Search Results - "Hayley, J"

The Impact of Anisotropic Sky Sampling on the Hubble Constant in Numerical Relativity by Macpherson, Hayley J.

“…We study the impact of nearby inhomogeneities on an observer’s inference of the Hubble constant. Large-scale structures induce a dependence of cosmological…”
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Global Observational Evidence of Strong Linkage Between Dew Point Temperature and Precipitation Extremes by Ali, Haider, Fowler, Hayley J., Mishra, Vimal

“…Using global station‐based observations of precipitation, near‐surface air temperature (SAT), and dew point temperature (DPT), we show that the negative…”
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Real‐Time Flood Forecasting Based on a High‐Performance 2‐D Hydrodynamic Model and Numerical Weather Predictions by Ming, Xiaodong, Liang, Qiuhua, Xia, Xilin, Li, Dingmin, Fowler, Hayley J.

“…A flood forecasting system commonly consists of at least two essential components, that is, a numerical weather prediction (NWP) model to provide rainfall…”
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Local heating of radiation belt electrons to ultra-relativistic energies by Allison, Hayley J., Shprits, Yuri Y.

“…Electrically charged particles are trapped by the Earth’s magnetic field, forming the Van Allen radiation belts. Observations show that electrons in this…”
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Activation of an IL6 Inflammatory Loop Mediates Trastuzumab Resistance in HER2+ Breast Cancer by Expanding the Cancer Stem Cell Population by Korkaya, Hasan, Kim, Gwang-il, Davis, April, Malik, Fayaz, Henry, N. Lynn, Ithimakin, Suthinee, Quraishi, Ahmed A., Tawakkol, Nader, D'Angelo, Rosemarie, Paulson, Amanda K., Chung, Susan, Luther, Tahra, Paholak, Hayley J., Liu, Suling, Hassan, Khaled A., Zen, Qin, Clouthier, Shawn G., Wicha, Max S.

“…Although inactivation of the PTEN gene has been implicated in the development of resistance to the HER2 targeting antibody trastuzumab, the mechanisms…”
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Advances in understanding large‐scale responses of the water cycle to climate change by Allan, Richard P., Barlow, Mathew, Byrne, Michael P., Cherchi, Annalisa, Douville, Hervé, Fowler, Hayley J., Gan, Thian Y., Pendergrass, Angeline G., Rosenfeld, Daniel, Swann, Abigail L. S., Wilcox, Laura J., Zolina, Olga

“…Globally, thermodynamics explains an increase in atmospheric water vapor with warming of around 7%/°C near to the surface. In contrast, global precipitation…”
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Intensification of short-duration rainfall extremes and implications for flood risk: current state of the art and future directions by Fowler, Hayley J, Wasko, Conrad, Prein, Andreas F

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A Comprehensive Comparison of Transmembrane Domains Reveals Organelle-Specific Properties by Sharpe, Hayley J., Stevens, Tim J., Munro, Sean

“…The various membranes of eukaryotic cells differ in composition, but it is at present unclear if this results in differences in physical properties. The…”
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Detection of continental-scale intensification of hourly rainfall extremes by Guerreiro, Selma B., Fowler, Hayley J., Barbero, Renaud, Westra, Seth, Lenderink, Geert, Blenkinsop, Stephen, Lewis, Elizabeth, Li, Xiao-Feng

“…Temperature scaling studies suggest that hourly rainfall magnitudes might increase beyond thermodynamic expectations with global warming 1 – 3 ; that is, above…”
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Performance on the balloon analogue risk task and anticipatory response inhibition task is associated with severity of impulse control behaviours in people with Parkinson’s disease by Hall, Alison, Weightman, Matthew, Jenkinson, Ned, MacDonald, Hayley J.

“…Dopamine agonist medication is one of the largest risk factors for development of problematic impulse control behaviours (ICBs) in people with Parkinson’s…”
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Negative feedback control of neuronal activity by microglia by Badimon, Ana, Strasburger, Hayley J., Ayata, Pinar, Chen, Xinhong, Nair, Aditya, Ikegami, Ako, Hwang, Philip, Chan, Andrew T., Graves, Steven M., Uweru, Joseph O., Ledderose, Carola, Kutlu, Munir Gunes, Wheeler, Michael A., Kahan, Anat, Ishikawa, Masago, Wang, Ying-Chih, Loh, Yong-Hwee E., Jiang, Jean X., Surmeier, D. James, Robson, Simon C., Junger, Wolfgang G., Sebra, Robert, Calipari, Erin S., Kenny, Paul J., Eyo, Ukpong B., Colonna, Marco, Quintana, Francisco J., Wake, Hiroaki, Gradinaru, Viviana, Schaefer, Anne

