Search Results - "Haystead, T A"

Fluorescent-Linked Enzyme Chemoproteomic Strategy (FLECS) for Identifying HSP70 Inhibitors by Haystead, T A J

“…Activation of the heat shock response, and in particular upregulation of stress-inducible Hsp70, herein referred to as Hsp70i, in newly transformed cells,…”
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PHAS-I as a Link Between Mitogen-Activated Protein Kinase and Translation Initiation by Lin, Tai-An, Kong, Xianming, Timothy A. J. Haystead, Pause, Arnim, Belsham, Graham, Sonenberg, Nahum, Lawrence, John C.

“…PHAS-I is a heat-stable protein (relative molecular mass $\approx$12,400) found in many tissues. It is rapidly phosphorylated in rat adipocytes incubated with…”
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Effects of the tumour promoter okadaic acid on intracellular protein phosphorylation and metabolism by Haystead, T. A. J, Sim, A. T. R, Carling, D, Honnor, R. C, Tsukitani, Y, Cohen, P, Hardie, D. G

“…Okadaic acid is a polyether derivative of 38-carbon fatty acid, and is implicated as the causative agent of diarrhetic shellfish poisoning. It is a potent…”
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Activation of Mitogen-Activated Protein Kinase Kinase by v-Raf in NIH 3T3 Cells and in Vitro by Dent, Paul, Haser, Wayne, Timothy A. J. Haystead, Vincent, Leigh Ann, Roberts, Thomas M., Sturgill, Thomas W.

“…Mitogen-activated protein (MAP) kinases are 42- and 44-kD serine-threonine protein kinases that are activated by tyrosine and threonine phosphorylation in…”
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Insulin and diabetes cause reciprocal changes in the association of eIF-4E and PHAS-I in rat skeletal muscle by Kimball, S.R. (Pennsylvania State University, Hershey, PA.), Jefferson, L.S, Fadden, P, Haystead, T.A.J, Lawrence, J.C. Jr

“…We have investigated the roles of eukaryotic initiation factor 4E (eIF-4E), the cap-binding protein, and the translational regulator, PHAS-I, in the effects of…”
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Molecular Structure of a Protein-Tyrosine/Threonine Kinase Activating p42 Mitogen-Activated Protein (MAP) Kinase: MAP Kinase Kinase by Wu, Jie, Harrison, Jeffrey K., Vincent, Leigh Ann, Haystead, Claire, Timothy A. J. Haystead, Michel, Hanspeter, Hunt, Donald F., Lynch, Kevin R., Sturgill, Thomas W.

“…MAP kinases p42mapkand p44mapkparticipate in a protein kinase cascade(s) important for signaling in many cell types and contexts. Both MAP kinases are…”
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Phosphorylation of caldesmon by mitogen-activated protein kinase with no effect on Ca2+ sensitivity in rabbit smooth muscle by Nixon, G F, Iizuka, K, Haystead, C M, Haystead, T A, Somlyo, A P, Somlyo, A V

“…1. Recombinant, activated mitogen-activated protein kinase (3.3 microM; p42mapk) phosphorylated caldesmon in phasic (rabbit portal vein) and tonic (rabbit…”
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Okadaic acid mimics the action of insulin in stimulating protein kinase activity in isolated adipocytes. The role of protein phosphatase 2a in attenuation of the signal by Haystead, T A, Weiel, J E, Litchfield, D W, Tsukitani, Y, Fischer, E H, Krebs, E G

“…Treatment of adipocytes with okadaic acid (a specific inhibitor of type 1 and 2a protein phosphatases) resulted in a rapid 8-10-fold stimulation of cell…”
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Insulin activates a novel adipocyte mitogen-activated protein kinase kinase kinase that shows rapid phasic kinetics and is distinct from c-Raf by HAYSTEAD, C. M. M, GREGORY, P, SHIRAZI, A, FADDEN, P, MOSSE, C, DENT, P, HAYSTEAD, T. A. J

“…Treatment of adipocytes with insulin or phorbol 12-myristate 13-acetate (PMA) results in transient activation of mitogen-activated protein kinase kinase (MEK)…”
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Activation of messenger-independent protein kinases in wild-type and phorbol ester-resistant EL4 thymoma cells by MEIER, K. E, LICCIARDI, K. A, HAYSTEAD, T. A. J, KREBS, E. G

“…Phorbol esters, acting via activation of the protein kinase C family of protein serine/threonine kinases, are able to exert profound effects on various…”
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Human Cytidine Triphosphate Synthetase 1 Interacting Proteins by Higgins, M. J., Loiselle, D., Haystead, T. A., Graves, L. M.

