Search Results - "Hayward, C P"

Results of a worldwide survey on the assessment of platelet function by light transmission aggregometry: a report from the platelet physiology subcommittee of the SSC of the ISTH by CATTANEO, M., HAYWARD, C. P .M., MOFFAT, K. A., PUGLIANO, M. T., LIU, Y., MICHELSON, A. D.

“…Background: Light transmission aggregometry (LTA) is the most common method used in clinical and research laboratories to assess platelet function. However,…”
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Evaluation of an automated method for measuring von Willebrand factor activity in clinical samples without ristocetin by Graf, L., Moffat, K. A., Carlino, S. A., Chan, A. K. C., Iorio, A., Giulivi, A., Hayward, C. P. M.

“…Summary Introduction The development of an automated, von Willebrand factor (VWF) activity assay, Innovance® VWF Ac (VWF:Ac), which measures VWF binding to the…”
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How I investigate for bleeding disorders by Hayward, C. P. M.

“…Introduction Laboratory investigations for bleeding disorders are warranted when an individual has a personal and/or family history of bleeding, and/or…”
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Recommendations for the standardization of light transmission aggregometry: a consensus of the working party from the platelet physiology subcommittee of SSC/ISTH by Cattaneo, M., Cerletti, C., Harrison, P., Hayward, C. P. M., Kenny, D., Nugent, D., Nurden, P., Rao, A. K., Schmaier, A. H., Watson, S. P., Lussana, F., Pugliano, M. T., Michelson, A. D.

“…Light transmission aggregometry (LTA) is the most common method used to assess platelet function. However, there is no universal standard for its performance…”
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Diagnosis of suspected inherited platelet function disorders: results of a worldwide survey by Gresele, P., Harrison, P., Bury, L., Falcinelli, E., Gachet, C., Hayward, C. P., Kenny, D., Mezzano, D., Mumford, A. D., Nugent, D., Nurden, A. T., Orsini, S., Cattaneo, M.

“…Summary Background Diagnosis of inherited platelet function disorders (IPFDs) is important for appropriate management and to improve epidemiologic and clinical…”
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Insights into abnormal hemostasis in the Quebec platelet disorder from analyses of clot lysis by DIAMANDIS, M., ADAM, F., KAHR, W. H. A., WANG, P., CHORNEYKO, K. A., ARSENAULT, A. L., RIVARD, G. E., HAYWARD, C. P. M.

“…Background: The Quebec platelet disorder (QPD) is inherited and characterized by delayed‐onset bleeding following hemostatic challenge. Other characteristics…”
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Platelet function analyzer (PFA)‐100® closure time in the evaluation of platelet disorders and platelet function by HAYWARD, C. P. M., HARRISON, P., CATTANEO, M., ORTEL, T. L., RAO, A. K.

“…Background: Closure time (CT), measured by platelet function analyzer (PFA‐100®) device, is now available to the clinical laboratory as a possible alternative…”
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Electron microscopy examination of platelet whole mount preparations to quantitate platelet dense granule numbers: Implications for diagnosing suspected platelet function disorders due to dense granule deficiency by Brunet, J. G., Iyer, J. K., Badin, M. S., Graf, L., Moffat, K. A., Timleck, M., Spitzer, E., Hayward, C. P. M.

“…Introduction Dense granule (DG) deficiency (DGD) is a feature of some platelet function disorders (PFD) with a prevalence similar to von Willebrand disease…”
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Diagnostic utility of light transmission platelet aggregometry: results from a prospective study of individuals referred for bleeding disorder assessments by HAYWARD, C. P. M., PAI, M., LIU, Y., MOFFAT, K. A., SEECHARAN, J., WEBERT, K. E., COOK, R. J., HEDDLE, N. M.

“…Background: Light transmission aggregometry (LTA) is commonly performed to assess individuals for bleeding disorders. Objectives: The goal was to evaluate the…”
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Sera From Patients With Heparin-Induced Thrombocytopenia Generate Platelet-Derived Microparticles With Procoagulant Activity: An Explanation for the Thrombotic Complications of Heparin-Induced Thrombocytopenia by Warkentin, Theodore E., Hayward, Catherine P.M., Boshkov, Lynn K., Santos, Aurelio V., Sheppard, Jo-Ann I., Bode, Arthur P., Kelton, John G.

“…Heparin-induced thrombocytopenia is characterized by moderate thrombocytopenia and thrombotic complications, whereas quinine/quinidine-induced thrombocytopenia…”
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Genomic approaches to bleeding disorders by Peyvandi, F., Hayward, C. P. M.

“…The genes encoding the coagulation factors were characterized over two decades ago. Since then, significant progress has been made in the genetic diagnosis of…”
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Update from the President of the International Society for Laboratory Hematology initiatives to promote education, mentorship, best practices, and collaboration by Hayward, C. P. M.

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Immunoglobulin G from patients with heparin-induced thrombocytopenia binds to a complex of heparin and platelet factor 4 by KELTON, J. G, SMITH, J. W, WARKENTIN, T. E, HAYWARD, C. P. M, DENOMME, G. A, HORSEWOOD, P

“…Heparin-induced thrombocytopenia (HIT) is an important complication of heparin therapy. Although there is general agreement that platelet activation in vitro…”
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Update from the President on the International Society for Laboratory Hematology, including initiatives to promote education and best practices by Hayward, C. P. M.

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Laboratory testing for bleeding disorders: strategic uses of high and low-yield tests by Hayward, C. P. M., Moffat, K. A.

“…Summary Laboratory testing is essential for diagnosing bleeding disorders. The tests and panels that laboratories currently use for bleeding disorder…”
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Variability in platelet dense granule adenosine triphosphate release findings amongst patients tested multiple times as part of an assessment for a bleeding disorder by Badin, M. S., Graf, L., Iyer, J. K., Moffat, K. A., Seecharan, J. L., Hayward, C. P. M.

“…Summary Introduction Lumi‐aggregometry quantification of platelet dense granule adenosine triphosphate (ATP) release is commonly used for diagnosing platelet…”
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Molecular phenotype and bleeding risks of an inherited platelet disorder in a family with a RUNX1 frameshift mutation by Badin, M. S., Iyer, J. K., Chong, M., Graf, L., Rivard, G. E., Waye, J. S., Paterson, A. D., Pare, G., Hayward, C. P. M.

“…Introduction Inherited defects in RUNX1 are important causes of platelet function disorders. Aim Our goals were to evaluate RUNX1‐related platelet disorders…”
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Thrombopoietin levels in Quebec platelet disorder—Implications for the mechanism of thrombocytopenia by Hayward, C. P. M., Tasneem, S., Rivard, G. E.

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Congenital platelet disorders: overview of their mechanisms, diagnostic evaluation and treatment by HAYWARD, C. P. M., RAO, A. K., CATTANEO, M.

“…The bleeding problems associated with common and rare inherited platelet disorders illustrate the importance of platelets to normal haemostasis. At sites of…”
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Assembly and evaluation of an inventory of guidelines that are available to support clinical hematology laboratory practice by Hayward, C. P. M., Moffat, K. A., George, T. I., Proytcheva, M.

“…Summary Introduction Practice guidelines provide helpful support for clinical laboratories. Our goal was to assemble an inventory of publically listed…”
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