Search Results - "Hay, Colin W"

Tissue control of androgen action: The ups and downs of androgen receptor expression by Hunter, Irene, Hay, Colin W., Esswein, Bianca, Watt, Kate, McEwan, Iain J.

“…The hormone testosterone plays crucial roles during male development and puberty and throughout life, as an anabolic regulator of muscle and bone structure and…”
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The impact of point mutations in the human androgen receptor: classification of mutations on the basis of transcriptional activity by Hay, Colin W, McEwan, Iain J

“…Androgen receptor mediated signaling drives prostate cancer cell growth and survival. Mutations within the receptor occur infrequently in prostate cancer prior…”
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An Sp1 Modulated Regulatory Region Unique to Higher Primates Regulates Human Androgen Receptor Promoter Activity in Prostate Cancer Cells by Hay, Colin W, Hunter, Irene, MacKenzie, Alasdair, McEwan, Iain J

“…Androgen receptor (AR) mediated signalling is necessary for normal development of the prostate gland and also drives prostate cancer (PCa) cell growth and…”
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Relative contribution of PDX-1, MafA and E47/β2 to the regulation of the human insulin promoter by Docherty, Hilary M., Hay, Colin W., Ferguson, Laura A., Barrow, John, Durward, Elaine, Docherty, Kevin

“…The insulin promoter binds a number of tissue-specific and ubiquitous transcription factors. Of these, the homoeodomain protein PDX-1 (pancreatic duodenal…”
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Comparative analysis of insulin gene promoters : Implications for diabetes research by HAY, Colin W, DOCHERTY, Kevin

“…DNA sequences that regulate expression of the insulin gene are located within a region spanning approximately 400 bp that flank the transcription start site…”
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Pancreatic transcription factors and their role in the birth, life and survival of the pancreatic β cell by Bernardo, Andreia S., Hay, Colin W., Docherty, Kevin

“…In recent years major progress has been made in understanding the role of transcription factors in the development of the endocrine pancreas in the mouse. Here…”
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Interactions of Abiraterone, Eplerenone, and Prednisolone with Wild-type and Mutant Androgen Receptor: A Rationale for Increasing Abiraterone Exposure or Combining with MDV3100 by RICHARDS, Juliet, AI CHIIN LIM, MCEWAN, Lain J, DE BONO, Johann S, ATTARD, Gerhardt, HAY, Colin W, TAYLOR, Angela E, WINGATE, Anna, NOWAKOWSKA, Karolina, PEZARO, Carmel, CARREIRA, Suzanne, GOODALL, Jane, ARLT, Wiebke

“…Prostate cancer progression can be associated with androgen receptor (AR) mutations acquired following treatment with castration and/or an antiandrogen…”
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Identification of androgen receptor phosphorylation in the primate ovary in vivo by McEwan, Iain J, McGuinness, Dagmara, Hay, Colin W, Millar, Robert P, Saunders, Philippa T K, Fraser, Hamish M

“…The androgen receptor (AR) is a member of the nuclear receptor superfamily, and is important for both male and female reproductive health. The receptor is a…”
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Transcription factor cycling on the insulin promoter by Barrow, John, Hay, Colin W., Ferguson, Laura A., Docherty, Hilary M., Docherty, Kevin

“…Using MIN6 β-cells and chromatin immunoprecipitation (ChIP) assays, the chronological sequence of binding of MafA, E47/β2 and PDX-1 to the insulin promoter in…”
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Glucagon-like peptide-1 stimulates human insulin promoter activity in part through cAMP-responsive elements that lie upstream and downstream of the transcription start site by Hay, Colin W, Sinclair, Elaine M, Bermano, Giovanna, Durward, Elaine, Tadayyon, Mohammad, Docherty, Kevin

“…Glucagon-like peptide-1 (GLP-1) is a peptide hormone secreted from the enteroendocrine L-cells of the gut and which acts primarily to potentiate the effects of…”
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Functional effects of polymorphisms on glucocorticoid receptor modulation of human anxiogenic substance-P gene promoter activity in primary amygdala neurones by Hay, Colin W, Shanley, Lynne, Davidson, Scott, Cowie, Philip, Lear, Marissa, McGuffin, Peter, Riedel, Gernot, McEwan, Iain J, MacKenzie, Alasdair

“…Summary Expression or introduction of the neuropeptide substance-P (SP; encoded by the TAC1 gene in humans and Tac1 in rodents) in the amygdala induces anxiety…”
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ATF-2 stimulates the human insulin promoter through the conserved CRE2 sequence by Hay, Colin W., Ferguson, Laura A., Docherty, Kevin

“…The insulin promoter contains a number of dissimilar cis-acting regulatory elements that bind a range of tissue specific and ubiquitous transcription factors…”
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Comparative Analysis of Insulin Gene Promoters by Hay, Colin W., Docherty, Kevin

“…Comparative Analysis of Insulin Gene Promoters Implications for Diabetes Research Colin W. Hay and Kevin Docherty From the School of Medical Sciences,…”
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Presence of endocrine and exocrine markers in EGFP-positive cells from the developing pancreas of a nestin/EGFP mouse by Bernardo, Andreia S., Barrow, John, Hay, Colin W., McCreath, Kenneth, Kind, Alexander J., Schnieke, Angelika E., Colman, Alan, Hart, Alan W., Docherty, Kevin

“…In order to purify and characterize nestin-positive cells in the developing pancreas a transgenic mouse was generated, in which the enhanced green fluorescent…”
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Negative Regulation of the Androgen Receptor Gene Through a Primate-Specific Androgen Response Element Present in the 5′ UTR by Hay, Colin W., Watt, Kate, Hunter, Irene, Lavery, Derek N., MacKenzie, Alasdair, McEwan, Iain J.

“…The androgen receptor (AR) is a widely expressed ligand-activated transcription factor which mediates androgen signalling by binding to androgen response…”
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Isolation of a human von Willebrand factor cDNA from the hybrid endothelial cell line EA.hy926 by van Oost, B A, Edgell, C J, Hay, C W, MacGillivray, R T

“…A permanent human hybrid endothelial cell line (EA.hy926) was shown to produce the von Willebrand factor, a protein of 250,000 relative mass (Mr) which was…”
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Relative contribution of PDX-1, MafA and E47/ beta 2 to the regulation of the human insulin promoter by Docherty, H M, Hay, C W, Ferguson, LA, Barrow, J, Durward, E, Docherty, K

“…The insulin promoter binds a number of tissue-specific and ubiquitous transcription factors. Of these, the homoeodomain protein PDX-1 (pancreatic duodenal…”
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Histone deacetylase from HeLa cells: properties of the high molecular weight complex by Hay, Colin W, Candido, E. Peter M

“…In previous work [Hay, C. W., & Candido, E. P. M. (1983) J. Biol. Chem. 258, 3726-3734], we have shown that the histone deacetylase from HeLa cell nuclei is…”
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Relative contribution of PDX-1, MafA and E47/beta2 to the regulation of the human insulin promoter by Docherty, Hilary M, Hay, Colin W, Ferguson, Laura A, Barrow, John, Durward, Elaine, Docherty, Kevin

“…The insulin promoter binds a number of tissue-specific and ubiquitous transcription factors. Of these, the homoeodomain protein PDX-1 (pancreatic duodenal…”
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Characterization of an Almost Full-Length cDNA Coding for Human Blood Coagulation Factor X by Fung, Marion R., Hay, Colin W., Ross T. A. Mac Gillivray

“…A human liver cDNA library was screened by colony hybridization with a bovine factor X cDNA probe. Three of the positive plasmids contained overlapping DNA…”
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