Search Results - "Hayward, Alison M."
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Endoscopically Injectable Shear‐Thinning Hydrogels Facilitating Polyp Removal
Published in Advanced science (01-10-2019)“…Submucosal elevation, the process of instilling material in the submucosal space for separation of the surface mucosa and deeper muscularis layer, is a…”
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Kirigami-inspired stents for sustained local delivery of therapeutics
Published in Nature materials (01-08-2021)“…Implantable drug depots have the capacity to locally meet therapeutic requirements by maximizing local drug efficacy and minimizing potential systemic side…”
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Computationally guided high-throughput design of self-assembling drug nanoparticles
Published in Nature nanotechnology (01-06-2021)“…Nanoformulations of therapeutic drugs are transforming our ability to effectively deliver and treat a myriad of conditions. Often, however, they are complex to…”
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Gastrointestinal Delivery of an mRNA Vaccine Using Immunostimulatory Polymeric Nanoparticles
Published in The AAPS journal (17-08-2023)“…mRNA vaccines can be translated into protein antigens, in vivo , to effectively induce humoral and cellular immunity against these proteins. While current mRNA…”
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Temperature-responsive biometamaterials for gastrointestinal applications
Published in Science translational medicine (17-04-2019)“…We hypothesized that ingested warm fluids could act as triggers for biomedical devices. We investigated heat dissipation throughout the upper gastrointestinal…”
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Human embryonic stem cell-derived microvascular grafts for cardiac tissue preservation after myocardial infarction
Published in Biomaterials (01-02-2011)“…Abstract We present use of a synthetic, injectable matrix metalloproteinase (MMP)- responsive, bioactive hydrogel as an in situ forming scaffold to deliver…”
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Kirigami-inspired stents for sustained local delivery of therapeutics
Published in Nature materials (14-06-2021)Get full text
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A vibrating ingestible bioelectronic stimulator modulates gastric stretch receptors for illusory satiety
Published in Science advances (22-12-2023)“…Effective therapies for obesity require invasive surgical and endoscopic interventions or high patient adherence, making it challenging for patients with…”
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Accuracy of cardiac ablation catheter guidance by means of a single equivalent moving dipole inverse algorithm to identify sites of origin of cardiac electrical activation
Published in Journal of interventional cardiac electrophysiology (01-09-2020)“…We have developed a system that could potentially be used to identify the site of origin of ventricular tachycardia (VT) and to guide a catheter to that site…”
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Closed-loop automated drug infusion regulator: A clinically translatable, closed-loop drug delivery system for personalized drug dosing
Published in Med (New York, N.Y. : Online) (12-07-2024)“…Dosing of chemotherapies is often calculated according to the weight and/or height of the patient or equations derived from these, such as body surface area…”
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The Single Equivalent Moving Dipole Model Does Not Require Spatial Anatomical Information to Determine Cardiac Sources of Activation
Published in IEEE journal of biomedical and health informatics (01-01-2014)“…Radio-frequency catheter ablation (RCA) is an established treatment for ventricular tachycardia (VT). A key feature of the RCA procedure is the need for a…”
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Comparison of Tetraploid Blastocyst Microinjection of Outbred Crl:CD1(ICR), Hybrid B6D2F1/Tac, and Inbred C57BL/6NTac Embryos for Generation of Mice Derived from Embryonic Stem Cells
Published in Comparative medicine (01-04-2008)“…Embryo electrofusion and tetraploid blastocyst microinjection is a modification of the traditional embryonic stem cell (ES cell)- based method to generate…”
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Secure and Stable Wireless Communication for an Ingestible Device
Published in 2023 45th Annual International Conference of the IEEE Engineering in Medicine & Biology Society (EMBC) (01-01-2023)“…Wireless communication enables an ingestible device to send sensor information and support external on-demand operation while in the gastrointestinal (GI)…”
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A review of interventions for noncommunicable diseases in humanitarian emergencies in low- and middle-income countries
Published in American journal of disaster medicine (01-10-2022)“…Noncommunicable diseases (NCDs) are of increasing prevalence in low- and middle-income countries (LMICs), affected by disasters. Humanitarian actors are…”
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