Search Results - "Haylor, J"

Localization of matrix metalloproteinases and their inhibitors in experimental progressive kidney scarring by Ahmed, A.K., Haylor, J.L., El Nahas, A.M., Johnson, T.S.

“…The extracellular matrix (ECM) is in a continual state of turnover with homeostasis maintained by balancing synthesis and degradation rates. During progressive…”
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Feline Chronic Kidney Disease Is Associated With Upregulation of Transglutaminase 2: A Collagen Cross-Linking Enzyme by Sánchez-Lara, A. C., Elliott, J., Syme, H. M., Brown, C. A., Haylor, J. L.

“…Chronic kidney disease is a major cause of morbidity and mortality in cats. Transglutaminase 2 (TG2) is a calcium-dependent enzyme proposed to mediate…”
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Seliciclib inhibits renal hypertrophy but not fibrosis in the rat following subtotal nephrectomy by Nutter, F, Khwaja, A, Haylor, J

“…5/6 subtotal nephrectomy (SNx) is a non-immune stimulus used to induce renal fibrosis. The ability of seliciclib, a cyclin-dependent kinase inhibitor, to…”
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Interference of gadolinium-based contrast agents with the measurement of serum creatinine by the Jaffe reaction by Haylor, J, Vickers, M E, Morcos, S K

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The Effect of Body Temperature in a Rat Model of Renal Ischemia-Reperfusion Injury by Delbridge, M.S, Shrestha, B.M, Raftery, A.T, El Nahas, A.M, Haylor, J.L

“…Abstract Background Renal ischemia-reperfusion injury (IRI) is an unavoidable event in renal transplantation; the effects of IRI can be seen in both the acute…”
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Factors influencing long-term outcomes following renal transplantation: a review by Shrestha, B M, Haylor, J L

“…Despite continuing advances in immunosuppressive and supportive therapies, the success of renal transplantation is impacted by factors present in the donor and…”
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Caspase-3 and apoptosis in experimental chronic renal scarring by Yang, Bin, El Nahas, A. Meguid, Thomas, Graham L., Haylor, John L., Watson, Philip F., Wagner, Bart, Johnson, Timothy S.

“…Caspase-3 and apoptosis in experimental chronic renal scarring. Caspase-3 is a member of the caspase enzyme family, having a central role in the execution of…”
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Inhibition of compensatory renal growth by the N-terminus of a sheep-derived peptide by Haylor, J.L., Parker, E., Risbridger, G.P., Beale, D., Brown, B.L., Dobson, P.R.M., Clarke, I.J., Hart, J.E.

“…The N-terminal sequence of a novel sheep-derived peptide with growth inhibitory activity has been obtained. The N-terminal fragment was chemically synthesised…”
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FTY720 Reduces Extracellular Matrix Expansion Associated With Ischemia-Reperfusion Induced Injury by Delbridge, M.S, Shrestha, B.M, Raftery, A.T, El Nahas, A.M, Haylor, J

“…Abstract Background Ischemia-reperfusion (IR) is one of the strongest nonimmune factors associated with the development of chronic allograft nephropathy (CAN)…”
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Transglutaminase transcription and antigen translocation in experimental renal scarring by JOHNSON, T. S, SKILL, N. J, EL NAHAS, A. M, OLDROYD, S. D, THOMAS, G. L, DOUTHWAITE, J. A, HAYLOR, J. L, GRIFFIN, M

“…It was recently demonstrated that renal tissue transglutaminase (tTg) protein and its catalytic product the epsilon(gamma-glutamyl) lysine protein cross-link…”
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Stem cell factor in a rat model of serum nephrotoxic nephritis by El Kossi, M M, Haylor, J L, Johnson, T S, El Nahas, A M

“…Stem cell factor (SCF) has been implicated in many disease processes characterized by tissue remodelling and fibrosis. The growth factor (SCF) was evaluated in…”
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Bosentan, an orally active endothelin antagonist: effect on the renal response to contrast media by Oldroyd, S D, Haylor, J L, Morcos, S K

“…To examine the effect of bosentan, an orally active endothelin-receptor antagonist, on the renal response to contrast media in the isolated perfused rat kidney…”
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Effects of adenosine receptor antagonists on the responses to contrast media in the isolated rat kidney by Oldroyd, S D, Fang, L, Haylor, J L, Yates, M S, El Nahas, A M, Morcos, S K

“…Contrast media can induce both a decrease in renal blood flow and a reduction in glomerular filtration rate (GFR) when administered to both experimental…”
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Endothelin antagonism and contrast nephropathy by Haylor, John L., Morcos, Sameh K.

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Effect of radiographic contrast media on endothelium derived nitric oxide-dependent renal vasodilatation by Morcos, S K, Oldroyd, S, Haylor, J

“…The effect of diatrizoate (Urografin325) on the cumulative dose-response curve of the vasodilatory response to acetylcholine was studied in the isolated…”
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Expression of apoptosis-related genes and proteins in experimental chronic renal scarring by BIN YANG, JOHNSON, Timothy S, THOMAS, Graham L, WATSON, Philip F, WAGNER, Bart, SKILL, Nicholas J, HAYLOR, John L, EL NAHAS, A. Meguid

“…Apoptosis has been proposed to play an important role in the progression of renal scarring. The mechanisms that determine whether a cell enters the apoptotic…”
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Apoptosis and expression of BCL-2 and BAX in cyclosporine-induced experimental renal fibrosis by Rawat, S, Gray, C, Johnson, T.S, Raftery, A.T, El Nahas, A.M, Haylor, J

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The haemodynamic effects of iodinated water soluble radiographic contrast media: a review by Morcos, S.K, Dawson, P, Pearson, J.D, Jeremy, J.Y, Davenport, A.P, Yates, M.S, Tirone, P, Cipolla, P, de Haën, C, Muschick, P, Krause, W, Refsum, H, Emery, C.J, Liss, Per, Nygren, A, Haylor, J, Pugh, N.D, Karlsson, J.O.G

“…All classes of iodinated water-soluble radiographic contrast media (RCM) are vasoactive with the iso-osmolar dimers inducing the least changes in the vascular…”
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IGF-I inhibitors reduce compensatory hyperfiltration in the isolated rat kidney following unilateral nephrectomy by Haylor, John L., Mckillop, Iain H., Oldroyd, Simon D., El Nahas, Meguid A.

“…Background. A role for insulin-like growth factor-I (IGF-I) as a mediator of renal hyperfiltration and hyperperfusion following unilateral nephrectomy (UNx)…”
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Aspects of contrast media nephrotoxicity by Morcos, S.K., Epstein, F.H., Haylor, J., Dobrota, M.

“…The authors present a wide-ranging overview of our current knowledge and understanding of the problem of contrast agent associated nephrotxicity and its…”
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