempen, Diederik H R, Hazewinkel, Herman A W, Kraak, Helen Y A, Oner, F Cumhur, Dhert, Wouter J A, Alblas, Jacqueline

“…In bone tissue engineering, growth factors are widely used. Bone morphogenetic proteins (BMPs) and vascular endothelial growth factor (VEGF) are the most…”
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Gene expression profiling of early intervertebral disc degeneration reveals a down-regulation of canonical Wnt signaling and caveolin-1 expression: implications for development of regenerative strategies by Smolders, Lucas A, Meij, Björn P, Onis, David, Riemers, Frank M, Bergknut, Niklas, Wubbolts, Richard, Grinwis, Guy C M, Houweling, Martin, Groot Koerkamp, Marian J A, van Leenen, Dik, Holstege, Frank C P, Hazewinkel, Herman A W, Creemers, Laura B, Penning, Louis C, Tryfonidou, Marianna A

“…Early degeneration of the intervertebral disc (IVD) involves a change in cellular differentiation from notochordal cells (NCs) in the nucleus pulposus (NP) to…”
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Radiographic, Computed Tomographic, and Arthroscopic Findings in Labrador Retrievers With Medial Coronoid Disease by Lau, Seng Fong, Theyse, Lars F.H., Voorhout, George, Hazewinkel, Herman A.W.

“…Objective To describe the radiographic, computed tomographic (CT), and arthroscopic findings in different age groups of Labrador Retrievers diagnosed with…”
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Fragmented coronoid process in the dog: A heritable disease by Temwichitr, Jedee, Leegwater, Peter A.J., Hazewinkel, Herman A.W.

“…Fragmented coronoid process (FCP) is one of the main diseases associated with elbow dysplasia. FCP is often diagnosed in medium-to-large breed dogs with front…”
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Biomechanical Flexion-Extension Forces in Normal Canine Lumbosacral Cadaver Specimens Before and After Dorsal Laminectomy-Discectomy and Pedicle Screw-Rod Fixation by MEIJ, BJÖRN P, SUWANKONG, NIYADA, VAN DER VEEN, ALBERT J, HAZEWINKEL, HERMAN A.W

“…To determine biomechanical flexion-extension forces in cadaveric canine lumbosacral specimens, before and after dorsal laminectomy with partial discectomy, and…”
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Design, synthesis, imaging, and biomechanics of a softness-gradient hydrogel nucleus pulposus prosthesis in a canine lumbar spine model by Kranenburg, Hendrik-Jan C., Meij, Björn P., Onis, David, van der Veen, Albert J., Saralidze, Ketie, Smolders, Luc A., Huizinga, Julie G., Knetsch, Menno L.W., Luijten, Peter R., Visser, Fredy, Voorhout, George, Dhert, Wouter J.A., Hazewinkel, Herman A.W., Koole, Leo H.

“…A hydrogel nucleus pulposus prosthesis (NPP) was designed to swell in situ, have intrinsic radiopacity, and restore intervertebral disc height and…”
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The performance of a hydrogel nucleus pulposus prosthesis in an ex vivo canine model by Bergknut, Niklas, Smolders, Lucas A, Koole, Leo H, Voorhout, George, Hagman, Ragnvi E, Lagerstedt, Anne-Sofie, Saralidze, Ketie, Hazewinkel, Herman A.W, van der Veen, Albert J, Meij, Björn P

“…Abstract A nucleus pulposus prosthesis (NPP) made of the hydrogel N-vinyl-2-pyrrolidinone copolymerized with 2-(4′-iodobenzoyl)-oxo-ethyl methacrylate has…”
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Intervertebral disc degeneration in the dog. Part 2: Chondrodystrophic and non-chondrodystrophic breeds by Smolders, Lucas A., Bergknut, Niklas, Grinwis, Guy C.M., Hagman, Ragnvi, Lagerstedt, Anne-Sofie, Hazewinkel, Herman A.W., Tryfonidou, Marianna A., Meij, Björn P.

“…Dogs can be grouped into two distinct types of breed based on the predisposition to chondrodystrophy, namely, non-chondrodystrophic (NCD) and chondrodystrophic…”
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Increased vitamin D-driven signalling and expression of the vitamin D receptor, MSX2, and RANKL in tooth resorption in cats by Booij-Vrieling, Henriëtte E., Ferbus, Didier, Tryfonidou, Marianna A., Riemers, Frank M., Penning, Louis C., Berdal, Ariane, Everts, Vincent, Hazewinkel, Herman A. W.

“…Booij‐Vrieling HE, Ferbus D, Tryfonidou MA, Riemers FM, Penning LC, Berdal A, Everts V, Hazewinkel HAW. Increased vitamin D‐driven signalling and expression of…”
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Intervertebral disc degeneration in the dog. Part 1: Anatomy and physiology of the intervertebral disc and characteristics of intervertebral disc degeneration by Bergknut, Niklas, Smolders, Lucas A., Grinwis, Guy C.M., Hagman, Ragnvi, Lagerstedt, Anne-Sofie, Hazewinkel, Herman A.W., Tryfonidou, Marianna A., Meij, Björn P.

“…Intervertebral disc (IVD) degeneration is common in dogs and can give rise to a number of diseases, such as IVD herniation, cervical spondylomyelopathy, and…”
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Evaluation of candidate genes as a cause of chondrodysplasia in Labrador retrievers by Smit, Jelke Jan, Temwitchitr, Jedee, Brocks, Bouvien A.W., Nikkels, Peter G.J., Hazewinkel, Herman A.W., Leegwater, Peter A.J.

“…Chondrodysplasia (CD) is a disabling, hereditary disease in Labradors with short limbs, warranting genetic screening in families at risk. Segregation analysis…”
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Evaluation of intervertebral disk degeneration in chondrodystrophic and nonchondrodystrophic dogs by use of Pfirrmann grading of images obtained with low-field magnetic resonance imaging by Bergknut, Niklas, Auriemma, Edoardo, Wijsman, Saffiera, Voorhout, George, Hagman, Ragnvi, Lagerstedt, Anne-Sofie, Hazewinkel, Herman A.W, Meij, Bjorn P

“…Objective—To assess whether the Pfirrmann system for grading lumbar intervertebral disk (IVD) degeneration in humans can also be used in dogs. Animals—202…”
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Intervertebral disc disease in dogs – Part 2: Comparison of clinical, magnetic resonance imaging, and histological findings in 74 surgically treated dogs by Kranenburg, Hendrik-Jan C., Grinwis, Guy C.M., Bergknut, Niklas, Gahrmann, Ninke, Voorhout, George, Hazewinkel, Herman A.W., Meij, Björn P.

“…The relationship between intervertebral disc (IVD) disease and IVD degeneration remains unclear. The aim of the present study was to compare the clinical…”
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