Search Results - "Hayashi, Tatsuyuki"

Improved anti‐tumor activity of stabilized anthracycline polymeric micelle formulation, NC‐6300 by Harada, Mitsunori, Bobe, Iulian, Saito, Hiroyuki, Shibata, Naoya, Tanaka, Ryosuke, Hayashi, Tatsuyuki, Kato, Yasuki

“…Anthracyclines have long been considered to be among the most active agents clinically available for the treatment of breast cancer despite their toxicity. To…”
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NC‐6300, an epirubicin‐incorporating micelle, extends the antitumor effect and reduces the cardiotoxicity of epirubicin by Takahashi, Amane, Yamamoto, Yoshiyuki, Yasunaga, Masahiro, Koga, Yoshikatsu, Kuroda, Jun‐ichiro, Takigahira, Misato, Harada, Mitsunori, Saito, Hiroyuki, Hayashi, Tatsuyuki, Kato, Yasuki, Kinoshita, Taira, Ohkohchi, Nobuhiro, Hyodo, Ichinosuke, Matsumura, Yasuhiro

“…Epirubicin is widely used to treat various human tumors. However, it is difficult to achieve a sufficient antitumor effect because of dosage limitation to…”
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Prolonged circulation and in vivo efficacy of recombinant human granulocyte colony-stimulating factor encapsulated in polymeric micelles by Harada, Mitsunori, Ohuchi, Miho, Hayashi, Tatsuyuki, Kato, Yasuki

“…To improve the pharmacokinetics of granulocyte colony-stimulating factor (G-CSF) and decrease dosing frequency, polyethylene glycol polyglutamate block…”
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Early immune reaction after reduced-intensity cord-blood transplantation for adult patients by KISHI, Yukiko, KAMI, Masahiro, MASUOKA, Kazuhiro, WAKE, Atsushi, MORINAGA, Shinichi, KANEMARU, Mineo, HAYASHI, Tatsuyuki, TANAKA, Yuji, TANIGUCHI, Shuichi, MIYAKOSHI, Shigesaburo, KANDA, Yoshinobu, MURASHIGE, Naoko, TESHIMA, Takanori, KUSUMI, Eiji, HARA, Shigeo, MATSUMURA, Tomoko, YUJI, Koichiro

“…To investigate immune reactions after reduced-intensity cord-blood transplantation (RI-CBT). We reviewed medical records of 57 adult RI-CBT recipients…”
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Successful Engraftment After Reduced-Intensity Umbilical Cord Blood Transplantation for Adult Patients with Advanced Hematological Diseases by MIYAKOSHI, Shigesaburo, YUJI, Koichiro, MORI, Shin-Ichiro, MORINAGA, Shin-Ichi, MUTO, Yoshitomo, MASUO, Shigeru, KANEMARU, Mineo, HAYASHI, Tatsuyuki, TAKAUE, Yoichi, TANIGUCHI, Shuichi, KAMI, Masahiro, KUSUMI, Eiji, KISHI, Yukiko, KOBAYASHI, Kazuhiko, MURASHIGE, Naoko, HAMAKI, Tamae, KIM, Sung-Won, UEYAMA, Jun-Ichi

“…Purpose: The purpose of this research was to evaluate the feasibility of reduced-intensity unrelated cord-blood transplantation (RI-UCBT) in adult patients…”
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Thalidomide Treatment for Immunoglobulin D Multiple Myeloma in a Patient on Chronic Hemodialysis by HAYASHI, Tatsuyuki, YAMAGUCHI, Izumi, SAITOH, Hiroki, TAKAGI, Masao, NONAKA, Yasunobu, NOMURA, Takeo

“…A 64-year-old Japanese man suffering from IgD λ myeloma and renal failure requiring chronic hemodialysis was treated with thalidomide. Serum IgD concentration…”
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Heparin-induced Thrombocytopenia and Thrombosis in a Patient with Polycythemia Vera by HAYASHI, Tatsuyuki, SUYAMA, Yuki, KANEKO, Mitsunobu, OKAMURA, Juri, NAKAO, Yutaka, NONAKA, Yasunobu, NOMURA, Takeo

