Search Results - "Hayashi, Morimichi"

Pseudoirreversible inhibition elicits persistent efficacy of a sphingosine 1-phosphate receptor 1 antagonist by Maruyama, Yuya, Ohsawa, Yusuke, Suzuki, Takayuki, Yamauchi, Yuko, Ohno, Kohsuke, Inoue, Hitoshi, Yamamoto, Akitoshi, Hayashi, Morimichi, Okuhara, Yuji, Muramatsu, Wataru, Namiki, Kano, Hagiwara, Naho, Miyauchi, Maki, Miyao, Takahisa, Ishikawa, Tatsuya, Horie, Kenta, Hayama, Mio, Akiyama, Nobuko, Hirokawa, Takatsugu, Akiyama, Taishin

“…Sphingosine 1-phosphate receptor 1 (S1PR1), a G protein-coupled receptor, is required for lymphocyte trafficking, and is a promising therapeutic target in…”
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Spontaneous adenocarcinoma with giant cell formation in the accessory sex glands in a male Sprague-Dawley rat by Miyazaki, Shingo, Ogawa, Takashi, Onozato, Tomoya, Okuhara, Yuji, Nagasawa, Tatsuya, Hayashi, Morimichi

“…In this study, we report the features of an adenocarcinoma with giant cell formation spontaneously occurring in the accessory sex glands of a male 10-month-old…”
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Novel oestrogen receptor β-selective ligand reduces obesity and depressive-like behaviour in ovariectomized mice by Sasayama, Daimei, Sugiyama, Nobuhiro, Yonekubo, Shigeru, Pawlak, Akiko, Murasawa, Hiroyasu, Nakamura, Mie, Hayashi, Morimichi, Ogawa, Takashi, Moro, Makoto, Washizuka, Shinsuke, Amano, Naoji, Hongo, Kazuhiro, Ohnota, Hideki

“…Hormonal changes due to menopause can cause various health problems including weight gain and depressive symptoms. Multiple lines of evidence indicate that…”
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Strain differences in hepatic cytochrome P450 1A and 3A expression between Sprague-Dawley and Wistar rats by Kishida, Tomoyuki, Muto, Shin-ichi, Hayashi, Morimichi, Tsutsui, Masaru, Tanaka, Satoru, Murakami, Makoto, Kuroda, Junji

“…Expression of hepatic cytochrome P450 (CYP) isoforms was compared in Sprague-Dawley (SD) and Wistar (WI) rats, which are commonly used strains in preclinical…”
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Spontaneous cutaneous soft tissue sarcoma with differentiation into fibroblasts in a Sprague-Dawley rat by Ogawa, Takashi, Onozato, Tomoya, Okuhara, Yuji, Nagasawa, Tatsuya, Tamura, Toru, Hayashi, Morimichi

“…A small mass with an ulcer was found in the skin of the dorsal cervix of a 7-month-old male Sprague-Dawley rat. Histologically, the central region of the tumor…”
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Spontaneous adenocarcinoma with giant cell formation in the accessory sex glands in a male Sprague-Dawley rat by Shingo Miyazaki, Takashi Ogawa, Tomoya Onozato, Yuji Okuhara, Tatsuya Nagasawa, Morimichi Hayashi

“…[Abstract] : In this study, we report the features of an adenocarcinoma with giant cell formation spontaneously occurring in the accessory sex glands of a male…”
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Spontaneous cutaneous soft tissue sarcoma with differentiation into fibroblasts in a Sprague-Dawley rat by Ogawa, Takashi, Onozato, Tomoya, Okuhara, Yuji, Nagasawa, Tatsuya, Tamura, Toru, Hayashi, Morimichi

“…Abstract: A small mass with an ulcer was found in the skin of the dorsal cervix of a 7-month-old male Sprague-Dawley rat. Histologically, the central region of…”
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Embryonic mortality and intrauterine growth retardation (IUGR) associated with placental alterations in pregnant rats treated with methyl methanesulfonate (MMS) at the peri-implantation stage by Yokoi, Ryohei, Hayashi, Morimichi, Tamura, Toru, Kobayashi, Kazuo, Kuroda, Junji, Kusama, Hiroshi, Kagami, Hiroshi, Ono, Tamao

“…Embryonic mortality and intrauterine growth retardation (IUGR) are induced by exposure of rodents to xenobiotic agents during the pregastrulation period of…”
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Collaborative work on evaluation of ovarian toxicity 2) Two- or four-week repeated dose studies and fertility study of mifepristone in female rats by Tamura, Toru, Yokoi, Ryohei, Okuhara, Yuji, Harada, Chiho, Terashima, Yukari, Hayashi, Morimichi, Nagasawa, Tatsuya, Onozato, Tomoya, Kobayashi, Kazuo, Kuroda, Junji, Kusama, Hiroshi

“…In order to assess ovarian pathological changes and their relationship to changes in female fertility parameters, mifepristone, a progesterone receptor…”
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Spontaneous Subcutaneous Sarcoma in a 50-week-old Male Wistar Hannover GALAS Rat by Onozato, Tomoya, Tamura, Toru, Nagasawa, Tatsuya, Hayashi, Morimichi, Okuhara, Yuji, Kuroda, Junji

