Search Results - "Hayes, John"

Oxidative Stress in Cancer by Hayes, John D., Dinkova-Kostova, Albena T., Tew, Kenneth D.

“…Contingent upon concentration, reactive oxygen species (ROS) influence cancer evolution in apparently contradictory ways, either initiating/stimulating…”
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Modeling and Remodeling Writing by Hayes, John R.

“…In Section 1 of this article, the author discusses the succession of models of adult writing that he and his colleagues have proposed from 1980 to the present…”
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The Promise and Challenge of Stochastic Computing by Alaghi, Armin, Qian, Weikang, Hayes, John P.

“…Stochastic computing (SC) is an unconventional method of computation that treats data as probabilities. Typically, each bit of an <inline-formula> <tex-math…”
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The Nrf2 regulatory network provides an interface between redox and intermediary metabolism by Hayes, John D., Dinkova-Kostova, Albena T.

“…•Nrf2 is part of a complex regulatory network that responds to environmental cues.•Nrf2 allows adaptation by inducing cytoprotective genes and maintaining…”
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NRF2 and KEAP1 mutations: permanent activation of an adaptive response in cancer by Hayes, John D., McMahon, Michael

“…Transcription factor nuclear factor-erythroid 2-related factor 2 (NRF2) controls cellular adaptation to oxidants and electrophiles by inducing antioxidant and…”
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The Keap1/Nrf2 pathway in health and disease: from the bench to the clinic by O'Connell, Maria A, Hayes, John D

“…The transcription factor nuclear factor-erythroid 2 p45-related factor 2 (Nrf2, with gene called NFE2L2) is a master regulator of the antioxidant response. In…”
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A partnership with the proteasome; the destructive nature of GSK3 by Robertson, Holly, Hayes, John D., Sutherland, Calum

“…[Display omitted] Glycogen Synthase Kinase-3 (GSK3) was originally reported as a key enzyme of glucose homeostasis through regulation of the rate of glycogen…”
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Dual regulation of transcription factor Nrf2 by Keap1 and by the combined actions of β-TrCP and GSK-3 by Hayes, John D, Chowdhry, Sudhir, Dinkova-Kostova, Albena T, Sutherland, Calum

“…Nuclear factor-erythroid 2 p45 (NF-E2 p45)-related factor 2 (Nrf2) is a master regulator of redox homoeostasis that allows cells to adapt to oxidative stress…”
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Therapeutic targeting of the NRF2 and KEAP1 partnership in chronic diseases by Cuadrado, Antonio, Rojo, Ana I., Wells, Geoffrey, Hayes, John D., Cousin, Sharon P., Rumsey, William L., Attucks, Otis C., Franklin, Stephen, Levonen, Anna-Liisa, Kensler, Thomas W., Dinkova-Kostova, Albena T.

“…The transcription factor NF-E2 p45-related factor 2 (NRF2; encoded by NFE2L2 ) and its principal negative regulator, the E3 ligase adaptor Kelch-like…”
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Fat, protein, and temperature each contribute to reductions in capsaicin oral burn by Gaiser, Justin, Hayes, John E.

“…It is widely accepted that milk provides the greatest relief from capsaicin burn, an effect typically attributed to its fat content and temperature…”
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Correlation or Causality between Land Cover Patterns and the Urban Heat Island Effect? Evidence from Brisbane, Australia by Deilami, Kaveh, Kamruzzaman, Md, Hayes, John Francis

“…Numerous studies have identified associations between the surface urban heat island (SUHI) effect (i.e., SUHI, hereinafter is referred to as UHI) and urban…”
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Mechanisms of activation of the transcription factor Nrf2 by redox stressors, nutrient cues, and energy status and the pathways through which it attenuates degenerative disease by Tebay, Lauren E., Robertson, Holly, Durant, Stephen T., Vitale, Steven R., Penning, Trevor M., Dinkova-Kostova, Albena T., Hayes, John D.

“…Nuclear factor-erythroid 2 p45-related factor 2 (Nrf2) regulates the basal and stress-inducible expression of a battery of genes encoding key components of the…”
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Hollow core optical fibres with comparable attenuation to silica fibres between 600 and 1100 nm by Sakr, Hesham, Chen, Yong, Jasion, Gregory T., Bradley, Thomas D., Hayes, John R., Mulvad, Hans Christian H., Davidson, Ian A., Numkam Fokoua, Eric, Poletti, Francesco

“…For over 50 years, pure or doped silica glass optical fibres have been an unrivalled platform for the transmission of laser light and optical data at…”
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SCF/β-TrCP Promotes Glycogen Synthase Kinase 3-Dependent Degradation of the Nrf2 Transcription Factor in a Keap1-Independent Manner by Rada, Patricia, Rojo, Ana I., Chowdhry, Sudhir, McMahon, Michael, Hayes, John D., Cuadrado, Antonio

“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Quantifying Sweet Taste Liker Phenotypes: Time for Some Consistency in the Classification Criteria by Iatridi, Vasiliki, Hayes, John E, Yeomans, Martin R

“…Taste hedonics is a well-documented driver of food consumption. The role of sweetness in directing ingestive behavior is largely rooted in biology. One can…”
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Transcription factor Nrf1 is topologically repartitioned across membranes to enable target gene transactivation through its acidic glucose-responsive domains by Zhang, Yiguo, Ren, Yonggang, Li, Shaojun, Hayes, John D

“…The membrane-bound Nrf1 transcription factor regulates critical homeostatic and developmental genes. The conserved N-terminal homology box 1 (NHB1) sequence in…”
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Introduction to Debate Two: Should the AAG Consider Carbon Offsets as Part of Its Transition to Low-Emissions Annual Meetings? by Hayes, John T.

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Structural and Functional Characterization of Nrf2 Degradation by the Glycogen Synthase Kinase 3/β-TrCP Axis by Rada, Patricia, Rojo, Ana I., Evrard-Todeschi, Nathalie, Innamorato, Nadia G., Cotte, Axelle, Jaworski, Tomasz, Tobón-Velasco, Julio C., Devijver, Herman, García-Mayoral, María Flor, Van Leuven, Fred, Hayes, John D., Bertho, Gildas, Cuadrado, Antonio

“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Physical Approaches to Masking Bitter Taste: Lessons from Food and Pharmaceuticals by Coupland, John N., Hayes, John E.

“…Many drugs and desirable phytochemicals are bitter, and bitter tastes are aversive. Food and pharmaceutical manufacturers share a common need for…”
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p62/SQSTM1 Is a Target Gene for Transcription Factor NRF2 and Creates a Positive Feedback Loop by Inducing Antioxidant Response Element-driven Gene Transcription by Jain, Ashish, Lamark, Trond, Sjøttem, Eva, Bowitz Larsen, Kenneth, Atesoh Awuh, Jane, Øvervatn, Aud, McMahon, Michael, Hayes, John D., Johansen, Terje

“…The p62/SQSTM1 (sequestosome 1) protein, which acts as a cargo receptor for autophagic degradation of ubiquitinated targets, is up-regulated by various…”
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