Search Results - "Hayes, Alicia"
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Computationally driven, quantitative experiments discover genes required for mitochondrial biogenesis
Published in PLoS genetics (01-03-2009)“…Mitochondria are central to many cellular processes including respiration, ion homeostasis, and apoptosis. Using computational predictions combined with…”
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Journal Article -
2
Endocardial Endothelial Dysfunction Progressively Disrupts Initially Anti then Pro-Thrombotic Pathways in Heart Failure Mice
Published in PloS one (13-11-2015)“…An experimental model of endocardial thrombosis has not been developed and endocardial endothelial dysfunction in heart failure (HF) is understudied. We sought…”
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Journal Article -
3
Intra-prostatic tumour evolution, steps in metastatic spread and histogenomic associations revealed by integration of multi-region whole-genome sequencing with histopathological features
Published in Genome medicine (19-02-2024)“…Extension of prostate cancer beyond the primary site by local invasion or nodal metastasis is associated with poor prognosis. Despite significant research on…”
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Journal Article -
4
A new system for comparative functional genomics of Saccharomyces yeasts
Published in Genetics (Austin) (01-09-2013)“…Whole-genome sequencing, particularly in fungi, has progressed at a tremendous rate. More difficult, however, is experimental testing of the inferences about…”
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Journal Article -
5
Reciprocal regulation of nuclear import of the yeast MutSα DNA mismatch repair proteins Msh2 and Msh6
Published in DNA repair (04-06-2009)“…DNA mismatch recognition is performed in eukaryotes by two heterodimers known as MutSα (Msh2/Msh6) and MutSβ (Msh2/Msh3) that must reside in the nucleus to…”
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Journal Article -
6
A Systematic Review of Prostate Cancer Heterogeneity: Understanding the Clonal Ancestry of Multifocal Disease
Published in European urology oncology (01-06-2021)“…Studies characterising genomic changes in prostate cancer (PCa) during natural progression have greatly increased our understanding of the disease. A better…”
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Journal Article -
7
Reciprocal regulation of nuclear import of the yeast MutSalpha DNA mismatch repair proteins Msh2 and Msh6
Published in DNA repair (04-06-2009)“…DNA mismatch recognition is performed in eukaryotes by two heterodimers known as MutSalpha (Msh2/Msh6) and MutSbeta (Msh2/Msh3) that must reside in the nucleus…”
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Journal Article -
8
Computationally Driven, Quantitative Experiments Discover Genes Required for Mitochondrial Biogenesis: e1000407
Published in PLoS genetics (01-03-2009)“…Mitochondria are central to many cellular processes including respiration, ion homeostasis, and apoptosis. Using computational predictions combined with…”
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Journal Article -
9
The Army Spouse: Perceptions of Educational Needs during Deployment and Nondeployment Cycles
Published 2011“…The purpose of this study was to identify and compare educational needs and goals during deployment and nondeployment of spouses of active-duty Army service…”
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Dissertation