Search Results - "Hayashi, Shizu"

The Lung Tissue Microbiome in Chronic Obstructive Pulmonary Disease by SZE, Marc A, DIMITRIU, Pedro A, HAYASHI, Shizu, ELLIOTT, W. Mark, MCDONOUGH, John E, GOSSELINK, John V, COOPER, Joel, SIN, Don D, MOHN, William W, HOGG, James C

“…Based on surface brushings and bronchoalveolar lavage fluid, Hilty and coworkers demonstrated microbiomes in the human lung characteristic of asthma and…”
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Host Response to the Lung Microbiome in Chronic Obstructive Pulmonary Disease by Sze, Marc A, Dimitriu, Pedro A, Suzuki, Masaru, McDonough, John E, Campbell, Josh D, Brothers, John F, Erb-Downward, John R, Huffnagle, Gary B, Hayashi, Shizu, Elliott, W Mark, Cooper, Joel, Sin, Don D, Lenburg, Marc E, Spira, Avrum, Mohn, William W, Hogg, James C

“…The relatively sparse but diverse microbiome in human lungs may become less diverse in chronic obstructive pulmonary disease (COPD). This article examines the…”
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Decreased Histone Deacetylase Activity in Chronic Obstructive Pulmonary Disease by Ito, Kazuhiro, Ito, Misako, Elliott, W. Mark, Cosio, Borja, Caramori, Gaetano, Kon, Onn Min, Barczyk, Adam, Hayashi, Shizu, Adcock, Ian M, Hogg, James C, Barnes, Peter J

“…The balance between histone deacetylase activity and histone acetyltransferase activity is one of the mechanisms controlling and limiting inflammatory cell…”
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Differential Expression of Tissue Repair Genes in the Pathogenesis of Chronic Obstructive Pulmonary Disease by GOSSELINK, John V, HAYASHI, Shizu, PIERCE, Richard A, PATTERSON, Alex, COOPER, Joel, HOGG, James C, ELLIOTT, W. Mark, LI XING, CHAN, Becky, LUOJIA YANG, WRIGHT, Claire, DON SIN, PARE, Peter D, PIERCE, John A

“…The airflow limitation that defines severity of chronic obstructive pulmonary disease (COPD) is caused by a combination of small airway obstruction and…”
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Comprehensive Gene Expression Profiles Reveal Pathways Related to the Pathogenesis of Chronic Obstructive Pulmonary Disease by Ning, Wen, Li, Chao-Jun, Kaminski, Naftali, Feghali-Bostwick, Carol A., Alber, Sean M., Di, Yuanpu P., Otterbein, Sherrie L., Song, Ruiping, Hayashi, Shizu, Zhou, Zhihong, Pinsky, David J., Watkins, Simon C., Pilewski, Joseph M., Sciurba, Frank C., Peters, David G., Hogg, James C., Augustine M. K. Choi, Vogelstein, Bert

“…To better understand the molecular basis of chronic obstructive pulmonary disease (COPD), we used serial analysis of gene expression (SAGE) and microarray…”
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Alveolar macrophage-epithelial cell interaction following exposure to atmospheric particles induces the release of mediators involved in monocyte mobilization and recruitment by Ishii, Hiroshi, Hayashi, Shizu, Hogg, James C, Fujii, Takeshi, Goto, Yukinobu, Sakamoto, Noriho, Mukae, Hiroshi, Vincent, Renaud, van Eeden, Stephan F

“…Studies from our laboratory have shown that human alveolar macrophages (AM) and bronchial epithelial cells (HBEC) exposed to ambient particles (PM10) in vitro…”
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Latent adenovirus infection in COPD by Hayashi, Shizu

“…We have concentrated on the adenovirus as the source of the heightened inflammatory response of the lungs of patients with COPD. We have concentrated in…”
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Patterns of Retention of Particulate Matter in Lung Tissues of Patients With COPD by Ling, Sean H., MSc, McDonough, John E., PhD, Gosselink, John V., BSc, Elliott, W. Mark, PhD, Hayashi, Shizu, PhD, Hogg, James C., MD, PhD, van Eeden, Stephan F., MD, PhD

“…Background Particulate matter (PM) is present in lung tissues of smokers and urban dwellers. This study was designed to quantify the burden of PM in different…”
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Role of genetic susceptibility to latent adenoviral infection and decreased lung function by Kasuga, Ikuma, Hogg, James C, Paré, Peter D, Hayashi, Shizu, Sedgwick, Edward G, Ruan, Jian, Wallace, Alison M, He, Jian-Qing, Zhang, Xiaozhu, Sandford, Andrew J

“…Summary Background Latent adenoviral infection may amplify cigarette smoke-induced lung inflammation and therefore play an important role in the development of…”
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Functional changes in aging polymorphonuclear leukocytes by TANJI-MATSUBA, K, VAN EEDEN, S. F, SAITO, Y, OKAZAWA, M, KLUT, M. E, HAYASHI, S, HOGG, J. C

“…Previous studies from our laboratory have shown that the expression of L-selectin on polymorphonuclear neutrophils (PMN) decreases as the cell ages in the…”
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Adenovirus infections and lung disease by Hayashi, Shizu, Hogg, James C

