Search Results - "Hazel, Tom"
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Human Cortical Neural Stem Cells Expressing Insulin‐Like Growth Factor‐I: A Novel Cellular Therapy for Alzheimer's Disease
Published in Stem cells translational medicine (01-03-2016)“…Alzheimer's disease (AD) is the most prevalent age‐related neurodegenerative disorder and a leading cause of dementia. Current treatment fails to modify…”
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Long‐term Phase 1/2 intraspinal stem cell transplantation outcomes in ALS
Published in Annals of clinical and translational neurology (01-06-2018)“…Objective Intraspinal human spinal cord‐derived neural stem cell (HSSC) transplantation is a potential therapy for amyotrophic lateral sclerosis (ALS);…”
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Spinal parenchymal occupation by neural stem cells after subpial delivery in adult immunodeficient rats
Published in Stem cells translational medicine (01-02-2020)“…Neural precursor cells (NSCs) hold great potential to treat a variety of neurodegenerative diseases and injuries to the spinal cord. However, current delivery…”
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Feasibility of Human Neural Stem Cell Transplantation for the Treatment of Acute Subdural Hematoma in a Rat Model: A Pilot Study
Published in Frontiers in neurology (12-02-2019)“…Human neural stem cells (hNSCs) transplantation in several brain injury models has established their therapeutic potential. However, the feasibility of hNSCs…”
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Transplantation of spinal cord–derived neural stem cells for ALS: Analysis of phase 1 and 2 trials
Published in Neurology (26-07-2016)“…OBJECTIVE:To test the safety of spinal cord transplantation of human stem cells in patients with amyotrophic lateral sclerosis (ALS) with escalating doses and…”
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Potential of Human Neural Stem Cell Transplantation to Treat Acute Subdural Hematoma
Published in Neurosurgery (01-09-2019)Get full text
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Pig models of neurodegenerative disorders: Utilization in cell replacement-based preclinical safety and efficacy studies
Published in Journal of comparative neurology (1911) (15-08-2014)“…ABSTRACT An important component for successful translation of cell replacement‐based therapies into clinical practice is the utilization of large animal models…”
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