Search Results - "Haykir, Betul"
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The Ip6k1 and Ip6k2 Kinases Are Critical for Normal Renal Tubular Function
Published in Journal of the American Society of Nephrology (01-04-2024)“…Kidneys are gatekeepers of systemic inorganic phosphate balance because they control urinary phosphate excretion. In yeast and plants, inositol…”
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2
The calcium-sensing receptor has only a parathyroid hormone-dependent role in the acute response of renal phosphate transporters to phosphate intake
Published in American journal of physiology. Renal physiology (01-05-2024)“…The kidney controls systemic inorganic phosphate (Pi) levels by adapting reabsorption to Pi intake. Renal Pi reabsorption is mostly mediated by…”
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3
A novel mouse model for familial hypocalciuric hypercalcemia (FHH1) reveals PTH-dependent and independent CaSR defects
Published in Pflügers Archiv (01-05-2024)“…The Calcium-sensing receptor (CaSR) senses extracellular calcium, regulates parathyroid hormone (PTH) secretion, and has additional functions in various organs…”
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4
Acute adaptation of renal phosphate transporters in the murine kidney to oral phosphate intake requires multiple signals
Published in Acta Physiologica (01-06-2022)“…Aims Dietary inorganic phosphate (Pi) modulates renal Pi reabsorption by regulating the expression of the NaPi‐IIa and NaPi‐IIc Pi transporters. Here, we aimed…”
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5
Nradd Acts as a Negative Feedback Regulator of Wnt/β-Catenin Signaling and Promotes Apoptosis
Published in Biomolecules (Basel, Switzerland) (01-01-2021)“…Wnt/β-catenin signaling controls many biological processes for the generation and sustainability of proper tissue size, organization and function during…”
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6
Fibroblast growth factor 23 leads to endolysosomal routing of the renal phosphate cotransporters NaPi-IIa and NaPi-IIc in vivo
Published in American journal of physiology. Renal physiology (01-12-2021)“…Na -dependent phosphate cotransporters NaPi-IIa and NaPi-IIc, located at the brush-border membrane of renal proximal tubules, are regulated by numerous…”
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7
Expression of NaPi-IIb in rodent and human kidney and upregulation in a model of chronic kidney disease
Published in Pflügers Archiv (01-04-2020)“…Na + -coupled phosphate cotransporters from the SLC34 and SLC20 families of solute carriers mediate transepithelial transport of inorganic phosphate (Pi)…”
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8
Inositol hexakisphosphate kinases 1 and 2 (IP6K1/2) are involved in renal control of phosphate homeostasis
Published in The FASEB journal (01-05-2021)“…Phosphate (Pi) is an indispensable component of living organisms. In the body, Pi homeostasis is tightly regulated by four main tissues: intestine, kidney,…”
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9
Expression of phosphate and calcium transporters and their regulators in parotid glands of mice
Published in Pflügers Archiv (01-02-2023)“…The concentration of inorganic phosphate (Pi) in plasma is under hormonal control, with deviations from normal values promptly corrected to avoid hyper- or…”
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Journal Article -
10
Ölüm Reseptörü ġle WNT/β-Katenġn Sġnyal Yolaği Arasindakġ Ġlġġkġnġn Zebrabaliği Modelġnde Araġtirilmasi
Published 01-01-2017“…Wnt/B-katenin sinyal İletim yolağı, embriyonik gelişim sırasında hüce bölünmesinde, hücre kaderinin belirlenmesinde, doku homeostazisinin sürekliliğinde ve…”
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Dissertation