Search Results - "Hays, Lori"

Palmitate Inhibits Insulin Gene Expression by Altering PDX-1 Nuclear Localization and Reducing MafA Expression in Isolated Rat Islets of Langerhans by Hagman, Derek K., Hays, Lori B., Parazzoli, Susan D., Poitout, Vincent

“…Abnormalities in lipid metabolism have been proposed as contributing factors to both defective insulin secretion from the pancreatic beta cell and peripheral…”
Get full text

Insulin Secretory Deficiency and Glucose Intolerance in Rab3A Null Mice by Yaekura, Kazuro, Julyan, Richard, Wicksteed, Barton L, Hays, Lori B, Alarcon, Cristina, Sommers, Scott, Poitout, Vincent, Baskin, Denis G, Wang, Yong, Philipson, Louis H, Rhodes, Christopher J

“…Insulin secretory dysfunction of the pancreatic β-cell in type-2 diabetes is thought to be due to defective nutrient sensing and/or deficiencies in the…”
Get full text

Direct Imaging Shows That Insulin Granule Exocytosis Occurs by Complete Vesicle Fusion by Ma, Li, Bindokas, Vytautas P., Kuznetsov, Andrey, Rhodes, Christopher, Hays, Lori, Edwardson, J. Michael, Ueda, Kazuya, Steiner, Donald F., Philipson, Louis H.

“…Confocal imaging of GFP-tagged secretory granules combined with the use of impermeant extracellular dyes permits direct observation of insulin packaged in…”
Get full text

Syncollin inhibits regulated corticotropin secretion from AtT-20 cells through a reduction in the secretory vesicle population by Wäsle, Barbara, Hays, Lori B, Rhodes, Christopher J, Edwardson, J Michael

“…Syncollin is a 13 kDa protein that is highly expressed in the exocrine pancreas. Syncollin normally exists as a doughnut-shaped homo-oligomer (quite probably a…”
Get full text

A fluorescent timer reporter enables sorting of insulin secretory granules by age by Yau, Belinda, Hays, Lori, Liang, Cassandra, Laybutt, D. Ross, Thomas, Helen E., Gunton, Jenny E., Williams, Lindy, Hawthorne, Wayne J., Thorn, Peter, Rhodes, Christopher J., Kebede, Melkam A.

“…Within the pancreatic β-cells, insulin secretory granules (SGs) exist in functionally distinct pools, displaying variations in motility as well as docking and…”
Get full text

A fluorescent timer reporter enables sorting of insulin secretory granules by age by Yau, Belinda, Hays, Lori, Liang, Cassandra, Laybutt, D Ross, Thomas, Helen E, Gunton, Jenny E, Williams, Lindy, Hawthorne, Wayne J, Thorn, Peter, Rhodes, Christopher J, Kebede, Melkam A

“…Within the pancreatic β-cells, insulin secretory granules (SGs) exist in functionally distinct pools, displaying variations in motility as well as docking and…”
Get full text

Two-hybrid system for characterization of protein-protein interactions in E. coli by Hays, L B, Chen, Y S, Hu, J C

“…The yeast two-hybrid system has been used to characterize many protein-protein interactions. A two-hybrid system for E. coli was constructed in which one…”
Get full text

Ca2+-dependent dephosphorylation of kinesin heavy chain on beta-granules in pancreatic beta-cells. Implications for regulated beta-granule transport and insulin exocytosis by Donelan, Matthew J., Morfini, Gerardo, Julyan, Richard, Sommers, Scott, Hays, Lori, Kajio, Hiroshi, Briaud, Isabelle, Easom, Richard A., Molkentin, Jeffery D., Brady, Scott T., Rhodes, Christopher J.

“…The specific biochemical steps required for glucose-regulated insulin exocytosis from beta-cells are not well defined. Elevation of glucose leads to increases…”
Get full text

FXYD6 Directs [beta]-Granule Transport to Active Zones of Exocytosis by Hays, Lori B, McCuaig, Jill F, Rhodes, Christopher J

Get full text

Ca2+-dependent Dephosphorylation of Kinesin Heavy Chain on β-Granules in Pancreatic β-Cells by Matthew J. Donelan, Gerardo Morfini, Richard Julyan, Scott Sommers, Lori Hays, Hiroshi Kajio, Isabelle Briaud, Richard A. Easom, Jeffery D. Molkentin, Scott T. Brady, Christopher J. Rhodes

“…The specific biochemical steps required for glucose-regulated insulin exocytosis from β-cells are not well defined. Elevation of glucose leads to increases in…”
Get full text

Ca2+-dependent Dephosphorylation of Kinesin Heavy Chain on β-Granules in Pancreatic β-Cells by Donelan, Matthew J., Morfini, Gerardo, Julyan, Richard, Sommers, Scott, Hays, Lori, Kajio, Hiroshi, Briaud, Isabelle, Easom, Richard A., Molkentin, Jeffery D., Brady, Scott T., Rhodes, Christopher J.

“…The specific biochemical steps required for glucose-regulated insulin exocytosis from β-cells are not well defined. Elevation of glucose leads to increases in…”
Get full text