Search Results - "Hayball, John D."

A Practical Guide to Prepare and Synthetically Modify Graphene Quantum Dots by Sweetman, Martin J., Hickey, Shane M., Brooks, Doug A., Hayball, John D., Plush, Sally E.

“…Due to the favorable properties of graphene quantum dots (GQDs), there has been a rapid development of sensors, devices, and composite materials, which…”
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Therapeutic targeting of HMGB1 during experimental sepsis modulates the inflammatory cytokine profile to one associated with improved clinical outcomes by Stevens, Natalie E., Chapman, Marianne J., Fraser, Cara K., Kuchel, Tim R., Hayball, John D., Diener, Kerrilyn R.

“…Sepsis remains a significant health burden and a major clinical need exists for therapeutics to dampen the excessive and uncontrolled immune activation…”
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A vaccinia-based single vector construct multi-pathogen vaccine protects against both Zika and chikungunya viruses by Prow, Natalie A., Liu, Liang, Nakayama, Eri, Cooper, Tamara H., Yan, Kexin, Eldi, Preethi, Hazlewood, Jessamine E., Tang, Bing, Le, Thuy T., Setoh, Yin Xiang, Khromykh, Alexander A, Hobson-Peters, Jody, Diener, Kerrilyn R., Howley, Paul M., Hayball, John D., Suhrbier, Andreas

“…Zika and chikungunya viruses have caused major epidemics and are transmitted by Aedes aegypti and/or Aedes albopictu s mosquitoes. The “Sementis Copenhagen…”
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Injection site vaccinology of a recombinant vaccinia-based vector reveals diverse innate immune signatures by Hazlewood, Jessamine E, Dumenil, Troy, Le, Thuy T, Slonchak, Andrii, Kazakoff, Stephen H, Patch, Ann-Marie, Gray, Lesley-Ann, Howley, Paul M, Liu, Liang, Hayball, John D, Yan, Kexin, Rawle, Daniel J, Prow, Natalie A, Suhrbier, Andreas

“…Poxvirus systems have been extensively used as vaccine vectors. Herein a RNA-Seq analysis of intramuscular injection sites provided detailed insights into host…”
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Poxvirus-based vector systems and the potential for multi-valent and multi-pathogen vaccines by Natalie A. Prow, Rocio Jimenez Martinez, John D. Hayball, Paul M. Howley, Andreas Suhrbier

“…Introduction: With the increasing number of vaccines and vaccine-preventable diseases, the pressure to generate multi-valent and multi-pathogen vaccines grows…”
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Uterine B Cells Exhibit Regulatory Properties During the Peri-Implantation Stage of Murine Pregnancy by Guzman-Genuino, Ruth Marian, Eldi, Preethi, Garcia-Valtanen, Pablo, Hayball, John D, Diener, Kerrilyn R

“…A successful outcome to pregnancy is dependent on the ability of the maternal uterine microenvironment to regulate inflammation processes and establish…”
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Antimicrobial Polymethacrylates Synthesized as Mimics of Tryptophan-Rich Cationic Peptides by Locock, Katherine E. S., Michl, Thomas D., Stevens, Natalie, Hayball, John D., Vasilev, Krasimir, Postma, Almar, Griesser, Hans J., Meagher, Laurence, Haeussler, Matthias

“…This study describes a facile and high yielding route to two series of polymethacrylates inspired by the naturally occurring, tryptophan-rich cationic…”
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Production of a Chikungunya Vaccine Using a CHO Cell and Attenuated Viral-Based Platform Technology by Eldi, Preethi, Cooper, Tamara H., Liu, Liang, Prow, Natalie A., Diener, Kerrilyn R., Howley, Paul M., Suhrbier, Andreas, Hayball, John D.

“…Vaccinia-based systems have been extensively explored for the development of recombinant vaccines. Herein we describe an innovative vaccinia virus…”
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EphB4 Expressing Stromal Cells Exhibit an Enhanced Capacity for Hematopoietic Stem Cell Maintenance by Nguyen, Thao M., Arthur, Agnieszka, Panagopoulos, Romana, Paton, Sharon, Hayball, John D., Zannettino, Andrew C.W., Purton, Louise E., Matsuo, Koichi, Gronthos, Stan

“…The tyrosine kinase receptor, EphB4, mediates cross‐talk between stromal and hematopoietic populations during bone remodeling, fracture repair and arthritis,…”
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Doxorubicin-Loaded Delta Inulin Conjugates for Controlled and Targeted Drug Delivery: Development, Characterization, and In Vitro Evaluation by Wang, Lixin, Song, Yunmei, Parikh, Ankit, Joyce, Paul, Chung, Rosa, Liu, Liang, Afinjuomo, Franklin, Hayball, John D, Petrovsky, Nikolai, Barclay, Thomas G, Garg, Sanjay

