Search Results - "Hayama, Tadashi"

Matrix Effects in Mass Spectrometry Analysis by HAYAMA, Tadashi

“…Accurate determinations of the concentrations of analytes in complex matrix samples, such as agricultural, environmental, and biological, still present…”
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Discrimination of Malignant Pleural Mesothelioma Cell Lines Using Amino Acid Metabolomics with HPLC by Tomita, Ryoko, Nishijo, Nao, Hayama, Tadashi, Fujioka, Toshihiro

“…Malignant pleural mesothelioma (MPM) is a malignancy closely associated with asbestos exposure. Although early diagnosis provides a chance of effective…”
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Deep eutectic solvent extraction of cortisol and cortisone from human saliva followed by LC-UV analysis by Nishijo, Nao, Hayama, Tadashi, Tomita, Ryoko, Fujioka, Toshihiro

“…•A deep eutectic solvent was used to extract cortisol and cortisone.•The developed method provides a suitable enrichment factor.•This allowed the analysis of…”
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Recent development and trends in sample extraction and preparation for mass spectrometric analysis of nucleotides, nucleosides, and proteins by Hayama, Tadashi, Ohyama, Kaname

“…•Critical step is sample extraction and preparation in analysis of biomolecules.•Materials and techniques are improving for extracting nucleotides and…”
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Fluorous and Fluorogenic Derivatization for Selective Liquid Chromatographic Analysis of Cyanide in Human Plasma by TOMITA, Ryoko, HAYAMA, Tadashi, NISHIJO, Nao, FUJIOKA, Toshihiro

“…A liquid chromatographic (LC) method with fluorous derivatization for the determination of cyanide in human plasma is described. In this method, the cyanide…”
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Multiple phosphorylated protein selective analysis via fluorous derivatization and liquid chromatography-electrospray ionization-mass spectrometry analysis by Kawasue, Shimba, Sakaguchi, Yohei, Koga, Reiko, Hayama, Tadashi, Yoshida, Hideyuki, Nohta, Hitoshi

“…Post-translational modification of proteins is involved in protein function and higher-order structure. Among such modification, phosphorylation is an…”
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Liquid Chromatographic Determination of o-Phosphoethanolamine in Human Plasma Using Fluorescent Derivatization by Tomita, Ryoko, Hayama, Tadashi, Nishijo, Nao, Sogawa, Rintaro, Shimanoe, Chisato, Fujioka, Toshihiro

“…In this study, an HPLC analysis method using pre-column derivatization with 6-aminoquinolyl-N-hydroxysuccinimidyl carbamate (AQC) was developed for the…”
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Fluorous affinity-based separation techniques for the analysis of biogenic and related molecules by Hayama, Tadashi, Yoshida, Hideyuki, Yamaguchi, Masatoshi, Nohta, Hitoshi

“…•Perfluoroalkyl compounds have a remarkable fluorous affinity for one another.•This specific affinity enabled selective analysis of targets in complex…”
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Quantification of Casein in Baked Food Products by Selective Analysis of Phosphorylated Peptides Using Fluorous Derivatization with Liquid Chromatography-Tandem Mass Spectrometry Method by Kawasue, Shimba, Sakaguchi, Yohei, Koga, Reiko, Hayama, Tadashi, Yoshida, Hideyuki, Nohta, Hitoshi

“…Casein is one of the allergen proteins present in milk. Therefore, a quantification method for the selective analysis of casein using fluorous derivatization…”
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Fluorous-assisted metal chelate affinity extraction for nucleotides followed by HILIC-MS/MS analysis by Kiyokawa, Ena, Hayama, Tadashi, Yoshida, Hideyuki, Yamaguchi, Masatoshi, Nohta, Hitoshi

“…We herein developed a selective method for the determination of nucleotides by fluorous-assisted metal chelate affinity extraction followed by hydrophilic…”
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Assessment of Anticancer Drug Effects on Pancreatic Cancer Cells under Glucose-Depleted Conditions Using Intracellular and Extracellular Amino Acid Metabolomics by Tomita, Ryoko, Todoroki, Kenichiro, Hayama, Tadashi, Yoshida, Hideyuki, Fujioka, Toshihiro, Nakashima, Manabu, Yamaguchi, Masatoshi, Nohta, Hitoshi