“…Microglia, the brain’s resident macrophages, help to regulate brain function by removing dying neurons, pruning non-functional synapses, and producing ligands…”
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Systematic longitudinal survey of invasive Escherichia coli in England demonstrates a stable population structure only transiently disturbed by the emergence of ST131 by Kallonen, Teemu, Brodrick, Hayley J, Harris, Simon R, Corander, Jukka, Brown, Nicholas M, Martin, Veronique, Peacock, Sharon J, Parkhill, Julian

“…associated with urinary tract infections and bacteremia has been intensively investigated, including recent work focusing on the virulent, globally…”
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Karakoram temperature and glacial melt driven by regional atmospheric circulation variability by Forsythe, Nathan, Fowler, Hayley J., Li, Xiao-Feng, Blenkinsop, Stephen, Pritchard, David

“…Identifying mechanisms driving spatially heterogeneous glacial mass-balance patterns in the Himalaya, including the ‘Karakoram anomaly’, is crucial for…”
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Modular Organization and Assembly of SWI/SNF Family Chromatin Remodeling Complexes by Mashtalir, Nazar, D’Avino, Andrew R., Michel, Brittany C., Luo, Jie, Pan, Joshua, Otto, Jordan E., Zullow, Hayley J., McKenzie, Zachary M., Kubiak, Rachel L., St. Pierre, Roodolph, Valencia, Alfredo M., Poynter, Steven J., Cassel, Seth H., Ranish, Jeffrey A., Kadoch, Cigall

“…Mammalian SWI/SNF (mSWI/SNF) ATP-dependent chromatin remodeling complexes are multi-subunit molecular machines that play vital roles in regulating genomic…”
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Long working hours, sedentary work, noise, night shifts and risk of ischaemic heart disease by Eng, Amanda, Denison, Hayley J, Corbin, Marine, Barnes, Lucy, 't Mannetje, Andrea, McLean, Dave, Jackson, Rod, Laird, Ian, Douwes, Jeroen

“…Ischaemic heart disease (IHD) is a leading cause of death in Western countries. The aim of this study was to examine the associations between occupational…”
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Genomic Analysis of Smoothened Inhibitor Resistance in Basal Cell Carcinoma by Sharpe, Hayley J., Pau, Gregoire, Dijkgraaf, Gerrit J., Basset-Seguin, Nicole, Modrusan, Zora, Januario, Thomas, Tsui, Vickie, Durham, Alison B., Dlugosz, Andrzej A., Haverty, Peter M., Bourgon, Richard, Tang, Jean Y., Sarin, Kavita Y., Dirix, Luc, Fisher, David C., Rudin, Charles M., Sofen, Howard, Migden, Michael R., Yauch, Robert L., de Sauvage, Frederic J.

“…Smoothened (SMO) inhibitors are under clinical investigation for the treatment of several cancers. Vismodegib is approved for the treatment of locally advanced…”
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Exploring stop signal reaction time over two sessions of the anticipatory response inhibition task by Hall, Alison, Jenkinson, Ned, MacDonald, Hayley J.

“…Various behavioural tasks measure response inhibition encompassing the ability to cancel unwanted actions, evaluated via stop signal reaction time (SSRT). It…”
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Epigenetic regulation of brain region-specific microglia clearance activity by Ayata, Pinar, Badimon, Ana, Strasburger, Hayley J., Duff, Mary Kaye, Montgomery, Sarah E., Loh, Yong-Hwee E., Ebert, Anja, Pimenova, Anna A., Ramirez, Brianna R., Chan, Andrew T., Sullivan, Josefa M., Purushothaman, Immanuel, Scarpa, Joseph R., Goate, Alison M., Busslinger, Meinrad, Shen, Li, Losic, Bojan, Schaefer, Anne

“…The rapid elimination of dying neurons and nonfunctional synapses in the brain is carried out by microglia, the resident myeloid cells of the brain. Here we…”
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Taming the Triskelion: Bacterial Manipulation of Clathrin by Latomanski, Eleanor A, Newton, Hayley J

“…The entry of pathogens into nonphagocytic host cells has received much attention in the past three decades, revealing a vast array of strategies employed by…”
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Quality‐control of an hourly rainfall dataset and climatology of extremes for the UK by Blenkinsop, Stephen, Lewis, Elizabeth, Chan, Steven C., Fowler, Hayley J.

“…ABSTRACT Sub‐daily rainfall extremes may be associated with flash flooding, particularly in urban areas but, compared with extremes on daily timescales, have…”
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