Assessment of skin photoaging with reflectance confocal microscopy

Increased interest in antiaging methods, mandates a development of reliable noninvasive technique to assess skin aging. In this study, we aimed to determine the effects of photoaging at histopathologic resolution by means of reflectance confocal microscopy. The sun-exposed malar area, the anterior a...

Full description

Saved in:

Bibliographic Details
Published in:	Skin research and technology Vol. 20; no. 3; p. 363
Main Authors:	Haytoglu, N S Kutlu, Gurel, M S, Erdemir, A, Falay, T, Dolgun, A, Haytoglu, T G
Format:	Journal Article
Language:	English
Published:	England 01-08-2014
Subjects:	Adult Aged Aged, 80 and over Aging - physiology Dermoscopy - methods Female Humans Image Interpretation, Computer-Assisted - methods Male Microscopy, Confocal - methods Microscopy, Interference - methods Middle Aged Reproducibility of Results Sensitivity and Specificity Skin - cytology Skin - radiation effects Skin Aging - physiology Sunlight reflectance confocal microscopy noninvasive imaging skin aging elastosis collagen changes photoaging
Online Access:	Get more information
Tags:	Add Tag No Tags, Be the first to tag this record!

Description
Summary:	Increased interest in antiaging methods, mandates a development of reliable noninvasive technique to assess skin aging. In this study, we aimed to determine the effects of photoaging at histopathologic resolution by means of reflectance confocal microscopy. The sun-exposed malar area, the anterior aspect of ear lobule, and the sun-protected posterior aspect of ear lobule had been evaluated in 120 volunteers from different age groups over 10 previously reported and new confocal parameters for skin aging. The sun-exposed areas revealed more frequent irregular honeycomb pattern, polycylic papillary contours, coarse collagen, huddled collagen, curled bright structures with higher epidermal thickness, and furrow depth values. However, the incidence of thin reticulated collagen and the number of dermal papillae were statistically higher on the sun-protected posterior aspect of ear lobule. Reflectance confocal microscopy is a reliable diagnostic technique for evaluation of skin photoaging with objective criteria. With the new emerging compact models it is possible to scan even the least accessible body parts with no discomfort to the patient, which offers the possibility to assess the effect of antiaging applications and to identify early signs of solar damage in cosmetically sensitive areas.
ISSN:	1600-0846
DOI:	10.1111/srt.12127