Search Results - "Hayes, Ben J"
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Simultaneous discovery, estimation and prediction analysis of complex traits using a bayesian mixture model
Published in PLoS genetics (01-04-2015)“…Gene discovery, estimation of heritability captured by SNP arrays, inference on genetic architecture and prediction analyses of complex traits are usually…”
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The future of livestock breeding: genomic selection for efficiency, reduced emissions intensity, and adaptation
Published in Trends in genetics (01-04-2013)“…As the global population and global wealth both continue to increase, so will the demand for livestock products, especially those that are highly nutritious…”
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Pitfalls of predicting complex traits from SNPs
Published in Nature reviews. Genetics (01-07-2013)“…The data from genome-wide association studies can be applied to genotype data to predict the phenotype of a complex trait. Here the authors discuss the…”
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A multi-trait, meta-analysis for detecting pleiotropic polymorphisms for stature, fatness and reproduction in beef cattle
Published in PLoS genetics (01-03-2014)“…Polymorphisms that affect complex traits or quantitative trait loci (QTL) often affect multiple traits. We describe two novel methods (1) for finding single…”
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Accuracy of genomic breeding values in multi-breed dairy cattle populations
Published in Genetics selection evolution (Paris) (24-11-2009)“…Two key findings from genomic selection experiments are 1) the reference population used must be very large to subsequently predict accurate genomic estimated…”
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Genetic architecture of complex traits and accuracy of genomic prediction: coat colour, milk-fat percentage, and type in Holstein cattle as contrasting model traits
Published in PLoS genetics (01-09-2010)“…Prediction of genetic merit using dense SNP genotypes can be used for estimation of breeding values for selection of livestock, crops, and forage species; for…”
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Metagenomic Predictions: A Review 10 years on
Published in Frontiers in genetics (20-07-2022)“…Metagenomic predictions use variation in the metagenome (microbiome profile) to predict the unknown phenotype of the associated host. Metagenomic predictions…”
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Selection on Optimal Haploid Value Increases Genetic Gain and Preserves More Genetic Diversity Relative to Genomic Selection
Published in Genetics (Austin) (01-08-2015)“…Doubled haploids are routinely created and phenotypically selected in plant breeding programs to accelerate the breeding cycle. Genomic selection, which makes…”
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Genetic influence on within-person longitudinal change in anthropometric traits in the UK Biobank
Published in Nature communications (06-05-2024)“…The causes of temporal fluctuations in adult traits are poorly understood. Here, we investigate the genetic determinants of within-person trait variability of…”
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Polymorphic regions affecting human height also control stature in cattle
Published in Genetics (Austin) (01-03-2011)“…Orthologous positions of 55 genes associated with height in four human populations were located on the bovine genome. Single nucleotide polymorphisms close to…”
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A catalogue of novel bovine long noncoding RNA across 18 tissues
Published in PloS one (23-10-2015)“…Long non-coding RNA (lncRNA) have been implicated in diverse biological roles including gene regulation and genomic imprinting. Identifying lncRNA in bovine…”
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Mitigation of inbreeding while preserving genetic gain in genomic breeding programs for outbred plants
Published in Theoretical and applied genetics (01-05-2017)“…Key message Heuristic genomic inbreeding controls reduce inbreeding in genomic breeding schemes without reducing genetic gain . Genomic selection is…”
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Multi-breed genomic evaluation for tropical beef cattle when no pedigree information is available
Published in Genetics selection evolution (Paris) (16-10-2023)“…Abstract Background It has been challenging to implement genomic selection in multi-breed tropical beef cattle populations. If commercial (often crossbred)…”
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A dense SNP-based linkage map for Atlantic salmon (Salmo salar) reveals extended chromosome homeologies and striking differences in sex-specific recombination patterns
Published in BMC genomics (19-12-2011)“…The Atlantic salmon genome is in the process of returning to a diploid state after undergoing a whole genome duplication (WGD) event between 25 and100 million…”
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Genomic prediction using low-coverage portable Nanopore sequencing
Published in PloS one (15-12-2021)“…Most traits in livestock, crops and humans are polygenic, that is, a large number of loci contribute to genetic variation. Effects at these loci lie along a…”
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Application of infrared thermal technology to assess the level of heat stress and milk yield reduction of cows in tropical smallholder dairy farms
Published in Journal of dairy science (01-10-2022)“…Panting score (PS) is a common research tool used to assess the physiological state of cows exposed to heat stress, but it is subjective. Infrared temperature…”
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Genomic selection and genetic gain for nut yield in an Australian macadamia breeding population
Published in BMC genomics (20-05-2021)“…Improving yield prediction and selection efficiency is critical for tree breeding. This is vital for macadamia trees with the time from crossing to production…”
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Expression network analysis of bovine skin infested with Rhipicephalus australis identifies pro-inflammatory genes contributing to tick susceptibility
Published in Scientific reports (23-02-2024)“…The skin is the primary feeding site of ticks that infest livestock animals such as cattle. The highly specialised functions of skin at the molecular level may…”
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Metagenomic predictions: from microbiome to complex health and environmental phenotypes in humans and cattle
Published in PloS one (04-09-2013)“…Mammals have a large cohort of endo- and ecto- symbiotic microorganisms (the microbiome) that potentially influence host phenotypes. There have been numerous…”
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Recent human effective population size estimated from linkage disequilibrium
Published in Genome Research (01-04-2007)“…Effective population size (N(e)) determines the amount of genetic variation, genetic drift, and linkage disequilibrium (LD) in populations. Here, we present…”
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