“…Previously, we developed a method to evaluate states of cells treated with anticancer drugs via the comprehensive analysis of amino acids, termed amino acid…”
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Selective liquid-chromatographic determination of native fluorescent biogenic amines in human urine based on fluorous derivatization by Sakaguchi, Yohei, Yoshida, Hideyuki, Hayama, Tadashi, Itoyama, Miki, Todoroki, Kenichiro, Yamaguchi, Masatoshi, Nohta, Hitoshi

“…A liquid chromatographic (LC) derivatization method for simple and selective determination of catecholamines and indoleamines in human urine has been…”
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Direct tandem mass spectrometric analysis of amino acids in plasma using fluorous derivatization and monolithic solid-phase purification by Tamashima, Erina, Hayama, Tadashi, Yoshida, Hideyuki, Imakyure, Osamu, Yamaguchi, Masatoshi, Nohta, Hitoshi

“…[Display omitted] •A novel tandem mass spectrometric analysis method for amino acids was developed.•Amino acids were derivatized with a fluorous aldehyde by…”
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Fluorous-assisted metal chelate affinity extraction technique for analysis of protein kinase activity by Hayama, Tadashi, Kiyokawa, Ena, Yoshida, Hideyuki, Imakyure, Osamu, Yamaguchi, Masatoshi, Nohta, Hitoshi

“…We have developed a fluorous affinity-based extraction method for measurement of protein kinase activity. In this method, a fluorescent peptide substrate was…”
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Highly sensitive and selective derivatization-LC method for biomolecules based on fluorescence interactions and fluorous separations by Todoroki, Kenichiro, Yoshida, Hideyuki, Hayama, Tadashi, Itoyama, Miki, Nohta, Hitoshi, Yamaguchi, Masatoshi

“…A fluorescence derivatization LC method is a powerful tool for the analysis with high sensitivity and selectivity of biological compounds. In this review, we…”
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Fluorous derivatization and fluorous-phase separation for fluorometric determination of naproxen and felbinac in human plasma by Sakaguchi, Yohei, Yoshida, Hideyuki, Hayama, Tadashi, Yoshitake, Makoto, Itoyama, Miki, Todoroki, Kenichiro, Yamaguchi, Masatoshi, Nohta, Hitoshi

“…Fluorous derivatization followed by fluorous-phase liquid chromatographic (LC) separation exploits the affinity between perfluoroalkyl compounds for highly…”
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Fully automated reagent peak-free liquid chromatography fluorescence analysis of highly polar carboxylic acids using a column-switching system and fluorous scavenging derivatization by Todoroki, Kenichiro, Hashimoto, Hiroki, Machida, Kazuyuki, Itoyama, Miki, Hayama, Tadashi, Yoshida, Hideyuki, Nohta, Hitoshi, Nakashima, Manabu, Yamaguchi, Masatoshi

“…In this study, we combined a column‐switching system with a fluorous scavenging derivatization method to develop a fully automated reagent peak‐free LC…”
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Determination of tetrabromobisphenol A in human serum by liquid chromatography–electrospray ionization tandem mass spectrometry by Hayama, Tadashi, Yoshida, Hideyuki, Onimaru, Suzuko, Yonekura, Sayuri, Kuroki, Hiroaki, Todoroki, Kenichiro, Nohta, Hitoshi, Yamaguchi, Masatoshi

“…A method for the determination of tetrabromobisphenol A (TBBPA) in human serum utilizing solid-phase extractions (SPEs) and liquid chromatography (LC) with…”
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フルオラス相互作用を利用した生体関連物質の選択的LC分析法開発 by 巴山, 忠

“…「1. はじめに」 高速液体クロマトグラフィー(HPLC)は最も汎用されている分離分析手法の1つであり, 生体成分など複雑な構成をした試料の測定法として極めて有用である. 最近では, 超高速液体クロマトグラフィーに代表されるように, 分析装置の改良に伴った高速化・高感度化の向上が著しく,…”
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フルオラスケミストリーを駆使した生体関連物質の高選択的分析 by 巴山, 忠

“…「1. はじめに」フルオラスとは, 「親フルオロカーボン性の」という意味の造語であり, パーフルオロアルキル鎖同士のみが示す極性に依存しない特異的な親和性のことを指す. その詳細な原理についてはいまだ議論の余地があるが, C-F結合の低い分極率が, 疎水性・疎油性に起因し,…”
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