Search Results - "Hazen, Jennie E."

Non-lethal Inhibition of Gut Microbial Trimethylamine Production for the Treatment of Atherosclerosis by Wang, Zeneng, Roberts, Adam B., Buffa, Jennifer A., Levison, Bruce S., Zhu, Weifei, Org, Elin, Gu, Xiaodong, Huang, Ying, Zamanian-Daryoush, Maryam, Culley, Miranda K., DiDonato, Anthony J., Fu, Xiaoming, Hazen, Jennie E., Krajcik, Daniel, DiDonato, Joseph A., Lusis, Aldons J., Hazen, Stanley L.

“…Trimethylamine (TMA) N-oxide (TMAO), a gut-microbiota-dependent metabolite, both enhances atherosclerosis in animal models and is associated with…”
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Functional role of the type 1 pilus rod structure in mediating host-pathogen interactions by Spaulding, Caitlin N, Schreiber, 4th, Henry Louis, Zheng, Weili, Dodson, Karen W, Hazen, Jennie E, Conover, Matt S, Wang, Fengbin, Svenmarker, Pontus, Luna-Rico, Areli, Francetic, Olivera, Andersson, Magnus, Hultgren, Scott, Egelman, Edward H

“…Uropathogenic (UPEC), which cause urinary tract infections (UTI), utilize type 1 pili, a chaperone usher pathway (CUP) pilus, to cause UTI and colonize the…”
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Measurement of trimethylamine-N-oxide by stable isotope dilution liquid chromatography tandem mass spectrometry by Wang, Zeneng, Levison, Bruce S., Hazen, Jennie E., Donahue, Lillian, Li, Xin-Min, Hazen, Stanley L.

“…Trimethylamine-N-oxide (TMAO) levels in blood predict future risk for major adverse cardiac events including myocardial infarction, stroke, and death. Thus,…”
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Prognostic Value of Elevated Levels of Intestinal Microbe-Generated Metabolite Trimethylamine-N-Oxide in Patients With Heart Failure: Refining the Gut Hypothesis by TANG, W. H. Wilson, ZENENG WANG, YIYING FAN, LEVISON, Bruce, HAZEN, Jennie E, DONAHUE, Lillian M, YUPING WU, HAZEN, Stanley L

“…Altered intestinal function is prevalent in patients with heart failure (HF), but its role in adverse outcomes is unclear. This study investigated the…”
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Catheterization of mice triggers resurgent urinary tract infection seeded by a bladder reservoir of Acinetobacter baumannii by Hazen, Jennie E, Di Venanzio, Gisela, Hultgren, Scott J, Feldman, Mario F

“…The antibiotic-resistant bacterium is a leading cause of hospital-associated infections. Despite surveillance and infection control efforts, new strains are…”
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Miltefosine increases macrophage cholesterol release and inhibits NLRP3-inflammasome assembly and IL-1β release by Iacano, Amanda J., Lewis, Harvey, Hazen, Jennie E., Andro, Heather, Smith, Jonathan D., Gulshan, Kailash

“…Miltefosine is an FDA approved oral drug for treating cutaneous and visceral leishmaniasis. Leishmania is a flagellated protozoa, which infects and…”
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Prognostic Value of Elevated Levels of Intestinal Microbe-Generated Metabolite Trimethylamine- N -Oxide in Patients With Heart Failure by Tang, W.H. Wilson, MD, Wang, Zeneng, PhD, Fan, Yiying, PhD, Levison, Bruce, PhD, Hazen, Jennie E, Donahue, Lillian M, Wu, Yuping, PhD, Hazen, Stanley L., MD, PhD

“…Abstract Background Altered intestinal function is prevalent in patients with heart failure (HF), but its role in adverse outcomes is unclear. Objectives This…”
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An abundant dysfunctional apolipoprotein A1 in human atheroma by Huang, Ying, DiDonato, Joseph A, Levison, Bruce S, Schmitt, Dave, Li, Lin, Wu, Yuping, Buffa, Jennifer, Kim, Timothy, Gerstenecker, Gary S, Gu, Xiaodong, Kadiyala, Chandra S, Wang, Zeneng, Culley, Miranda K, Hazen, Jennie E, DiDonato, Anthony J, Fu, Xiaoming, Berisha, Stela Z, Peng, Daoquan, Nguyen, Truc T, Liang, Shaohong, Chuang, Chia-Chi, Cho, Leslie, Plow, Edward F, Fox, Paul L, Gogonea, Valentin, Tang, W H Wilson, Parks, John S, Fisher, Edward A, Smith, Jonathan D, Hazen, Stanley L

“…Although numerous studies have demonstrated anti-atherosclerotic effects of high-density lipoprotein (HDL), drugs that elevate HDL cholesterol levels have…”
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