“…A 75-year-old Japanese woman with polycythemia vera was admitted to our hospital in January 2003 with suspected pulmonary thromboembolism. After administration…”
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Pyomyositis as a focus of infection in hematological disorders: A report of 3 cases by HAYASHI, Tatsuyuki, NOZAKI, Miho, NONAKA, Yasunobu, OHASHI, Kazuteru, SAKAMAKI, Hisashi, NOMURA, Takeo

“…The cases of 3 patients with pyomyositis associated with hematological disorders are reported. A 40-year-old man in the blastic phase of chronic myelogenous…”
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Effect of combined treatment with the epirubicin‐incorporating micelles (NC‐6300) and 1,2‐diaminocyclohexane platinum (II)‐incorporating micelles (NC‐4016) on a human gastric cancer model by Yamamoto, Yoshiyuki, Hyodo, Ichinosuke, Takigahira, Misato, Koga, Yoshikatsu, Yasunaga, Masahiro, Harada, Mitsunori, Hayashi, Tatsuyuki, Kato, Yasuki, Matsumura, Yasuhiro

“…Anticancer agent‐incorporating polymeric micelles accumulate effectively in tumors via the enhanced permeability and retention effect to exert potent antitumor…”
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Combination therapy with dendritic cell vaccine and IL-2 encapsulating polymeric micelles enhances intra-tumoral accumulation of antigen-specific CTLs by Miki, Kenji, Nagaoka, Koji, Harada, Mitsunori, Hayashi, Tatsuyuki, Jinguji, Hidemasa, Kato, Yasuki, Maekawa, Ryuji

“…Dendritic cell (DC) vaccine is a promising immunotherapy for cancer due to its ability to induce antigen-specific CTLs efficiently. However, a number of…”
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Abstract 2648: Enhanced antitumor effect of anti tissue factor (TF) antibody-conjugated epirubicin-incorporating polymeric micelles in human cancer xenografts with high TF expression by Yamamoto, Yoshiyuki, Hyodo, Ichinosuke, Koga, Yoshikatsu, Tsumura, Ryo, Sato, Ryuta, Obonai, Toshihumi, Fuchigami, Hirobumi, Kudo, Masahisa, Yasunaga, Masahiro, Harada, Mitsunori, Hayashi, Tatsuyuki, Kato, Yasuki, Matsumura, Yasuhiro

“…Background: Anticancer agent-incorporating polymeric micelles, categorized as passive targeting agents, are expected to accumulate in tumors based on the…”
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Abstract 4525: Combined antitumor activity of the epirubicin-incorporating polymeric micelle NC-6300 and the DACHPt-incorporating polymeric micelle NC-4016 in mice bearing human gastric cancer xenografts by Yamamoto, Yoshiyuki, Hyodo, Ichinosuke, Takigahira, Misato, Koga, Yoshikatsu, Yasunaga, Masahiro, Harada, Mitsunori, Hayashi, Tatsuyuki, Kato, Yasuki, Matsumura, Yasuhiro

“…Background: Several anticancer agent (ACA)-incorporating polymeric micelles are known to accumulate effectively in tumors and exert sufficient antitumor…”
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Clinical significance of phenotypic features of blasts in patients with myelodysplastic syndrome by Ogata, Kiyoyuki, Nakamura, Kyoko, Yokose, Norio, Tamura, Hideto, Tachibana, Mikiko, Taniguchi, Osamu, Iwakiri, Rika, Hayashi, Tatsuyuki, Sakamaki, Hisashi, Murai, Yoshiro, Tohyama, Kaoru, Tomoyasu, Shigeru, Nonaka, Yasunobu, Mori, Mayumi, Dan, Kazuo, Yoshida, Yataro

