Search Results - "Hayes, Jay"
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Characterization and modeling of the Haemophilus influenzae core and supragenomes based on the complete genomic sequences of Rd and 12 clinical nontypeable strains
Published in Genome biology (05-06-2007)“…The distributed genome hypothesis (DGH) posits that chronic bacterial pathogens utilize polyclonal infection and reassortment of genic characters to ensure…”
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Comparative Genomic Analyses of Seventeen Streptococcus pneumoniae Strains: Insights into the Pneumococcal Supragenome
Published in Journal of Bacteriology (01-11-2007)“…Article Usage Stats Services JB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Strain-specific virulence phenotypes of Streptococcus pneumoniae assessed using the Chinchilla laniger model of otitis media
Published in PloS one (09-04-2008)“…Streptococcus pneumoniae [Sp] infection is associated with local and systemic disease. Our current understanding of the differential contributions of genetic…”
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Mucosal Biofilm Formation on Middle-Ear Mucosa in the Chinchilla Model of Otitis Media
Published in JAMA : the journal of the American Medical Association (03-04-2002)“…CONTEXT Chronic otitis media with effusion (OME) has long been considered to be a sterile inflammatory process. The previous application of molecular…”
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Comparative supragenomic analyses among the pathogens Staphylococcus aureus, Streptococcus pneumoniae, and Haemophilus influenzae using a modification of the finite supragenome model
Published in BMC genomics (13-04-2011)“…Staphylococcus aureus is associated with a spectrum of symbiotic relationships with its human host from carriage to sepsis and is frequently associated with…”
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Extensive Genomic Plasticity in Pseudomonas aeruginosa Revealed by Identification and Distribution Studies of Novel Genes among Clinical Isolates
Published in Infection and Immunity (01-09-2006)“…The distributed genome hypothesis (DGH) states that each strain within a bacterial species receives a unique distribution of genes from a population-based…”
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Virulence phenotypes of low-passage clinical isolates of nontypeable Haemophilus influenzae assessed using the chinchilla laniger model of otitis media
Published in BMC microbiology (14-06-2007)“…The nontypeable Haemophilus influenzae (NTHi) are associated with a spectrum of respiratory mucosal infections including: acute otitis media (AOM); chronic…”
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Identification, Distribution, and Expression of Novel Genes in 10 Clinical Isolates of Nontypeable Haemophilus influenzae
Published in Infection and Immunity (01-06-2005)“…We hypothesize that Haemophilus influenzae, as a species, possesses a much greater number of genes than that found in any single H. influenzae genome. This…”
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Characterization, Distribution, and Expression of Novel Genes among Eight Clinical Isolates of Streptococcus pneumoniae
Published in Infection and Immunity (2006)“…Eightlow-passage-number Streptococcus pneumoniae clinical isolates,each of a different serotype and a different multilocus sequence type,were obtained from…”
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Construction and characterization of a highly redundant Pseudomonas aeruginosa genomic library prepared from 12 clinical isolates: Application to studies of gene distribution among populations
Published in International journal of pediatric otorhinolaryngology (01-11-2006)“…To create, array, and characterize a pooled, high-coverage, genomic library composed of multiple biofilm-forming clinical strains of the opportunistic…”
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Direct Detection of Bacterial Biofilms on the Middle-Ear Mucosa of Children With Chronic Otitis Media
Published in JAMA : the journal of the American Medical Association (12-07-2006)“…CONTEXT Chronic otitis media (OM) is a common pediatric infectious disease. Previous studies demonstrating that metabolically active bacteria exist in…”
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Mucosal Biofilm Formation on Middle-Ear Mucosa in a Nonhuman Primate Model of Chronic Suppurative Otitis Media
Published in The Laryngoscope (01-08-2005)“…Background: An increased awareness of bacterial biofilms and their formation has led to a better understanding of bacterial infections that occur in the middle…”
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Partial Characterization of Normal and Haemophilus Influenzae—Infected Mucosal Complementary DNA Libraries in Chinchilla Middle Ear Mucosa
Published in Annals of otology, rhinology & laryngology (01-04-2010)“…Objectives: We sought to construct and partially characterize complementary DNA (cDNA) libraries prepared from the middle ear mucosa (MEM) of chinchillas to…”
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Amino acids in the beta-amyloid precursor protein YENP motif modulate endocytosis and cellular distribution
Published in Neurobiology of aging (01-05-2000)Get full text
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Characterization, Distribution, and Expression of Novel Genes among Eight Clinical Isolates of Streptococcuspneumoniae
Published in Infection and immunity (01-01-2006)“…ABSTRACT Eight low-passage-number Streptococcus pneumoniae clinical isolates, each of a different serotype and a different multilocus sequence type, were…”
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Development and characterization of a pooled Haemophilus influenzae genomic library for the evaluation of gene expression changes associated with mucosal biofilm formation in otitis media
Published in International journal of pediatric otorhinolaryngology (01-07-2003)“…Haemophilus influenzae is one of the most important respiratory pathogens of man. It has been etiologically associated with otitis media, otorrhea, and chronic…”
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Mutagenesis Identifies New Signals for β-Amyloid Precursor Protein Endocytosis, Turnover, and the Generation of Secreted Fragments, Including Aβ42
Published in The Journal of biological chemistry (02-07-1999)“…It has long been assumed that the C-terminal motif, NP X Y, is the internalization signal for β-amyloid precursor protein (APP) and that the NP X Y tyrosine…”
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Chemical Relationships in Waters and Sediments of Some Urban Streams, With Particular Reference to Heavy Metals and Phosphorus
Published 01-01-1996“…This thesis describes two studies of the chemistry of freshwater streams in the Sydney basin.The first was a survey of 86 waterways, sampled under low flow…”
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Dissertation