Search Results - "Hayakawa, Mineji"

Pathophysiology of Trauma-Induced Coagulopathy and Management of Critical Bleeding Requiring Massive Transfusion by Gando, Satoshi, Hayakawa, Mineji

“…Trauma-induced coagulopathy is caused by multiple factors, such as anemia, hemodilution, hypothermia, acidosis, shock, and serious trauma itself, which affects…”
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Comparison of results obtained using clot-fibrinolysis waveform analysis and global fibrinolysis capacity assay with rotational thromboelastography by Tsuchida, Takumi, Hayakawa, Mineji, Kumano, Osamu

“…Global fibrinolysis assays detect the fibrinolysis time of clot dissolution using tissue-type plasminogen activator (tPA). Two such assays, clot-fibrinolysis…”
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Intensive care with extracorporeal membrane oxygenation rewarming in accident severe hypothermia (ICE-CRASH) study: a protocol for a multicentre prospective, observational study in Japan by Takauji, Shuhei, Hayakawa, Mineji

“…IntroductionAccidental hypothermia (AH) is a rare but critical disease, leading to death in severe cases. In recent decades, extracorporeal membrane…”
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External Validation of the Two Newly Proposed Criteria for Assessing Coagulopathy in Sepsis by Yamakawa, Kazuma, Yoshimura, Jumpei, Ito, Takashi, Hayakawa, Mineji, Hamasaki, Toshimitsu, Fujimi, Satoshi

“…Two different criteria for evaluating coagulopathy in sepsis were recently released: sepsis-induced coagulopathy (SIC) and sepsis-associated coagulopathy…”
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Coagulation phenotypes in sepsis and effects of recombinant human thrombomodulin: an analysis of three multicentre observational studies by Kudo, Daisuke, Goto, Tadahiro, Uchimido, Ryo, Hayakawa, Mineji, Yamakawa, Kazuma, Abe, Toshikazu, Shiraishi, Atsushi, Kushimoto, Shigeki

“…A recent randomised trial showed that recombinant thrombomodulin did not benefit patients who had sepsis with coagulopathy and organ dysfunction. Several…”
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Minocycline Prevents the Impairment of Hippocampal Long-Term Potentiation in the Septic Mouse by Hoshino, Koji, Hayakawa, Mineji, Morimoto, Yuji

“…ABSTRACTSepsis-associated encephalopathy is a major complication during sepsis, and an effective treatment remains unknown. Although minocycline (MINO) has…”
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Hyperoxia for accidental hypothermia and increased mortality: a post-hoc analysis of a multicenter prospective observational study by Yamamoto, Ryo, Yoshizawa, Jo, Takauji, Shuhei, Hayakawa, Mineji, Sasaki, Junichi

“…Supraphysiologic oxygen administration causes unfavorable clinical outcomes in various diseases, including traumatic brain injury, post-cardiac arrest…”
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Benefit profile of anticoagulant therapy in sepsis: a nationwide multicentre registry in Japan by Yamakawa, Kazuma, Umemura, Yutaka, Hayakawa, Mineji, Kudo, Daisuke, Sanui, Masamitsu, Takahashi, Hiroki, Yoshikawa, Yoshiaki, Hamasaki, Toshimitsu, Fujimi, Satoshi

“…Little evidence supports anticoagulant therapy as effective adjuvant therapy to reduce mortality overall in sepsis. However, several studies suggest that…”
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Author Response Letter: "Correspondence: Is there an association between centre volume and survival or neurological outcomes among out-of-hospital cardiac arrest patients?" by Tsuchida, Takumi, Hayakawa, Mineji

“…Keywords: Cardiopulmonary resuscitation, Hospital volume, Neurological outcome, Out-of-hospital cardiac arrest, Prediction, Prognosis…”
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Screening itself for disseminated intravascular coagulation may reduce mortality in sepsis: A nationwide multicenter registry in Japan by Umemura, Yutaka, Yamakawa, Kazuma, Hayakawa, Mineji, Hamasaki, Toshimitsu, Fujimi, Satoshi

“…Screening of patients with sepsis for disseminated intravascular coagulation (DIC) has been recommended in several guidelines. However, DIC screening is still…”
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A Nationwide Comparison Between Sepsis-2 and Sepsis-3 Definition in Japan by Takauji, Shuhei, Hayakawa, Mineji, Fujita, Satoshi