“…A subcutaneous mass was noted in the abdomen of a 50-week-old male Wistar Hannover GALAS rat. Histologically, the tumor was composed of vimentin-positive small…”
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Spontaneous Subcutaneous Sarcoma in a 50-week-old Male Wistar Hannover GALAS Rat by Onozato, Tomoya, Tamura, Toru, Nagasawa, Tatsuya, Hayashi, Morimichi, Okuhara, Yuji, Kuroda, Junji

“…Abstract：A subcutaneous mass was noted in the abdomen of a 50-week-old male Wistar Hannover GALAS rat. Histologically, the tumor was composed of…”
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Lack of Modifying Effect of Arctiin on ENU-Induced Uterine Carcinogenesis in ICR Mice by Okuhara, Yuji, Kitamura, Tsuyoshi, Hayashi, Morimichi, Nagasawa, Tatsuya, Tamura, Toru, Kuroda, Junji, Shibata, Nobuo, Mitsumori, Kunitoshi

“…The present study was performed to investigate the modifying effects of arctiin, a plant lignan isolated from Arctium lappa (burdock) seeds, on uterine…”
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A TIME-COURSE CHARACTERIZATION OF MALE REPRODUCTIVE TOXICITY IN RATS TREATED WITH METHYL METHANESULPHONATE (MMS) by KURIYAMA, Kazuya, YOKOI, Ryohei, KOBAYASHI, Kazuo, SUDA, Satoshi, HAYASHI, Morimichi, OZAWA, Shigenari, KURODA, Junji, TSUJII, Hirotada

“…Methyl methanesulphonate (MMS), a potent alkylating agent and testicular toxicant, was orally administered to rats for 5 days at doses of 20, 30, and 40 mg/kg…”
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Skeletal muscle cells derived from mouse skin cultures by Ohnota, Hideki, Nakazawa, Hiromi, Hayashi, Morimichi, Okuhara, Yuji, Honda, Takayuki, d’Azzo, Alessandra, Sekijima, Yoshiki

“…We have established a novel, simple, and highly reproducible method to generate skeletal muscle cells from mouse skin. Small pieces of skin from the back of…”
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Evaluation of testicular toxicity and sperm morphology in rats treated with methyl methanesulphonate (MMS) by Kuriyama, K.(Kissei Pharmaceutical Co. Ltd., Matsumoto, Nagano (Japan)), Kitamura, T, Yokoi, R, Hayashi, M, Kobayashi, K, Kuroda, J, Tsujii, H

“…Methyl methanesulphonate (MMS), a potent alkylating agent and testicular toxicant, was orally administered to rats for 5 days at 40 mg/kg. During the recovery…”
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Spontaneous bilateral thyroid follicular cell carcinoma (subtype: compact cellular carcinoma) with C-cell complexes in a male beagle by MIYAZAKI, Shingo, OGAWA, Takashi, ONOZATO, Tomoya, OKUHARA, Yuji, NAGASAWA, Tatsuya, HAYASHI, Morimichi

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Longitudinal analysis of motor symptoms and histopathology in woozy mice, a model of cerebellar ataxia by Hayashi, Takemitsu, Onozato, Tomoya, Wanajo, Isao, Hayashi, Morimichi, Takeda, Hiroo, Fujimori, Yoshikazu

“…Woozy (wz) mice develop ataxia and carry a mutation in the Sil1 gene. Homozygous wz mice have been characterized histopathologically, but no details of their…”
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Spontaneous adenocarcinoma with giant cell formation in the accessory sex glands in a male Sprague-Dawley rat by MIYAZAKI, Shingo, OGAWA, Takashi, ONOZATO, Tomoya, OKUHARA, Yuji, NAGASAWA, Tatsuya, HAYASHI, Morimichi

“…In this study, we report the features of an adenocarcinoma with giant cell formation spontaneously occurring in the accessory sex glands of a male 10-month-old…”
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Effect of Silodosin on Intraurethral Pressure Increase Induced by Hypogastric Nerve Stimulation in Dogs with Benign Prostatic Hyperplasia by TOMIYAMA, Yoshitaka, TATEMICHI, Satoshi, TADACHI, Mariko, KOBAYASHI, Shinya, HAYASHI, Morimichi, KOBAYASHI, Mamoru, YAMAZAKI, Yoshinobu, SHIBATA, Nobuo

“…We compared the urethral and cardiovascular effects of silodosin (selective α1A-adrenoceptor antagonist), a novel medication for benign prostatic hyperplasia…”
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Effect of Silodosin on Intraurethral Pressure Increase Induced by Hypogastric Nerve Stimulation in Dogs with Benign Prostatic Hyperplasia by TOMIYAMA, Yoshitaka, TATEMICHI, Satoshi, TADACHI, Mariko, KOBAYASHI, Shinya, HAYASHI, Morimichi, KOBAYASHI, Mamoru, YAMAZAKI, Yoshinobu, SHIBATA, Nobuo

“…We compared the urethral and cardiovascular effects of silodosin (selective α_ -adrenoceptor antagonist), a novel medication for benign prostatic hyperplasia…”
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