Search Results - "Haynes, Chad A."

Rethinking biological activation of methane and conversion to liquid fuels by Haynes, Chad A, Gonzalez, Ramon

“…Methane is an energy resource that is currently being wasted through emissions, venting and flaring during petroleum extraction. Recent discoveries regarding…”
Get full text

Structural basis of biological nitrogen fixation by Rees, Douglas C, Akif Tezcan, F, Haynes, Chad A, Walton, Mika Y, Andrade, Susana, Einsle, Oliver, Howard, James B

“…Biological nitrogen fixation is mediated by the nitrogenase enzyme system that catalyses the ATP dependent reduction of atmospheric dinitrogen to ammonia…”
Get full text

Mechanism-Informed Refinement Reveals Altered Substrate-Binding Mode for Catalytically Competent Nitroreductase by Pitsawong, Warintra, Haynes, Chad A., Koder, Ronald L., Rodgers, David W., Miller, Anne-Frances

“…Nitroreductase (NR) from Enterobacter cloacae reduces diverse nitroaromatics including herbicides, explosives, and prodrugs, and holds promise for…”
Get full text

Turnover-Dependent Inactivation of the Nitrogenase MoFe-Protein at High pH by Yang, Kun-Yun, Haynes, Chad A, Spatzal, Thomas, Rees, Douglas C, Howard, James B

“…Proton uptake accompanies the reduction of all known substrates by nitrogenase. As a consequence, a higher pH should limit the availability of protons as a…”
Get full text

Structures of nitroreductase in three states: effects of inhibitor binding and reduction by Haynes, Chad A, Koder, Ronald L, Miller, Anne-Frances, Rodgers, David W

“…The crystal structure of the nitroreductase enzyme from Enterobacter cloacae has been determined for the oxidized form in separate complexes with benzoate and…”
Get full text

Flavin Thermodynamics Explain the Oxygen Insensitivity of Enteric Nitroreductases by Koder, Ronald L, Haynes, Chad A, Rodgers, Michael E, Rodgers, David W, Miller, Anne-Frances

“…Bacterial nitroreductases are NAD(P)H-dependent flavoenzymes which catalyze the oxygen-insensitive reduction of nitroaromatics, quinones, and riboflavin…”
Get full text

Structures of Nitroreductase in Three States by Haynes, Chad A., Koder, Ronald L., Miller, Anne-Frances, Rodgers, David W.

“…The crystal structure of the nitroreductase enzyme from Enterobacter cloacae has been determined for the oxidized form in separate complexes with benzoate and…”
Get full text