“…Background: Currently, it remains controversial whether the Sepsis-3 definition provides the most appropriate criteria for clinical use. The purpose of this…”
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Electrocardiogram monitoring as a predictor of neurological and survival outcomes in patients with out-of-hospital cardiac arrest: a single-center retrospective observational study by Takahashi, Masaki, Ogura, Kentaro, Goto, Tadahiro, Hayakawa, Mineji

“…This study hypothesized that monitoring electrocardiogram (ECG) waveforms in patients with out-of-hospital cardiac arrest (OHCA) could have predictive value…”
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Soluble thrombomodulin ameliorates aberrant hemostasis after rewarming in a rat accidental hypothermia model by Takauji, Shuhei, Tanaka, Hiroki, Hayakawa, Mineji, Horioka, Kie, Isozaki, Shotaro, Konishi, Hiroaki

“…Accidental hypothermia (AH) sometimes leads to coagulation disorder, especially in severe AH. We previously demonstrated that intrasplenic platelet activation…”
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Optimal Antithrombin Activity Threshold for Initiating Antithrombin Supplementation in Patients With Sepsis-Induced Disseminated Intravascular Coagulation: A Multicenter Retrospective Observational Study by Hayakawa, Mineji, Yamakawa, Kazuma, Kudo, Daisuke, Ono, Kota

“…Low-dose antithrombin supplementation therapy (1500 IU/d for 3 days) improves outcomes in patients with sepsis-induced disseminated intravascular coagulation…”
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Fibrinolytic system activation immediately following trauma was quickly and intensely suppressed in a rat model of severe blunt trauma by Hayakawa, Mineji, Tsuchida, Takumi, Honma, Yoshinori, Mizugaki, Asumi, Ooyasu, Takayoshi, Yoshida, Tomonao, Saito, Tomoyo, Katabami, Kenichi, Wada, Takeshi, Maekawa, Kunihiko

“…In severe trauma, excessive fibrinolytic activation is associated with an increase in the transfusion volume and mortality rate. However, in the first several…”
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The Vasopressin Loading for Refractory septic shock (VALOR) study: a prospective observational study by Nakamura, Kensuke, Nakano, Hidehiko, Ikechi, Daisuke, Mochizuki, Masaki, Takahashi, Yuji, Koyama, Yasuaki, Hashimoto, Hideki, Abe, Toshikazu, Hayakawa, Mineji, Yamakawa, Kazuma

“…Vasopressin is a second-line vasoactive agent for refractory septic shock. Vasopressin loading is not generally performed because of the lack of evidence for…”
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Simultaneous prognostic score validation in patients with out-of-hospital cardiac arrest by a post-hoc analysis based on national multicenter registry by Tsuchida, Takumi, Ono, Kota, Takahashi, Masaki, Hayamaizu, Mariko, Mizugaki, Asumi, Maekawa, Kunihiko, Wada, Takeshi, Hayakawa, Mineji

“…Using a nationwide multicenter prospective registry in Japan’s data, we calculated prognostic and predictive scores, including the Out-of-Hospital Cardiac…”
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Multiple Retroperitoneal Abscesses Caused by Citrobacter koseri Are Associated with a Poor Prognosis by Matsuura, Yuki, Murashita, Mone, Oyasu, Takayoshi, Hayakawa, Mineji, Tsuchida, Takumi

“…Citrobacter koseri causes opportunistic infections in various organs. We herein report an 84-year-old man with diabetes mellitus who presented to our hospital…”
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Ductus arteriosus banding to regulate excessive pulmonary blood flow in a neonate with necrotizing enterocolitis and complex congenital heart disease, including pulmonary atresia and total anomalous pulmonary venous return: a case report by Oyasu, Takayoshi, Hayakawa, Mineji, Ebuoka, Noriyoshi, Oba, Junichi

“…Patients with right isomerism have accompanying complex congenital heart disease, which is characterized by pulmonary atresia and total anomalous pulmonary…”
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Impact of extracorporeal membrane oxygenation treatments on acquired von Willebrand syndrome in patients with out-of-hospital cardiac arrest: a retrospective observational study by Chiba, Yuki, Goto, Kota, Suzuki, Misako, Horiuchi, Hisanori, Hayakawa, Mineji

“…Von Willebrand factor (vWF) plays a crucial role in hemostasis, acting as a key factor for platelet adhesion/aggregation and as a transport protein for…”
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