Search Results - "Haynes‐Williams, Vanessa"
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Dietary fatty acid oxidation is decreased in non‐alcoholic fatty liver disease: A palmitate breath test study
Published in Liver international (01-03-2020)“…Background & Aim Hepatic fat excess in non‐alcoholic fatty liver disease (NAFLD) reflects an imbalance between fat accumulation and disposal. Conflicting data…”
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Journal Article -
2
Oral prenylation inhibition with lonafarnib in chronic hepatitis D infection: a proof-of-concept randomised, double-blind, placebo-controlled phase 2A trial
Published in The Lancet infectious diseases (01-10-2015)“…Summary Background Therapies for chronic hepatitis delta virus (HDV) infection are unsatisfactory. Prenylation is essential for HDV and inhibition abrogates…”
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Journal Article -
3
Understanding early serum hepatitis D virus and hepatitis B surface antigen kinetics during pegylated interferon‐alpha therapy via mathematical modeling
Published in Hepatology (Baltimore, Md.) (01-12-2014)“…There is little information on the early kinetics of hepatitis delta virus (HDV) and hepatitis B surface antigen (HBsAg) during interferon‐α therapy. Here a…”
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Journal Article -
4
Ribavirin Improves Early Responses to Peginterferon Through Improved Interferon Signaling
Published in Gastroenterology (New York, N.Y. 1943) (01-07-2010)“…Background & Aims The therapeutic mechanisms of ribavirin for hepatitis C are unclear. Microarray analyses have shown that ribavirin increases induction of…”
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Journal Article -
5
Postprandial Plasma Lipidomics Reveal Specific Alteration of Hepatic-derived Diacylglycerols in Nonalcoholic Fatty Liver Disease
Published in Gastroenterology (New York, N.Y. 1943) (01-06-2022)“…Hepatic energy metabolism is a dynamic process modulated by multiple stimuli. In nonalcoholic fatty liver disease (NAFLD), human studies typically focus on the…”
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Journal Article -
6
Postprandial plasma lipidomics reveal specific alteration of hepatic-derived diacylglycerols in non-alcoholic fatty liver disease
Published in Gastroenterology (New York, N.Y. 1943) (10-03-2022)“…In humans with NAFLD and in mouse models of the disease, mixed-meal leads to selective secretion of diacylglycerols (DAG) from the liver to the plasma through…”
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Journal Article -
7
Long‐term therapy of chronic delta hepatitis with peginterferon alfa
Published in Alimentary pharmacology & therapeutics (01-07-2014)“…Summary Background Chronic delta hepatitis virus (HDV) infection rapidly progresses to cirrhosis. Treatment with peginterferon for up to 2 years is often…”
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Journal Article -
8
Complications of percutaneous liver biopsy with Klatskin needles: a 36‐year single‐centre experience
Published in Alimentary pharmacology & therapeutics (01-03-2017)“…Summary Background Liver biopsy is the gold standard in evaluating liver diseases but is susceptible to complications. Safety data on aspiration needle…”
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Journal Article -
9
Spectrum of Liver Disease in Hepatitis B Virus (HBV) Patients Co-infected with Human Immunodeficiency Virus (HIV): Results of the HBV-HIV Cohort Study
Published in The American journal of gastroenterology (01-05-2019)“…Because most HBV/HIV co-infected patients on combination antiretroviral therapy (cART) have suppressed HBV DNA and normal liver enzymes, the histologic…”
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Journal Article -
10
Patient‐reported outcomes in a large North American cohort living with chronic hepatitis B virus: a cross‐sectional analysis
Published in Alimentary pharmacology & therapeutics (01-02-2020)“…Summary Background Patient‐reported outcomes (PROs) such as health‐related quality of life (HRQoL) and symptoms associated with chronic hepatitis B viral (HBV)…”
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Journal Article -
11
Liver injury is associated with mortality in sickle cell disease
Published in Alimentary pharmacology & therapeutics (01-10-2015)“…Summary Background Increased life expectancy in sickle cell disease (SCD) has resulted in greater recognition of the consequences of repeated intravascular…”
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Journal Article -
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Long‐term outcome of chronic hepatitis C after sustained virological response to interferon‐based therapy
Published in Alimentary pharmacology & therapeutics (01-05-2013)“…Summary Background Although the short‐term benefits of a sustained virological response (SVR) to interferon‐based therapies of chronic hepatitis C (CHC) are…”
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Journal Article -
13
Understanding early serum hepatitis D virus and HBsAg kinetics during pegylated interferon-alfa therapy via mathematical modeling
Published in Hepatology (Baltimore, Md.) (27-10-2014)“…There is little information on the early kinetics of hepatitis delta virus (HDV) and hepatitis B surface antigen (HBsAg) during interferon-α therapy. Here a…”
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Journal Article -
14
Comparing Pain in Patients Undergoing Percutaneous Versus Transjugular Techniques of Liver Biopsy
Published 01-01-2016“…No study was found in the initial review of the literature comparing pain experienced by patients using the medical technique of Percutaneous Liver Biopsy…”
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Dissertation -
15
Ribavirin improves early responses to peginterferon through enhanced interferon signaling
Published in Gastroenterology (New York, N.Y. 1943) (17-03-2010)Get full text
Journal Article -
16
A functional serotonin transporter gene polymorphism and depressive effects associated with interferon-alpha treatment
Published in Psychosomatics (Washington, D.C.) (01-03-2010)“…Interferon-alpha (IFN-alpha) treatment frequently induces depression, potentially leading to early dose reductions or a shorter duration of treatment, which…”
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Journal Article