“…Knowledge of the blast phenotype in myelodysplastic syndrome (MDS) would be valuable, as in other malignancies, but remains sparse. This is mainly because MDS…”
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Early central nervous system complications after reduced-intensity stem cell transplantation by Kishi, Yukiko, Miyakoshi, Shigesaburo, Kami, Masahiro, Ikeda, Masayuki, Katayama, Yuta, Murashige, Naoko, Kusumi, Eiji, Yuji, Koichiro, Kobayashi, Kazuhiko, Kato, Daisuke, Hamaki, Tamae, Matsumura, Tomoko, Kim, Sung-Won, Morinaga, Shinichi, Mori, Shinichiro, Kanemaru, Mineo, Hayashi, Tatsuyuki, Takaue, Yoichi, Taniguchi, Shuichi

“…To investigate clinical characteristics of early central nervous system (CNS) complications after reduced-intensity stem cell transplantation (RIST), we…”
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Treatment strategy for reducing the risk of rituximab-induced cytokine release syndrome in patients with intravascular large B-cell lymphoma: a case report and review of the literature by Makino, Katsuhiro, Nakata, Jumi, Kawachi, Satoru, Hayashi, Tatsuyuki, Nakajima, Atsuo, Yokoyama, Munehiro

“…Intravascular large B-cell lymphoma is a rare aggressive disseminated disease characterized by the presence of lymphoma cells in small vessels without…”
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Abstract LB-11: Reduced cardiotoxicity and improved antitumor effect of the epirubicin-incorporating micelle NC-6300 in a hepatocellular carcinoma model by Yamamoto, Yoshiyuki, Hyodo, Ichinosuke, Takahashi, Amane, Yasunaga, Masahiro, Koga, Yoshikatsu, Harada, Mitsunori, Saito, Hiroyuki, Tanaka, Ryosuke, Hayashi, Tatsuyuki, Kato, Yasuki, Matsumura, Yasuhiro

“…Background: Epirubicin, an anthracycline antitumor drug, has been approved for the treatment of various human tumors. However, epirubicin has significant…”
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NC-6301, a polymeric micelle rationally optimized for effective release of docetaxel, is potent but is less toxic than native docetaxel in vivo by Harada, Mitsunori, Iwata, Caname, Saito, Hiroyuki, Ishii, Kenta, Hayashi, Tatsuyuki, Yashiro, Masakazu, Hirakawa, Kosei, Miyazono, Kohei, Kato, Yasuki, Kano, Mitsunobu R

“…Drug release rate is an important factor in determining efficacy and toxicity of nanoscale drug delivery systems. However, optimization of the release rate in…”
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Angiotropic B-Cell Lymphoma Presenting with Progressive Dementia: An Autopsy Case and Review of the Literature in Japan by HAYASHI, Tatsuyuki, WATANABE, Eiichi, OGAWA, Maki, TERAKURA, Moriyuki, NONAKA, Yasunobu, HIRANO, Masanori, INOUE, Kiyoshi, IIZUKA, Tetsuji, OKA, Hiroshi, SUZUKI, Tsunemichi, MORI, Shigeo

“…We report an autopsy case of angiotropic lymphoma and review the literature in Japan. A 68-year-old female presented with transient right facial nerve palsy,…”
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Diffuse B-cell lymphoma associated with hemophagocytic syndrome by Suzuki, T, Nonaka, Y, Hayashi, T, Nomura, T, Ogawa, M, Mori, S

“…The patient was a 49-year-old woman who came to our hospital with a chief complaint of fever. She was admitted due to hepatosplenomegaly and pancytopenia. We…”
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A case of hemolysis induced by lansoprazole by Suzuki, T, Hayashi, T, Nonaka, Y, Hirano, M, Nomura, T, Miyazawa, I, Ishikawa, F, Kakiuchi, T

“…Hemolytic anemia and possible aplastic crisis with symptoms including jaundice, general fatigue and dark urine developed in a man being treated only by…”
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