Search Results - "Hayes, Ben J."

Simultaneous discovery, estimation and prediction analysis of complex traits using a bayesian mixture model by Moser, Gerhard, Lee, Sang Hong, Hayes, Ben J, Goddard, Michael E, Wray, Naomi R, Visscher, Peter M

“…Gene discovery, estimation of heritability captured by SNP arrays, inference on genetic architecture and prediction analyses of complex traits are usually…”
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The future of livestock breeding: genomic selection for efficiency, reduced emissions intensity, and adaptation by Hayes, Ben J, Lewin, Harris A, Goddard, Michael E

“…As the global population and global wealth both continue to increase, so will the demand for livestock products, especially those that are highly nutritious…”
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Pitfalls of predicting complex traits from SNPs by Wray, Naomi R., Yang, Jian, Hayes, Ben J., Price, Alkes L., Goddard, Michael E., Visscher, Peter M.

“…The data from genome-wide association studies can be applied to genotype data to predict the phenotype of a complex trait. Here the authors discuss the…”
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A multi-trait, meta-analysis for detecting pleiotropic polymorphisms for stature, fatness and reproduction in beef cattle by Bolormaa, Sunduimijid, Pryce, Jennie E, Reverter, Antonio, Zhang, Yuandan, Barendse, William, Kemper, Kathryn, Tier, Bruce, Savin, Keith, Hayes, Ben J, Goddard, Michael E

“…Polymorphisms that affect complex traits or quantitative trait loci (QTL) often affect multiple traits. We describe two novel methods (1) for finding single…”
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Accuracy of genomic breeding values in multi-breed dairy cattle populations by Hayes, Ben J, Bowman, Phillip J, Chamberlain, Amanda C, Verbyla, Klara, Goddard, Mike E

“…Two key findings from genomic selection experiments are 1) the reference population used must be very large to subsequently predict accurate genomic estimated…”
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Genetic architecture of complex traits and accuracy of genomic prediction: coat colour, milk-fat percentage, and type in Holstein cattle as contrasting model traits by Hayes, Ben J, Pryce, Jennie, Chamberlain, Amanda J, Bowman, Phil J, Goddard, Mike E

“…Prediction of genetic merit using dense SNP genotypes can be used for estimation of breeding values for selection of livestock, crops, and forage species; for…”
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Metagenomic Predictions: A Review 10 years on by Ross, Elizabeth M, Hayes, Ben J

“…Metagenomic predictions use variation in the metagenome (microbiome profile) to predict the unknown phenotype of the associated host. Metagenomic predictions…”
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Selection on Optimal Haploid Value Increases Genetic Gain and Preserves More Genetic Diversity Relative to Genomic Selection by Daetwyler, Hans D, Hayden, Matthew J, Spangenberg, German C, Hayes, Ben J

“…Doubled haploids are routinely created and phenotypically selected in plant breeding programs to accelerate the breeding cycle. Genomic selection, which makes…”
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Genetic influence on within-person longitudinal change in anthropometric traits in the UK Biobank by Kemper, Kathryn E., Sidorenko, Julia, Wang, Huanwei, Hayes, Ben J., Wray, Naomi R., Yengo, Loic, Keller, Matthew C., Goddard, Michael, Visscher, Peter M.

“…The causes of temporal fluctuations in adult traits are poorly understood. Here, we investigate the genetic determinants of within-person trait variability of…”
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Polymorphic regions affecting human height also control stature in cattle by Pryce, Jennie E, Hayes, Ben J, Bolormaa, Sunduimijid, Goddard, Michael E

“…Orthologous positions of 55 genes associated with height in four human populations were located on the bovine genome. Single nucleotide polymorphisms close to…”
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A catalogue of novel bovine long noncoding RNA across 18 tissues by Koufariotis, Lambros T, Chen, Yi-Ping Phoebe, Chamberlain, Amanda, Vander Jagt, Christy, Hayes, Ben J

“…Long non-coding RNA (lncRNA) have been implicated in diverse biological roles including gene regulation and genomic imprinting. Identifying lncRNA in bovine…”
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Mitigation of inbreeding while preserving genetic gain in genomic breeding programs for outbred plants by Lin, Zibei, Shi, Fan, Hayes, Ben J., Daetwyler, Hans D.

“…Key message Heuristic genomic inbreeding controls reduce inbreeding in genomic breeding schemes without reducing genetic gain . Genomic selection is…”
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Multi-breed genomic evaluation for tropical beef cattle when no pedigree information is available by Hayes, Ben J, Copley, James, Dodd, Elsie, Ross, Elizabeth M, Speight, Shannon, Fordyce, Geoffry

“…Abstract Background It has been challenging to implement genomic selection in multi-breed tropical beef cattle populations. If commercial (often crossbred)…”
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A dense SNP-based linkage map for Atlantic salmon (Salmo salar) reveals extended chromosome homeologies and striking differences in sex-specific recombination patterns by Lien, Sigbjørn, Gidskehaug, Lars, Moen, Thomas, Hayes, Ben J, Berg, Paul R, Davidson, William S, Omholt, Stig W, Kent, Matthew P

“…The Atlantic salmon genome is in the process of returning to a diploid state after undergoing a whole genome duplication (WGD) event between 25 and100 million…”
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Genomic prediction using low-coverage portable Nanopore sequencing by Lamb, Harrison J, Hayes, Ben J, Randhawa, Imtiaz A S, Nguyen, Loan T, Ross, Elizabeth M

“…Most traits in livestock, crops and humans are polygenic, that is, a large number of loci contribute to genetic variation. Effects at these loci lie along a…”
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Application of infrared thermal technology to assess the level of heat stress and milk yield reduction of cows in tropical smallholder dairy farms by Bang, Nguyen N., Gaughan, John B., Hayes, Ben J., Lyons, Russell E., McNeill, David M.

“…Panting score (PS) is a common research tool used to assess the physiological state of cows exposed to heat stress, but it is subjective. Infrared temperature…”
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Genomic selection and genetic gain for nut yield in an Australian macadamia breeding population by O'Connor, Katie M, Hayes, Ben J, Hardner, Craig M, Alam, Mobashwer, Henry, Robert J, Topp, Bruce L

“…Improving yield prediction and selection efficiency is critical for tree breeding. This is vital for macadamia trees with the time from crossing to production…”
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Expression network analysis of bovine skin infested with Rhipicephalus australis identifies pro-inflammatory genes contributing to tick susceptibility by Mantilla Valdivieso, Emily F., Ross, Elizabeth M., Raza, Ali, Nguyen, Loan, Hayes, Ben J., Jonsson, Nicholas N., James, Peter, Tabor, Ala E.

“…The skin is the primary feeding site of ticks that infest livestock animals such as cattle. The highly specialised functions of skin at the molecular level may…”
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Metagenomic predictions: from microbiome to complex health and environmental phenotypes in humans and cattle by Ross, Elizabeth M, Moate, Peter J, Marett, Leah C, Cocks, Ben G, Hayes, Ben J

“…Mammals have a large cohort of endo- and ecto- symbiotic microorganisms (the microbiome) that potentially influence host phenotypes. There have been numerous…”
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Recent human effective population size estimated from linkage disequilibrium by Tenesa, Albert, Navarro, Pau, Hayes, Ben J, Duffy, David L, Clarke, Geraldine M, Goddard, Mike E, Visscher, Peter M

“…Effective population size (N(e)) determines the amount of genetic variation, genetic drift, and linkage disequilibrium (LD) in populations. Here, we present…”
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