“…Adenovirus, particularly its E1A protein, has been investigated in the pathogenesis of chronic obstructive pulmonary disease (COPD). High levels of E1A DNA…”
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A gene expression signature of emphysema-related lung destruction and its reversal by the tripeptide GHK by Campbell, Joshua D, McDonough, John E, Zeskind, Julie E, Hackett, Tillie L, Pechkovsky, Dmitri V, Brandsma, Corry-Anke, Suzuki, Masaru, Gosselink, John V, Liu, Gang, Alekseyev, Yuriy O, Xiao, Ji, Zhang, Xiaohui, Hayashi, Shizu, Cooper, Joel D, Timens, Wim, Postma, Dirkje S, Knight, Darryl A, Lenburg, Marc E, Hogg, James C, Spira, Avrum

“…Chronic obstructive pulmonary disease (COPD) is a heterogeneous disease consisting of emphysema, small airway obstruction, and/or chronic bronchitis that…”
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Gene Expression Profiling in Patients with Chronic Obstructive Pulmonary Disease and Lung Cancer by Wang, I-Ming, Stepaniants, Sergey, Boie, Yves, Mortimer, James R, Kennedy, Brian, Elliott, Mark, Hayashi, Shizu, Loy, Leanna, Coulter, Silvija, Cervino, Sandra, Harris, Jennifer, Thornton, Michele, Raubertas, Richard, Roberts, Chris, Hogg, Jim C, Crackower, Michael, O'Neill, Gary, Pare, Peter D

“…Chronic obstructive lung disease (COPD) is a common and disabling lung disease for which there are few therapeutic options. We reasoned that gene expression…”
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Amplification of Inflammation in Emphysema and Its Association with Latent Adenoviral Infection by RETAMALES, IVAN, ELLIOTT, W. MARK, MESHI, BERNARD, COXSON, HARVEY O, PARE, PETER D, SCIURBA, FRANK C, ROGERS, ROBERT M, HAYASHI, SHIZU, HOGG, JAMES C

“…This study examines the hypothesis that the cigarette smoke-induced inflammatory process is amplified in severe emphysema and explores the association of this…”
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Patterns of Retention of Particulate Matter in Lung Tissues of Patients With COPD: Potential Role in Disease Progression by LING, Sean H, MCDONOUGH, John E, GOSSELINK, John V, ELLIOTT, W. Mark, HAYASHI, Shizu, HOGG, James C, VAN EEDEN, Stephen F

“…Particulate matter (PM) is present in lung tissues of smokers and urban dwellers. This study was designed to quantify the burden of PM in different lung…”
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Particulate Matter Induces Cytokine Expression in Human Bronchial Epithelial Cells by Fujii, Takeshi, Hayashi, Shizu, Hogg, James C, Vincent, Renaud, Van Eeden, Stephan F

“…The present study was designed to determine cytokines produced by primary human bronchial epithelial cells (HBECs) exposed to ambient air pollution particles…”
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Interaction of Alveolar Macrophages and Airway Epithelial Cells Following Exposure to Particulate Matter Produces Mediators that Stimulate the Bone Marrow by Fujii, Takeshi, Hayashi, Shizu, Hogg, James C, Mukae, Hiroshi, Suwa, Tatsushi, Goto, Yukinobu, Vincent, Renaud, van Eeden, Stephan F

“…Exposure to ambient air pollution particles with a diameter of < 10 microm (PM(10)) has been associated with increased cardiopulmonary morbidity and mortality…”
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Adenovirus E1A regulates lung epithelial ICAM-1 expression by interacting with transcriptional regulators at its promoter by Morimoto, Kiyoshi, Gosselink, John, Kartono, Aileen, Hogg, James C, Hayashi, Shizu, Ogawa, Emiko

“…We focused on the regulation of inflammatory mediator expression by adenovirus E1A in lung epithelial cells and the role of this viral protein in the…”
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Contribution of IL-1 beta and TNF-alpha to the initiation of the peripheral lung response to atmospheric particulates (PM10) by Ishii, Hiroshi, Fujii, Takeshi, Hogg, James C, Hayashi, Shizu, Mukae, Hiroshi, Vincent, Renaud, van Eeden, Stephan F

“…Alveolar macrophages (AM) play a key role in clearing atmospheric particulates from the lung surface and stimulating epithelial cells to produce…”
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Genes related to emphysema are enriched for ubiquitination pathways by Stepaniants, Sergey, Wang, I-Ming, Boie, Yves, Mortimer, James, Kennedy, Brian, Elliott, Mark, Hayashi, Shizu, Luo, Honglin, Wong, Jerry, Loy, Leanna, Coulter, Silvija, Roberts, Christopher J, Hogg, James C, Sin, Don D, O'Neill, Gary, Crackower, Michael, Morris, Melody, Paré, Peter D, Obeidat, Ma'en

“…Increased small airway resistance and decreased lung elasticity contribute to the airflow limitation in chronic obstructive pulmonary disease (COPD). The…”
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