“…Delta inulin, also known as microparticulate inulin (MPI), was modified by covalently attaching doxorubicin to its nanostructured surface for use as a targeted…”
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From crescent to mature virion: vaccinia virus assembly and maturation by Liu, Liang, Cooper, Tamara, Howley, Paul M, Hayball, John D

“…Vaccinia virus (VACV) has achieved unprecedented success as a live viral vaccine for smallpox which mitigated eradication of the disease. Vaccinia virus has a…”
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Polyinosinic: Polycytidylic Acid and Murine Cytomegalovirus Modulate Expression of Murine IL-10 and IL-21 in White Adipose Tissue by Garcia-Valtanen, Pablo, Guzman-Genuino, Ruth Marian, Hayball, John D, Diener, Kerrilyn R

“…White adipose tissue (WAT) produces interleukin-10 and other immune suppressors in response to pathogen-associated molecular patterns (PAMPs). It also homes a…”
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Functionality of Proteins Bound to Plasma Polymer Surfaces by Coad, Bryan R, Scholz, Tanja, Vasilev, Krasimir, Hayball, John D, Short, Robert D, Griesser, Hans J

“…The deposition of a thin film layer by plasma polymerization enables the surface functionalization of a wide range of substrate materials for biointerfacial…”
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Synthesis and Characterization of pH-Sensitive Inulin Conjugate of Isoniazid for Monocyte-Targeted Delivery by Afinjuomo, Franklin, Barclay, Thomas G, Parikh, Ankit, Chung, Rosa, Song, Yunmei, Nagalingam, Gayathri, Triccas, Jamie, Wang, Lixin, Liu, Liang, Hayball, John D, Petrovsky, Nikolai, Garg, Sanjay

“…The use of particles for monocyte-mediated delivery could be a more efficient strategy and approach to achieve intracellular targeting and delivery of…”
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Attenuation of microglial and IL-1 signaling protects mice from acute alcohol-induced sedation and/or motor impairment by Wu, Yue, Lousberg, Erin L, Moldenhauer, Lachlan M, Hayball, John D, Robertson, Sarah A, Coller, Janet K, Watkins, Linda R, Somogyi, Andrew A, Hutchinson, Mark R

“…Highlight ► Behavioral preclincial evidence that microglial and IL-1 signaling contribute to acute alcohol actions highlights the importance of alcohol…”
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Aberrant Expression of High Mobility Group Box Protein 1 in the Idiopathic Inflammatory Myopathies by Day, Jessica, Otto, Sophia, Cash, Kathy, Eldi, Preethi, Hissaria, Pravin, Proudman, Susanna, Limaye, Vidya, Hayball, John D

“…High Mobility Group Box Protein 1 (HMGB1) is a DNA-binding protein that exerts inflammatory or pro-repair effects upon translocation from the nucleus. We…”
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Comparative Analysis of Immune Checkpoint Molecules and Their Potential Role in the Transmissible Tasmanian Devil Facial Tumor Disease by Flies, Andrew S, Blackburn, Nicholas B, Lyons, Alan Bruce, Hayball, John D, Woods, Gregory M

“…Immune checkpoint molecules function as a system of checks and balances that enhance or inhibit immune responses to infectious agents, foreign tissues, and…”
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Cytolytic DNA vaccine encoding lytic perforin augments the maturation of- and antigen presentation by- dendritic cells in a time-dependent manner by Wijesundara, Danushka K., Yu, Wenbo, Quah, Ben J. C., Eldi, Preethi, Hayball, John D., Diener, Kerrilyn R., Voskoboinik, Ilia, Gowans, Eric J., Grubor-Bauk, Branka

“…The use of cost-effective vaccines capable of inducing robust CD8 + T cell immunity will contribute significantly towards the elimination of persistent viral…”
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Transient dominant host-range selection using Chinese hamster ovary cells to generate marker-free recombinant viral vectors from vaccinia virus by Liu, Liang, Cooper, Tamara, Eldi, Preethi, Garcia-Valtanen, Pablo, Diener, Kerrilyn R, Howley, Paul M, Hayball, John D

“…Recombinant vaccinia viruses (rVACVs) are promising antigen-delivery systems for vaccine development that are also useful as research tools. Two common methods…”
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Arthritogenic Alphavirus Vaccines: Serogrouping Versus Cross-Protection in Mouse Models by Nguyen, Wilson, Nakayama, Eri, Yan, Kexin, Tang, Bing, Le, Thuy T, Liu, Liang, Cooper, Tamara H, Hayball, John D, Faddy, Helen M, Warrilow, David, Allcock, Richard J N, Hobson-Peters, Jody, Hall, Roy A, Rawle, Daniel J, Lutzky, Viviana P, Young, Paul, Oliveira, Nidia M, Hartel, Gunter, Howley, Paul M, Prow, Natalie A, Suhrbier, Andreas

“…Chikungunya virus (CHIKV), Ross River virus (RRV), o'nyong nyong virus (ONNV), Mayaro virus (MAYV) and Getah virus (GETV) represent arthritogenic alphaviruses…”
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