“…We investigated the interacting proteins and intracellular localization of CTP synthetase 1 (CTPS1) in mammalian cells. CTPS1 interacted with a GST- peptidyl…”
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Purification and characterization of the mammalian myosin light chain phosphatase holoenzyme. The differential effects of the holoenzyme and its subunits on smooth muscle by Shirazi, A, Iizuka, K, Fadden, P, Mosse, C, Somlyo, A P, Somlyo, A V, Haystead, T A

“…We have purified to homogeneity from the myofibrillar fraction of pig bladder a mammalian heterotrimeric form of PP-1, SMPP-1M. Purified pig bladder SMPP-1M is…”
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Phosphorylation of PHAS-I by mitogen-activated protein (MAP) kinase. Identification of a site phosphorylated by MAP kinase in vitro and in response to insulin in rat adipocytes by T A Haystead, C M Haystead, C Hu, T A Lin, J C Lawrence, Jr

“…PHAS-I is a heat- and acid-stable protein that is phosphorylated on Ser/Thr residues in response to insulin and growth factors. To investigate the…”
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Use of okadaic acid to inhibit protein phosphatases in intact cells by Hardie, D G, Haystead, T A, Sim, A T

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Efficient detection of RNA-protein interactions using tethered RNAs by Iioka, Hidekazu, Loiselle, David, Haystead, Timothy A, Macara, Ian G

“…The diverse localization of transcripts in cells suggests that there are many specific RNA-protein interactions that have yet to be identified. Progress has…”
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Changes in Magnetization Transfer MRI Correlate with Spreading Depression-Induced Astroglial Reactivity and Increased Protein Expression in Mice by Lascola, Christopher D, Song, Allen W, Haystead, Timothy A, Warner, David S, Verleysen, Katleen, Freed, Tiffany A, Provenzale, James M

“…Gliosis refers to a range of glial cell transformations that vary according to specific brain pathologic states. Disease, however, is not a prerequisite for…”
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Functional expression of a MAP kinase kinase in COS cells and recognition by an anti-STE7/byr1 antibody by HAYSTEAD, C. M. M, JIE WU, GREGORY, P, STURGILL, T. W, HAYSTEAD, T. A. J

“…Mitogen-activated protein (MAP) kinases p42mapk and p44mapk are activated by dual tyrosine and threonine phosphorylation in vivo. Both MAPKs are phosphorylated…”
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Regulatory Interactions between the Reg1-Glc7 Protein Phosphatase and the Snf1 Protein Kinase by Sanz, Pascual, Alms, Geoffrey R., Haystead, Timothy A. J., Carlson, Marian

“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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C-terminal Repeat Domain Kinase I Phosphorylates Ser2 and Ser5 of RNA Polymerase II C-terminal Domain Repeats by Jones, Janice C., Phatnani, Hemali P., Haystead, Timothy A., MacDonald, Justin A., Alam, S. Munir, Greenleaf, Arno L.

“…The C-terminal repeat domain (CTD) of the largest subunit of RNA polymerase II is composed of tandem heptad repeats with consensus sequence…”
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γ-Phosphate-linked ATP-sepharose for the affinity purification of protein kinases : rapid purification to homogeneity of skeletal muscle mitogen-activated protein kinase kinase by HAYSTEAD, C. M. M, GREGORY, P, STURGILL, T. W, HAYSTEAD, T. A. J

“…Recently, Sowadski and colleagues [Knighton, D.R., Zheng, J., Eyck, L.F.T., Ashford, V.A., Xuong, N., Taylor, S.S. & Sowadski, J.M. (1991) Science 407,…”
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