Search Results - "Hazenberg, Mette D."
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Human innate lymphoid cells
Published in Blood (31-07-2014)“…Innate lymphoid cells (ILCs) are lymphoid cells that do not express rearranged receptors and have important effector and regulatory functions in innate…”
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Interleukin-12 and -23 Control Plasticity of CD127+ Group 1 and Group 3 Innate Lymphoid Cells in the Intestinal Lamina Propria
Published in Immunity (Cambridge, Mass.) (21-07-2015)“…Human group 1 ILCs consist of at least three phenotypically distinct subsets, including NK cells, CD127+ ILC1, and intraepithelial CD103+ ILC1. In inflamed…”
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Cellular therapies for graft-versus-host disease: a tale of tissue repair and tolerance
Published in Blood (23-07-2020)“…The success of allogeneic hematopoietic cell transplantation depends heavily on the delicate balance between the activity of the donor immune system against…”
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Composition of Innate Lymphoid Cell Subsets in the Human Skin: Enrichment of NCR+ ILC3 in Lesional Skin and Blood of Psoriasis Patients
Published in Journal of investigative dermatology (01-09-2014)“…Innate lymphoid cells (ILCs) are increasingly appreciated as important regulators of tissue homeostasis and inflammation. However, their role in human skin…”
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Allogeneic hematopoietic cell transplantation, the microbiome, and graft-versus-host disease
Published in Gut microbes (31-12-2023)“…Many patients with hematological malignancies, such as acute myeloid leukemia, receive an allogeneic hematopoietic cell transplantation (HCT) to cure their…”
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The post-hematopoietic cell transplantation microbiome: relationships with transplant outcome and potential therapeutic targets
Published in Haematologica (Roma) (01-08-2021)“…Microbiota injury occurs in many patients undergoing allogeneic hematopoietic cell transplantation, likely as a consequence of conditioning regimens involving…”
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Mesenchymal Stromal Cells Stimulate the Proliferation and IL-22 Production of Group 3 Innate Lymphoid Cells
Published in The Journal of immunology (1950) (15-08-2018)“…Infusion of mesenchymal stromal cells (MSCs) is a promising and increasingly applied therapy for patients who suffer from a variety of inflammatory diseases,…”
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ATG versus PTCy in matched unrelated donor haematopoietic stem cell transplantations with non-myeloablative conditioning
Published in British journal of haematology (01-11-2023)“…Graft-versus-host disease (GvHD) is a serious complication of allogeneic haematopoietic stem cell transplantation (HSCT). Both anti-thymocyte globulin (ATG)…”
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Innate lymphoid cells are expanded and functionally altered in chronic lymphocytic leukemia
Published in Haematologica (Roma) (01-11-2016)Get full text
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Allogeneic hematopoietic cell transplantation in the management of GATA2 deficiency and pulmonary alveolar proteinosis
Published in Clinical immunology (Orlando, Fla.) (01-09-2020)“…Human hematopoiesis is critically dependent on the transcription factor GATA2. Patients with GATA2 deficiency typically present with myelodysplastic syndrome,…”
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Sparse production but preferential incorporation of recently produced naïve T cells in the human peripheral pool
Published in Proceedings of the National Academy of Sciences - PNAS (22-04-2008)“…In mice, recent thymic emigrants (RTEs) make up a large part of the naïve T cell pool and have been suggested to be a distinct short-lived pool. In humans,…”
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Modulation of Signal Strength Switches Notch from an Inducer of T Cells to an Inducer of ILC2
Published in Frontiers in immunology (01-01-2013)“…Innate lymphoid cells (ILCs) are emerging key players of the immune system with close lineage relationship to T cells. ILC2 play an important role in…”
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Human ectoenzyme-expressing ILC3: immunosuppressive innate cells that are depleted in graft-versus-host disease
Published in Blood advances (26-11-2019)“…Allogeneic hematopoietic stem cell transplantation (allo-HSCT) is often associated with chemotherapy- and radiotherapy-induced host tissue damage, leading to…”
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Taste and smell disturbances in patients with chronic oral graft vs. host disease: An observational study
Published in Frontiers in oral health (09-09-2022)“…Background A common complication of allogeneic hematopoietic stem cell transplantation (alloHSCT) is chronic oral graft vs. host disease (cGvHD). Oral cGvHD…”
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Reconciling Longitudinal Naive T-Cell and TREC Dynamics during HIV-1 Infection
Published in PloS one (24-03-2016)“…Naive T cells in untreated HIV-1 infected individuals have a reduced T-cell receptor excision circle (TREC) content. Previous mathematical models have…”
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Long-Term Analysis of Resilience of the Oral Microbiome in Allogeneic Stem Cell Transplant Recipients
Published in Microorganisms (Basel) (29-03-2022)“…Stem cell transplantation (SCT) is associated with oral microbial dysbiosis. However, long-term longitudinal data are lacking. Therefore, this study aimed to…”
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Gut microbiome in allogeneic HCT survivors: The insults are gone but the damage lingers
Published in British journal of haematology (01-05-2023)“…The gut microbiome is an important regulator of health and disease. The report by Hino et al. suggests that damage to the microbiome, inflicted before and soon…”
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Naïve and Memory Cell Turnover as Drivers of CCR5-to-CXCR4 Tropism Switch in Human Immunodeficiency Virus Type 1: Implications for Therapy
Published in Journal of Virology (01-01-2006)“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Patient-derived antibody recognizes a unique CD43 epitope expressed on all AML and has antileukemia activity in mice
Published in Blood advances (22-08-2017)“…Immunotherapy has proven beneficial in many hematologic and nonhematologic malignancies, but immunotherapy for acute myeloid leukemia (AML) and myelodysplastic…”
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